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- W1971295944 abstract "This study was carried out to investigate the possible role of adhesion molecules in the histamine release from human basophils primed with recombinant IL-3 (rIL-3). Anti-IgE monoclonal antibody (0.1 microgram/ml) did not induce apparent histamine release by itself, however, remarkable histamine release was induced from rIL-3-primed human basophils triggered by anti-IgE. Bear-1 (anti-CD11b monoclonal antibody) inhibited the histamine release enhanced by rIL-3, however SPV-L7 (anti-CD11a monoclonal antibody) or CLB-LFA1/1 (anti-CD18 monoclonal antibody) did not inhibit the histamine release enhanced by rIL-3 at all. The present study suggests that alpha-chain of Mac-1 is involved in the priming effect of IL-3 to increase histamine release from human basophils." @default.
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- W1971295944 date "1992-01-01" @default.
- W1971295944 modified "2023-09-25" @default.
- W1971295944 title "Effects of Anti-CD11a, Anti-CD11b and Anti-CD 18 on Histamine Release from Human Basophils Primed with IL-3" @default.
- W1971295944 doi "https://doi.org/10.1159/000236203" @default.
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