Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971503885> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W1971503885 endingPage "926" @default.
- W1971503885 startingPage "921" @default.
- W1971503885 abstract "Hydroxycitronellal, an important ingredient in fragrances, was studied for its sensitizing potential in human skin. Fifteen human maximization tests were conducted with hydroxycitronellal obtained from four different sources at induction concentrations from 5 to 12%. No reactions were induced at 5% in two separate panels while 10% sensitized 2/25 panelists in one test but none in a second. Induction at 12% produced sensitization in 8 of 11 tests. Impurities do not appear to be a sensitizing factor. There is some evidence that the l-stereoisomer is a less potent sensitizer than the d-stereoisomer. In an initial modified human repeat-insult patch-test two positive reactions to challenge were observed among 197 panelists, one at a concentration of 5% and the other at 7.5%. When 100 of the non-reacting panelists were re-exposed in the same way, allergic sensitization reactions appeared during the induction period with concentrations as low as 2.5%. When 28 sensitized panelists were exposed to 1% concentrations in a simulated use test, there were three reactors. A no-effect level for sensitization has not been determined although the lowest concentrations tested were in the product usage range." @default.
- W1971503885 created "2016-06-24" @default.
- W1971503885 creator A5016714593 @default.
- W1971503885 creator A5042448938 @default.
- W1971503885 creator A5087952713 @default.
- W1971503885 date "1988-01-01" @default.
- W1971503885 modified "2023-10-17" @default.
- W1971503885 title "Allergic contact sensitization potential of hydroxycitronellal in humans" @default.
- W1971503885 cites W2001387755 @default.
- W1971503885 cites W2004590673 @default.
- W1971503885 cites W2012814550 @default.
- W1971503885 cites W2037369355 @default.
- W1971503885 cites W2051614718 @default.
- W1971503885 cites W2060309275 @default.
- W1971503885 cites W2060759454 @default.
- W1971503885 cites W2062611028 @default.
- W1971503885 cites W2081971524 @default.
- W1971503885 cites W2106530153 @default.
- W1971503885 cites W2125998531 @default.
- W1971503885 cites W2170836240 @default.
- W1971503885 cites W4205747435 @default.
- W1971503885 doi "https://doi.org/10.1016/0278-6915(88)90090-7" @default.
- W1971503885 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3264801" @default.
- W1971503885 hasPublicationYear "1988" @default.
- W1971503885 type Work @default.
- W1971503885 sameAs 1971503885 @default.
- W1971503885 citedByCount "29" @default.
- W1971503885 countsByYear W19715038852012 @default.
- W1971503885 countsByYear W19715038852014 @default.
- W1971503885 countsByYear W19715038852017 @default.
- W1971503885 countsByYear W19715038852023 @default.
- W1971503885 crossrefType "journal-article" @default.
- W1971503885 hasAuthorship W1971503885A5016714593 @default.
- W1971503885 hasAuthorship W1971503885A5042448938 @default.
- W1971503885 hasAuthorship W1971503885A5087952713 @default.
- W1971503885 hasConcept C140764562 @default.
- W1971503885 hasConcept C178790620 @default.
- W1971503885 hasConcept C185592680 @default.
- W1971503885 hasConcept C203014093 @default.
- W1971503885 hasConcept C207480886 @default.
- W1971503885 hasConcept C2776056826 @default.
- W1971503885 hasConcept C2776217527 @default.
- W1971503885 hasConcept C2780373086 @default.
- W1971503885 hasConcept C29730261 @default.
- W1971503885 hasConcept C3018346242 @default.
- W1971503885 hasConcept C71924100 @default.
- W1971503885 hasConcept C98274493 @default.
- W1971503885 hasConceptScore W1971503885C140764562 @default.
- W1971503885 hasConceptScore W1971503885C178790620 @default.
- W1971503885 hasConceptScore W1971503885C185592680 @default.
- W1971503885 hasConceptScore W1971503885C203014093 @default.
- W1971503885 hasConceptScore W1971503885C207480886 @default.
- W1971503885 hasConceptScore W1971503885C2776056826 @default.
- W1971503885 hasConceptScore W1971503885C2776217527 @default.
- W1971503885 hasConceptScore W1971503885C2780373086 @default.
- W1971503885 hasConceptScore W1971503885C29730261 @default.
- W1971503885 hasConceptScore W1971503885C3018346242 @default.
- W1971503885 hasConceptScore W1971503885C71924100 @default.
- W1971503885 hasConceptScore W1971503885C98274493 @default.
- W1971503885 hasIssue "11-12" @default.
- W1971503885 hasLocation W19715038851 @default.
- W1971503885 hasLocation W19715038852 @default.
- W1971503885 hasOpenAccess W1971503885 @default.
- W1971503885 hasPrimaryLocation W19715038851 @default.
- W1971503885 hasRelatedWork W1966545836 @default.
- W1971503885 hasRelatedWork W1971503885 @default.
- W1971503885 hasRelatedWork W1972305153 @default.
- W1971503885 hasRelatedWork W2054865262 @default.
- W1971503885 hasRelatedWork W2063021494 @default.
- W1971503885 hasRelatedWork W2098476153 @default.
- W1971503885 hasRelatedWork W2105498110 @default.
- W1971503885 hasRelatedWork W2616513076 @default.
- W1971503885 hasRelatedWork W4210850534 @default.
- W1971503885 hasRelatedWork W4224028166 @default.
- W1971503885 hasVolume "26" @default.
- W1971503885 isParatext "false" @default.
- W1971503885 isRetracted "false" @default.
- W1971503885 magId "1971503885" @default.
- W1971503885 workType "article" @default.