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- W1971291262 abstract "1 A gas-liquid chromatography (g.l.c.) method for measurement of the antidepressant nomifensine was developed and compared for precision, accuracy, sensitivity and convenience with radioimmunoassay (RIA). 2 No significant difference was found between the two techniques for unconjugated nomifensine (y = 1.07x = 2.7; r = 0.996) or total nomifensine (y = 1.;02x + 0.02; r = 0.999). 3 RIA proved more sensitive than g.l.c. (detection limit of RIA being 1 microgram/l and g.l.c. 5 micrograms/l). 4 RIA was found to be a more convenient technique (up to 50 samples per day with RIA, and 16 samples with g.l.c.)." @default.
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- W1971291262 date "1981-11-01" @default.
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- W1971291262 title "Determination of nomifensine plasma concentrations: a comparison of radioimmunoassay and gas chromatography." @default.
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- W1971291262 doi "https://doi.org/10.1111/j.1365-2125.1981.tb01291.x" @default.
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