Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971297568> ?p ?o ?g. }
- W1971297568 endingPage "114" @default.
- W1971297568 startingPage "105" @default.
- W1971297568 abstract "Normal human diploid cells have a limited proliferative lifespan in in vitro cultures. Changes in gene expression have been examined for understanding control mechanisms of limited proliferative lifespan. and enhanced expression of growth suppressing genes such as p21 was reported in late-passaged cells. We screened genes which were expressed preferentially in mid-passaged cells by the differential plaque screening of the subtracted cDNA libraries prepared from young, life-extended, and immortalized SV40-transformed human fibroblasts. Among isolated clones, ASF/SF2, which was known to affect alternative splicing, was expressed in normal fibroblasts with a peak at mid-passage. Relative expression levels of SC35 and hnRNPA1, which are also known to affect alternative splicing, was also highest at mid-passage. Changes in alternative splicing at mid-passage, if it occurred, may play a crucial role in the process of cellular senescence." @default.
- W1971297568 created "2016-06-24" @default.
- W1971297568 creator A5012102867 @default.
- W1971297568 creator A5013776416 @default.
- W1971297568 creator A5023488159 @default.
- W1971297568 date "1998-09-01" @default.
- W1971297568 modified "2023-09-26" @default.
- W1971297568 title "Expressional changes in alternative splicing affecting genes during cell passage of human diploid fibroblasts" @default.
- W1971297568 cites W1486929331 @default.
- W1971297568 cites W1604903306 @default.
- W1971297568 cites W1604926853 @default.
- W1971297568 cites W1625736061 @default.
- W1971297568 cites W1966797025 @default.
- W1971297568 cites W1967932820 @default.
- W1971297568 cites W1969019995 @default.
- W1971297568 cites W1971956957 @default.
- W1971297568 cites W1974331672 @default.
- W1971297568 cites W1979669293 @default.
- W1971297568 cites W1982151076 @default.
- W1971297568 cites W1985112767 @default.
- W1971297568 cites W1987459898 @default.
- W1971297568 cites W1991477412 @default.
- W1971297568 cites W1992829869 @default.
- W1971297568 cites W1994082723 @default.
- W1971297568 cites W1998251495 @default.
- W1971297568 cites W2002385126 @default.
- W1971297568 cites W2004314923 @default.
- W1971297568 cites W2004497068 @default.
- W1971297568 cites W2007772649 @default.
- W1971297568 cites W2022225463 @default.
- W1971297568 cites W2024849327 @default.
- W1971297568 cites W2025047823 @default.
- W1971297568 cites W2027183714 @default.
- W1971297568 cites W2027782700 @default.
- W1971297568 cites W2032428064 @default.
- W1971297568 cites W2035856374 @default.
- W1971297568 cites W2039263836 @default.
- W1971297568 cites W2043449536 @default.
- W1971297568 cites W2045941914 @default.
- W1971297568 cites W2047330128 @default.
- W1971297568 cites W2051146905 @default.
- W1971297568 cites W2057628471 @default.
- W1971297568 cites W2060298337 @default.
- W1971297568 cites W2066394091 @default.
- W1971297568 cites W2066514458 @default.
- W1971297568 cites W2066552951 @default.
- W1971297568 cites W2068354335 @default.
- W1971297568 cites W2070808519 @default.
- W1971297568 cites W2071336621 @default.
- W1971297568 cites W2073112405 @default.
- W1971297568 cites W2078596153 @default.
- W1971297568 cites W2082127202 @default.
- W1971297568 cites W2085797277 @default.
- W1971297568 cites W2086930994 @default.
- W1971297568 cites W2090303261 @default.
- W1971297568 cites W2091797313 @default.
- W1971297568 cites W2104525623 @default.
- W1971297568 cites W2106767328 @default.
- W1971297568 cites W2109291482 @default.
- W1971297568 cites W2117976997 @default.
- W1971297568 cites W2150487020 @default.
- W1971297568 cites W2151078655 @default.
- W1971297568 cites W2156650182 @default.
- W1971297568 cites W2186089638 @default.
- W1971297568 cites W2326889200 @default.
- W1971297568 doi "https://doi.org/10.1016/s0047-6374(98)00082-7" @default.
- W1971297568 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9922122" @default.
- W1971297568 hasPublicationYear "1998" @default.
- W1971297568 type Work @default.
- W1971297568 sameAs 1971297568 @default.
- W1971297568 citedByCount "6" @default.
- W1971297568 countsByYear W19712975682022 @default.
- W1971297568 crossrefType "journal-article" @default.
- W1971297568 hasAuthorship W1971297568A5012102867 @default.
- W1971297568 hasAuthorship W1971297568A5013776416 @default.
- W1971297568 hasAuthorship W1971297568A5023488159 @default.
- W1971297568 hasConcept C104317684 @default.
- W1971297568 hasConcept C127716648 @default.
- W1971297568 hasConcept C143191323 @default.
- W1971297568 hasConcept C150194340 @default.
- W1971297568 hasConcept C153911025 @default.
- W1971297568 hasConcept C187882448 @default.
- W1971297568 hasConcept C190474072 @default.
- W1971297568 hasConcept C194583182 @default.
- W1971297568 hasConcept C2780381497 @default.
- W1971297568 hasConcept C36823959 @default.
- W1971297568 hasConcept C522857546 @default.
- W1971297568 hasConcept C54355233 @default.
- W1971297568 hasConcept C54458228 @default.
- W1971297568 hasConcept C67705224 @default.
- W1971297568 hasConcept C81885089 @default.
- W1971297568 hasConcept C86803240 @default.
- W1971297568 hasConcept C95444343 @default.
- W1971297568 hasConceptScore W1971297568C104317684 @default.
- W1971297568 hasConceptScore W1971297568C127716648 @default.
- W1971297568 hasConceptScore W1971297568C143191323 @default.
- W1971297568 hasConceptScore W1971297568C150194340 @default.
- W1971297568 hasConceptScore W1971297568C153911025 @default.