Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971490990> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W1971490990 endingPage "62" @default.
- W1971490990 startingPage "60" @default.
- W1971490990 abstract "New HLA alleles can be identified by unorthodox patterns observed during low-resolution typing performed with sequence specific oligonucleotide probes (SSOP). One of the best examples is locus DRB1, where allelic subtypes are characterized by a combination of a limited number of residues located in three hypervariable regions of exon 2. HLA-DR oligotyping analysis of a female caucasoid bone marrow donor led to the identification of an individual that typed as DRB1∗11, DRB3∗02, DRB4∗01, DQB1∗0301–0302. This donor was, however, typed by serology as DR11 DR4, DR52 DR53, DQ7 DQ8. PCR-SSP typing for DR4 subtype revealed an amplification pattern typical for DRB1∗0404. After sequencing the entire exon 2, a new DRB1 allele was identified: DRBl∗04var that is identical to DRB1∗0404, except for one nucleotide at codon 88 resulting in a Ser → Arg exchange. This mutation had prevented amplification with the DR generic primers. Cellular typing by three HTCs—DRB1∗0404/DW14 from the 9th Workshop showed that this DRB1∗04var typed exactly like a DW14 cell. This suggests that residue 88 does not affect T cell recognition." @default.
- W1971490990 created "2016-06-24" @default.
- W1971490990 creator A5004294980 @default.
- W1971490990 creator A5012220567 @default.
- W1971490990 creator A5027084876 @default.
- W1971490990 creator A5033405500 @default.
- W1971490990 creator A5034805452 @default.
- W1971490990 creator A5040986911 @default.
- W1971490990 creator A5081112781 @default.
- W1971490990 date "1996-11-01" @default.
- W1971490990 modified "2023-10-16" @default.
- W1971490990 title "Sequence of a new HLA-DR4 allele with an unusual residue at position 88 that does not seem to affect T-cell allo recognition" @default.
- W1971490990 cites W1995593914 @default.
- W1971490990 cites W2000677694 @default.
- W1971490990 cites W2021163862 @default.
- W1971490990 cites W2045094845 @default.
- W1971490990 cites W2051494619 @default.
- W1971490990 cites W2082568578 @default.
- W1971490990 cites W2163521262 @default.
- W1971490990 cites W2297298993 @default.
- W1971490990 doi "https://doi.org/10.1016/s0198-8859(96)00153-x" @default.
- W1971490990 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8911999" @default.
- W1971490990 hasPublicationYear "1996" @default.
- W1971490990 type Work @default.
- W1971490990 sameAs 1971490990 @default.
- W1971490990 citedByCount "6" @default.
- W1971490990 countsByYear W19714909902021 @default.
- W1971490990 crossrefType "journal-article" @default.
- W1971490990 hasAuthorship W1971490990A5004294980 @default.
- W1971490990 hasAuthorship W1971490990A5012220567 @default.
- W1971490990 hasAuthorship W1971490990A5027084876 @default.
- W1971490990 hasAuthorship W1971490990A5033405500 @default.
- W1971490990 hasAuthorship W1971490990A5034805452 @default.
- W1971490990 hasAuthorship W1971490990A5040986911 @default.
- W1971490990 hasAuthorship W1971490990A5081112781 @default.
- W1971490990 hasConcept C104317684 @default.
- W1971490990 hasConcept C129312508 @default.
- W1971490990 hasConcept C147483822 @default.
- W1971490990 hasConcept C153911025 @default.
- W1971490990 hasConcept C180754005 @default.
- W1971490990 hasConcept C188280979 @default.
- W1971490990 hasConcept C2781209916 @default.
- W1971490990 hasConcept C36823959 @default.
- W1971490990 hasConcept C54355233 @default.
- W1971490990 hasConcept C552990157 @default.
- W1971490990 hasConcept C81566733 @default.
- W1971490990 hasConcept C84148353 @default.
- W1971490990 hasConcept C84597430 @default.
- W1971490990 hasConcept C86803240 @default.
- W1971490990 hasConceptScore W1971490990C104317684 @default.
- W1971490990 hasConceptScore W1971490990C129312508 @default.
- W1971490990 hasConceptScore W1971490990C147483822 @default.
- W1971490990 hasConceptScore W1971490990C153911025 @default.
- W1971490990 hasConceptScore W1971490990C180754005 @default.
- W1971490990 hasConceptScore W1971490990C188280979 @default.
- W1971490990 hasConceptScore W1971490990C2781209916 @default.
- W1971490990 hasConceptScore W1971490990C36823959 @default.
- W1971490990 hasConceptScore W1971490990C54355233 @default.
- W1971490990 hasConceptScore W1971490990C552990157 @default.
- W1971490990 hasConceptScore W1971490990C81566733 @default.
- W1971490990 hasConceptScore W1971490990C84148353 @default.
- W1971490990 hasConceptScore W1971490990C84597430 @default.
- W1971490990 hasConceptScore W1971490990C86803240 @default.
- W1971490990 hasIssue "1" @default.
- W1971490990 hasLocation W19714909901 @default.
- W1971490990 hasLocation W19714909902 @default.
- W1971490990 hasOpenAccess W1971490990 @default.
- W1971490990 hasPrimaryLocation W19714909901 @default.
- W1971490990 hasRelatedWork W1505876351 @default.
- W1971490990 hasRelatedWork W2034268012 @default.
- W1971490990 hasRelatedWork W2042244817 @default.
- W1971490990 hasRelatedWork W2054826199 @default.
- W1971490990 hasRelatedWork W2057739827 @default.
- W1971490990 hasRelatedWork W2105636594 @default.
- W1971490990 hasRelatedWork W2131411894 @default.
- W1971490990 hasRelatedWork W2313558987 @default.
- W1971490990 hasRelatedWork W2411054033 @default.
- W1971490990 hasRelatedWork W3032525565 @default.
- W1971490990 hasVolume "51" @default.
- W1971490990 isParatext "false" @default.
- W1971490990 isRetracted "false" @default.
- W1971490990 magId "1971490990" @default.
- W1971490990 workType "article" @default.