FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971290544> ?p ?o ?g. }

• W1971290544 endingPage "408" @default.
• W1971290544 startingPage "400" @default.
• W1971290544 abstract "Deep trophoblast invasion is usually considered to be a unique feature of human placentation as compared to other primates. Because of the occasional occurrence of preeclampsia in great apes, which in the human is associated with impaired deep invasion, this uniqueness may be questioned. The availability of two well-documented pregnant chimpanzee uteri in the Hubrecht Collection (Museum für Naturkunde, Berlin) allowed us to evaluate the extent of trophoblast invasion in this species. By adjusting currently used protocols, we obtained successful immunohistochemical staining for cytokeratin and α-actin, as well as Ulex europaeus agglutinin 1 (UEA1) lectin staining, in this archival material. In both specimens interstitial trophoblast invasion had occurred in both decidua and myometrium. Because of a lack of published data on fetal growth for this species, fetal sizes (7cm and 13cm) could not be strictly related to gestational ages and thus be compared with the time-course of human trophoblast invasion. However, since the earlier specimen did not show any endovascular trophoblast invasion in spiral arteries - in contrast to pregnant human uteri with equivalent fetal sizes - endovascular migration seems to begin at a different gestational age in the chimpanzee. In the later specimen endovascular trophoblast was associated with spiral artery remodelling in the inner myometrium, and this invasion was extended to include a radial artery, which at that stage still showed relatively intact vascular smooth muscle and elastic lamina. We conclude that invasion depth and spiral artery remodelling are basically similar in chimpanzees and humans, although the seemingly different time of onset may have implications for uteroplacental oxygen supply and fetal development." @default.
• W1971290544 created "2016-06-24" @default.
• W1971290544 creator A5044419724 @default.
• W1971290544 creator A5069563115 @default.
• W1971290544 creator A5074180386 @default.
• W1971290544 date "2011-05-01" @default.
• W1971290544 modified "2023-10-02" @default.
• W1971290544 title "Deep trophoblast invasion and spiral artery remodelling in the placental bed of the chimpanzee" @default.
• W1971290544 cites W1515904276 @default.
• W1971290544 cites W1520455808 @default.
• W1971290544 cites W1525674774 @default.
• W1971290544 cites W1585244363 @default.
• W1971290544 cites W171819190 @default.
• W1971290544 cites W1975195151 @default.
• W1971290544 cites W1980328490 @default.
• W1971290544 cites W1981433264 @default.
• W1971290544 cites W1987717520 @default.
• W1971290544 cites W1991430317 @default.
• W1971290544 cites W1993567277 @default.
• W1971290544 cites W1994759365 @default.
• W1971290544 cites W2003493237 @default.
• W1971290544 cites W2018308932 @default.
• W1971290544 cites W2020697426 @default.
• W1971290544 cites W2020837045 @default.
• W1971290544 cites W2030646353 @default.
• W1971290544 cites W2034492080 @default.
• W1971290544 cites W2037446005 @default.
• W1971290544 cites W2040613067 @default.
• W1971290544 cites W2071338376 @default.
• W1971290544 cites W2083935251 @default.
• W1971290544 cites W2091767020 @default.
• W1971290544 cites W2110789099 @default.
• W1971290544 cites W2111984223 @default.
• W1971290544 cites W2115081018 @default.
• W1971290544 cites W2125548284 @default.
• W1971290544 cites W2130766642 @default.
• W1971290544 cites W2153205829 @default.
• W1971290544 cites W2166223726 @default.
• W1971290544 cites W2167950650 @default.
• W1971290544 cites W2291710071 @default.
• W1971290544 cites W2414151249 @default.
• W1971290544 doi "https://doi.org/10.1016/j.placenta.2011.02.009" @default.
• W1971290544 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21459441" @default.
• W1971290544 hasPublicationYear "2011" @default.
• W1971290544 type Work @default.
• W1971290544 sameAs 1971290544 @default.
• W1971290544 citedByCount "48" @default.
• W1971290544 countsByYear W19712905442012 @default.
• W1971290544 countsByYear W19712905442013 @default.
• W1971290544 countsByYear W19712905442014 @default.
• W1971290544 countsByYear W19712905442015 @default.
• W1971290544 countsByYear W19712905442016 @default.
• W1971290544 countsByYear W19712905442017 @default.
• W1971290544 countsByYear W19712905442018 @default.
• W1971290544 countsByYear W19712905442019 @default.
• W1971290544 countsByYear W19712905442020 @default.
• W1971290544 countsByYear W19712905442021 @default.
• W1971290544 countsByYear W19712905442022 @default.
• W1971290544 crossrefType "journal-article" @default.
• W1971290544 hasAuthorship W1971290544A5044419724 @default.
• W1971290544 hasAuthorship W1971290544A5069563115 @default.
• W1971290544 hasAuthorship W1971290544A5074180386 @default.
• W1971290544 hasConcept C105702510 @default.
• W1971290544 hasConcept C134018914 @default.
• W1971290544 hasConcept C142724271 @default.
• W1971290544 hasConcept C16685009 @default.
• W1971290544 hasConcept C172680121 @default.
• W1971290544 hasConcept C2776953305 @default.
• W1971290544 hasConcept C2777495146 @default.
• W1971290544 hasConcept C2778164554 @default.
• W1971290544 hasConcept C2779066055 @default.
• W1971290544 hasConcept C2779234561 @default.
• W1971290544 hasConcept C2780197806 @default.
• W1971290544 hasConcept C2780771523 @default.
• W1971290544 hasConcept C45167389 @default.
• W1971290544 hasConcept C54355233 @default.
• W1971290544 hasConcept C71924100 @default.
• W1971290544 hasConcept C86803240 @default.
• W1971290544 hasConceptScore W1971290544C105702510 @default.
• W1971290544 hasConceptScore W1971290544C134018914 @default.
• W1971290544 hasConceptScore W1971290544C142724271 @default.
• W1971290544 hasConceptScore W1971290544C16685009 @default.
• W1971290544 hasConceptScore W1971290544C172680121 @default.
• W1971290544 hasConceptScore W1971290544C2776953305 @default.
• W1971290544 hasConceptScore W1971290544C2777495146 @default.
• W1971290544 hasConceptScore W1971290544C2778164554 @default.
• W1971290544 hasConceptScore W1971290544C2779066055 @default.
• W1971290544 hasConceptScore W1971290544C2779234561 @default.
• W1971290544 hasConceptScore W1971290544C2780197806 @default.
• W1971290544 hasConceptScore W1971290544C2780771523 @default.
• W1971290544 hasConceptScore W1971290544C45167389 @default.
• W1971290544 hasConceptScore W1971290544C54355233 @default.
• W1971290544 hasConceptScore W1971290544C71924100 @default.
• W1971290544 hasConceptScore W1971290544C86803240 @default.
• W1971290544 hasIssue "5" @default.
• W1971290544 hasLocation W19712905441 @default.
• W1971290544 hasLocation W19712905442 @default.
• W1971290544 hasOpenAccess W1971290544 @default.

• next