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- W1971377175 abstract "Nitric oxide (NO) mediates multiple physiological and pathophysiological processes in the cardiovascular system. Pharmacological compounds that release NO have been useful tools for evaluating the pivotal role of NO in cardiovascular physiology and therapeutics. These agents constitute two broad classes of compounds, those that release NO or one of its redox congeners spontaneously and those that require enzymatic metabolism to generate NO. In addition, several commonly used cardiovascular drugs exert their beneficial action, in part, by modulating the NO pathway. Here, we review these classes of agents, summarizing their fundamental chemistry and pharmacology, and provide an overview of their cardiovascular mechanisms of action." @default.
- W1971377175 created "2016-06-24" @default.
- W1971377175 creator A5028396638 @default.
- W1971377175 creator A5061269136 @default.
- W1971377175 creator A5073202155 @default.
- W1971377175 date "2002-01-11" @default.
- W1971377175 modified "2023-10-03" @default.
- W1971377175 title "Nitric Oxide Donors and Cardiovascular Agents Modulating the Bioactivity of Nitric Oxide" @default.
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- W1971377175 doi "https://doi.org/10.1161/hh0102.102330" @default.
- W1971377175 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11786514" @default.
- W1971377175 hasPublicationYear "2002" @default.
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