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- W1971452585 abstract "Clinical and haematological features of 13 patients with secondary myelodysplastic syndromes (MDS) were studied, MDS developed subsequent to chemotherapy and/or radiotherapy for various haematological or non-haematological diseases. In six cases, the first sign was a persistently increased mean cell volume (MCV) and a macrocytosis preceding from 6 to 18 months the appearance of severe anaemia or acute leukaemia. In five cases, the initial finding was a macrocytic anaemia. Dysmyelopoiesis was a constant and prominent feature of the bone marrow smears at some time during the course of the disease. Two cases without macrocytosis at any time directly developed overt acute leukaemia." @default.
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- W1971452585 date "1980-06-01" @default.
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- W1971452585 title "Myelodysplasia and leukaemia related to chemotherapy and/or radiotherapy-a haematological study of 13 cases. Value of macrocytosis as an early sign of bone marrow injury" @default.
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- W1971452585 doi "https://doi.org/10.1111/j.1365-2257.1980.tb00814.x" @default.
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