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- W1971562139 abstract "The number of cardiac beta-adrenergic receptors identified by [3H]dihydroalprenolol binding decreases in a concentration-dependent manner during prolonged administration of isoproterenol. Loss of membrane beta-receptors is paralleled by the appearance of [3H]dihydroalprenolol binding activity in the cytosol. This redistribution of receptors is prevented by colchicine and vinblastine but not lumicolchicine. Cardiac receptor desensitization is, therefore, dependent on microtubules and may be influenced by agents interfering with tubulin polymerization." @default.
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- W1971562139 title "Involvement of microtubules in the isoproterenol-induced ‘down’-regulation of myocardial β-adrenergic receptors" @default.
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- W1971562139 doi "https://doi.org/10.1016/0005-2736(83)90273-0" @default.
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