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• W1971473876 abstract "Biopsies of lesions from molluscum contagiosum from 3 children were studied by light and electron microscopy. The lesion appears to be a mass of proliferating epidermal cells extending in grapelike clusters into the dermis. These epidermal cells undergo various stages of differentiation culminating in the formation of cytoplasmic inclusions. The cytoplasmic inclusions contain virus particles in different stages of maturation. “Uninfected” epidermal cells, in stages of normal maturation, are interspersed among “infected” cells containing virus particles. A maturational sequence of virus particle development is suggested on the basis of the electron microscopic observations. Biopsies of lesions from molluscum contagiosum from 3 children were studied by light and electron microscopy. The lesion appears to be a mass of proliferating epidermal cells extending in grapelike clusters into the dermis. These epidermal cells undergo various stages of differentiation culminating in the formation of cytoplasmic inclusions. The cytoplasmic inclusions contain virus particles in different stages of maturation. “Uninfected” epidermal cells, in stages of normal maturation, are interspersed among “infected” cells containing virus particles. A maturational sequence of virus particle development is suggested on the basis of the electron microscopic observations." @default.
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• W1971473876 date "1964-06-01" @default.
• W1971473876 modified "2023-10-14" @default.
• W1971473876 title "The ultrastructure and histogenesis of molluscum contagiosum" @default.
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• W1971473876 doi "https://doi.org/10.1016/s0022-3476(64)80646-6" @default.
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