FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971294710> ?p ?o ?g. }

• W1971294710 endingPage "325" @default.
• W1971294710 startingPage "323" @default.
• W1971294710 abstract "The thermal stability of two single (K3R, K67R) and one double (K3R-K67R) mutants of Xenopus laevis B Cu, Zn superoxide dismutase has been studied to test Lys --> Arg substitution as an 'electrostatically conservative' strategy to increase protein stability. The K3R mutant displays an increased thermostability with respect to the wild-type enzyme, whilst a decreased stability was observed in the case of the K67R and K3R-K67R mutants. Concentration dependence of the apparent inactivation constant (kapp) of the latter mutants, as compared to that of the wild type enzyme and K3R mutant, indicates that their higher sensitivity to heat inactivation is due to a perturbation of the dimer association. These results are confirmed also by fluorescence anisotropy measurements of the internal probe Tyr149. The possible role of Arg67 in perturbing the dimer dissociation equilibrium toward the monomeric form is discussed." @default.
• W1971294710 created "2016-06-24" @default.
• W1971294710 creator A5002520527 @default.
• W1971294710 creator A5018585630 @default.
• W1971294710 creator A5019534523 @default.
• W1971294710 creator A5021690286 @default.
• W1971294710 creator A5022702349 @default.
• W1971294710 creator A5027631201 @default.
• W1971294710 creator A5052993222 @default.
• W1971294710 creator A5060797776 @default.
• W1971294710 creator A5077448942 @default.
• W1971294710 creator A5079354466 @default.
• W1971294710 date "1996-01-01" @default.
• W1971294710 modified "2023-09-23" @default.
• W1971294710 title "Effect of Lys→Arg mutation on the thermal stability of Cu,Zn superoxide dismutase: influence on the monomer–dimer equilibrium" @default.
• W1971294710 cites W2129995310 @default.
• W1971294710 doi "https://doi.org/10.1093/protein/9.4.323" @default.
• W1971294710 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8738207" @default.
• W1971294710 hasPublicationYear "1996" @default.
• W1971294710 type Work @default.
• W1971294710 sameAs 1971294710 @default.
• W1971294710 citedByCount "20" @default.
• W1971294710 countsByYear W19712947102012 @default.
• W1971294710 countsByYear W19712947102013 @default.
• W1971294710 countsByYear W19712947102014 @default.
• W1971294710 countsByYear W19712947102016 @default.
• W1971294710 countsByYear W19712947102017 @default.
• W1971294710 countsByYear W19712947102020 @default.
• W1971294710 crossrefType "journal-article" @default.
• W1971294710 hasAuthorship W1971294710A5002520527 @default.
• W1971294710 hasAuthorship W1971294710A5018585630 @default.
• W1971294710 hasAuthorship W1971294710A5019534523 @default.
• W1971294710 hasAuthorship W1971294710A5021690286 @default.
• W1971294710 hasAuthorship W1971294710A5022702349 @default.
• W1971294710 hasAuthorship W1971294710A5027631201 @default.
• W1971294710 hasAuthorship W1971294710A5052993222 @default.
• W1971294710 hasAuthorship W1971294710A5060797776 @default.
• W1971294710 hasAuthorship W1971294710A5077448942 @default.
• W1971294710 hasAuthorship W1971294710A5079354466 @default.
• W1971294710 hasBestOaLocation W19712947101 @default.
• W1971294710 hasConcept C102931765 @default.
• W1971294710 hasConcept C104317684 @default.
• W1971294710 hasConcept C12554922 @default.
• W1971294710 hasConcept C143065580 @default.
• W1971294710 hasConcept C147789679 @default.
• W1971294710 hasConcept C166940927 @default.
• W1971294710 hasConcept C170493617 @default.
• W1971294710 hasConcept C178790620 @default.
• W1971294710 hasConcept C181199279 @default.
• W1971294710 hasConcept C185592680 @default.
• W1971294710 hasConcept C2775838275 @default.
• W1971294710 hasConcept C2779535977 @default.
• W1971294710 hasConcept C2779546866 @default.
• W1971294710 hasConcept C2781216036 @default.
• W1971294710 hasConcept C521977710 @default.
• W1971294710 hasConcept C55493867 @default.
• W1971294710 hasConcept C59061564 @default.
• W1971294710 hasConcept C74998103 @default.
• W1971294710 hasConcept C8010536 @default.
• W1971294710 hasConcept C86803240 @default.
• W1971294710 hasConceptScore W1971294710C102931765 @default.
• W1971294710 hasConceptScore W1971294710C104317684 @default.
• W1971294710 hasConceptScore W1971294710C12554922 @default.
• W1971294710 hasConceptScore W1971294710C143065580 @default.
• W1971294710 hasConceptScore W1971294710C147789679 @default.
• W1971294710 hasConceptScore W1971294710C166940927 @default.
• W1971294710 hasConceptScore W1971294710C170493617 @default.
• W1971294710 hasConceptScore W1971294710C178790620 @default.
• W1971294710 hasConceptScore W1971294710C181199279 @default.
• W1971294710 hasConceptScore W1971294710C185592680 @default.
• W1971294710 hasConceptScore W1971294710C2775838275 @default.
• W1971294710 hasConceptScore W1971294710C2779535977 @default.
• W1971294710 hasConceptScore W1971294710C2779546866 @default.
• W1971294710 hasConceptScore W1971294710C2781216036 @default.
• W1971294710 hasConceptScore W1971294710C521977710 @default.
• W1971294710 hasConceptScore W1971294710C55493867 @default.
• W1971294710 hasConceptScore W1971294710C59061564 @default.
• W1971294710 hasConceptScore W1971294710C74998103 @default.
• W1971294710 hasConceptScore W1971294710C8010536 @default.
• W1971294710 hasConceptScore W1971294710C86803240 @default.
• W1971294710 hasIssue "4" @default.
• W1971294710 hasLocation W19712947101 @default.
• W1971294710 hasLocation W19712947102 @default.
• W1971294710 hasOpenAccess W1971294710 @default.
• W1971294710 hasPrimaryLocation W19712947101 @default.
• W1971294710 hasRelatedWork W1965051780 @default.
• W1971294710 hasRelatedWork W2009588634 @default.
• W1971294710 hasRelatedWork W2009679945 @default.
• W1971294710 hasRelatedWork W2009835496 @default.
• W1971294710 hasRelatedWork W2038502229 @default.
• W1971294710 hasRelatedWork W2058412448 @default.
• W1971294710 hasRelatedWork W2064045307 @default.
• W1971294710 hasRelatedWork W2492453379 @default.
• W1971294710 hasRelatedWork W894828802 @default.
• W1971294710 hasRelatedWork W2507893968 @default.
• W1971294710 hasVolume "9" @default.
• W1971294710 isParatext "false" @default.
• W1971294710 isRetracted "false" @default.

• next