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- W1971494128 abstract "Results The phenotypic analysis showed a significant reduction of CD8+ T naive cells in VI-ART (P = 0.014) and VI-NO ART (P = 0.003) compared to healthy group. The functional analysis revealed that all HIV-infected patients of our study had CD4+ and CD8+ secreting IFN-γ and/or IL-2 in response to our pool of HIV-1 peptides. This recognition involved central memory (TCM, CCR7+CD45RA-), effector memory (TEM, CCR7-CD45RA-), and CD45RA+ effector memory (TEMRA, CCR7-CD45RA+). In the CD4+ compartment the VI-ART group showed the smallest frequency of functional memory in response to our HIV pooled peptides. This observation was more evident in respect to IL-2 producing cells." @default.
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- W1971494128 date "2009-10-01" @default.
- W1971494128 modified "2023-10-16" @default.
- W1971494128 title "P16-53. Distinct subsets of memory T lymphocytes from HIV-1-infected subjects secrete IFN-γ and IL-2 in response to novel CD4+ T-cell HIV-1 epitopes" @default.
- W1971494128 doi "https://doi.org/10.1186/1742-4690-6-s3-p282" @default.
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