FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971294588> ?p ?o ?g. }

• W1971294588 endingPage "147" @default.
• W1971294588 startingPage "137" @default.
• W1971294588 abstract "The publication of the National Institute of Neurological Disorders and Stroke (NINDS) rt-PA Stroke Trial in 1995 generated considerable hope, but also concerns as to whether the results of this carefully conducted randomized clinical trial can be replicated in routine clinical practice. Steadily accumulating data on use of intravenous t-PA for acute ischemic stroke from multiple postmarketing studies encouragingly show that low complication rates and high rates of favorable outcome can be achieved with proper use of this therapy; however, preliminary data also show that the general applicability of t-PA is uncertain, and the risk of t-PA might potentially outweigh the benefits in some circumstances. Ongoing systemic audits of t-PA use in routine clinical practice have proved useful and provide insight regarding the effect of thrombolysis in different clinical settings. Treatment with t-PA should be used by physicians who are well educated and experienced with its use, patients should be carefully selected, and treatment guidelines must be strictly adhered to. The option of treatment with t-PA is available to a small fraction of patients afflicted with acute stroke, but the proportion of patients who can be treated effectively with thrombolysis has been shown to grow with experience and better organization. Door-to-needle time in most series exceeds the recommended 60-minute goal. Over the last 5 years, large strides were made toward effective urgent therapy with t-PA, but much further work is still required to maximize the benefit for stroke victims. Modern neurovascular imaging techniques might allow for treatment to be appropriately tailored to the individual patient. For now, the original NINDS protocol for patient selection and treatment has borne itself out and remains the standard of care for acute ischemic stroke." @default.
• W1971294588 created "2016-06-24" @default.
• W1971294588 creator A5009170752 @default.
• W1971294588 creator A5020373936 @default.
• W1971294588 creator A5024658913 @default.
• W1971294588 date "2002-05-01" @default.
• W1971294588 modified "2023-09-27" @default.
• W1971294588 title "Intravenous thrombolysis for acute ischemic stroke: The phase IV data" @default.
• W1971294588 cites W1964624569 @default.
• W1971294588 cites W1974638135 @default.
• W1971294588 cites W1979026317 @default.
• W1971294588 cites W1983567452 @default.
• W1971294588 cites W1984969350 @default.
• W1971294588 cites W1998257407 @default.
• W1971294588 cites W2016010242 @default.
• W1971294588 cites W2020303089 @default.
• W1971294588 cites W2023766166 @default.
• W1971294588 cites W2045893060 @default.
• W1971294588 cites W2048614158 @default.
• W1971294588 cites W2056575590 @default.
• W1971294588 cites W2061599477 @default.
• W1971294588 cites W2061751634 @default.
• W1971294588 cites W2065063783 @default.
• W1971294588 cites W2072037976 @default.
• W1971294588 cites W2094643380 @default.
• W1971294588 cites W2095603614 @default.
• W1971294588 cites W2096789042 @default.
• W1971294588 cites W2106156519 @default.
• W1971294588 cites W2107887981 @default.
• W1971294588 cites W2108506714 @default.
• W1971294588 cites W2112053016 @default.
• W1971294588 cites W2112077039 @default.
• W1971294588 cites W2112573578 @default.
• W1971294588 cites W2113483365 @default.
• W1971294588 cites W2115227644 @default.
• W1971294588 cites W2118738743 @default.
• W1971294588 cites W2122794709 @default.
• W1971294588 cites W2126500137 @default.
• W1971294588 cites W2127554663 @default.
• W1971294588 cites W2129036957 @default.
• W1971294588 cites W2131182553 @default.
• W1971294588 cites W2137562410 @default.
• W1971294588 cites W2143000724 @default.
• W1971294588 cites W2146048043 @default.
• W1971294588 cites W2147358850 @default.
• W1971294588 cites W2148656951 @default.
• W1971294588 cites W2148750186 @default.
• W1971294588 cites W2150361369 @default.
• W1971294588 cites W2155390662 @default.
• W1971294588 cites W2155758555 @default.
• W1971294588 cites W2157862517 @default.
• W1971294588 cites W2164374762 @default.
• W1971294588 cites W2167970222 @default.
• W1971294588 cites W2171764120 @default.
• W1971294588 cites W2292308933 @default.
• W1971294588 cites W2335000692 @default.
• W1971294588 cites W2337100493 @default.
• W1971294588 cites W2473677233 @default.
• W1971294588 cites W254834723 @default.
• W1971294588 cites W2984210412 @default.
• W1971294588 cites W3205926832 @default.
• W1971294588 cites W3208775091 @default.
• W1971294588 cites W3105389802 @default.
• W1971294588 doi "https://doi.org/10.1053/jscd.2002.129959" @default.
• W1971294588 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17903870" @default.
• W1971294588 hasPublicationYear "2002" @default.
• W1971294588 type Work @default.
• W1971294588 sameAs 1971294588 @default.
• W1971294588 citedByCount "1" @default.
• W1971294588 crossrefType "journal-article" @default.
• W1971294588 hasAuthorship W1971294588A5009170752 @default.
• W1971294588 hasAuthorship W1971294588A5020373936 @default.
• W1971294588 hasAuthorship W1971294588A5024658913 @default.
• W1971294588 hasConcept C105572291 @default.
• W1971294588 hasConcept C126322002 @default.
• W1971294588 hasConcept C127413603 @default.
• W1971294588 hasConcept C141071460 @default.
• W1971294588 hasConcept C162324750 @default.
• W1971294588 hasConcept C168563851 @default.
• W1971294588 hasConcept C177713679 @default.
• W1971294588 hasConcept C1862650 @default.
• W1971294588 hasConcept C187736073 @default.
• W1971294588 hasConcept C194828623 @default.
• W1971294588 hasConcept C199521495 @default.
• W1971294588 hasConcept C2779581417 @default.
• W1971294588 hasConcept C2779974597 @default.
• W1971294588 hasConcept C2780645631 @default.
• W1971294588 hasConcept C3020199598 @default.
• W1971294588 hasConcept C500558357 @default.
• W1971294588 hasConcept C535046627 @default.
• W1971294588 hasConcept C541997718 @default.
• W1971294588 hasConcept C71924100 @default.
• W1971294588 hasConcept C78519656 @default.
• W1971294588 hasConceptScore W1971294588C105572291 @default.
• W1971294588 hasConceptScore W1971294588C126322002 @default.
• W1971294588 hasConceptScore W1971294588C127413603 @default.
• W1971294588 hasConceptScore W1971294588C141071460 @default.
• W1971294588 hasConceptScore W1971294588C162324750 @default.

• next