FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971562495> ?p ?o ?g. }

• W1971562495 endingPage "258" @default.
• W1971562495 startingPage "253" @default.
• W1971562495 abstract "Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that is known to be chemosensitive. In patients with TNBC, we sought to compare survival outcomes between patients receiving neoadjuvant chemotherapy, with and without complete pathologic response (pCR), and those receiving adjuvant chemotherapy.We performed a retrospective chart review and identified 385 patients with stage I-III TNBC who were treated with neoadjuvant or adjuvant chemotherapy between 2000 and 2008. Patients were divided according to receipt of neoadjuvant chemotherapy with pCR, neoadjuvant chemotherapy without pCR, and adjuvant chemotherapy. Data were compared using Fisher's exact test and analysis of variance (ANOVA). Kaplan-Meier curves were generated.Of 385 patients, 151 (39%) received neoadjuvant chemotherapy and 234 (61%) received adjuvant chemotherapy. Twenty-six (17%) of those patients receiving neoadjuvant chemotherapy had pCR. After controlling for covariates associated with survival in unadjusted tests, patients undergoing neoadjuvant chemotherapy with residual tumor had significantly worse survival compared with patients receiving adjuvant therapy [hazard ratio (HR) = 0.51, P = 0.007] and a trend towards worse survival compared with patients receiving neoadjuvant therapy with pCR (HR = 0.19, P = 0.10).Although previous clinical trials have not demonstrated a survival difference between patients receiving neoadjuvant versus adjuvant chemotherapy for breast cancer, our study suggests an overall survival benefit in patients with pCR following neoadjuvant chemotherapy compared with patients receiving adjuvant therapy. It is clear that a prospective study needs to be carried out to better elucidate the timing of chemotherapy in patients with TNBC." @default.
• W1971562495 created "2016-06-24" @default.
• W1971562495 creator A5008654358 @default.
• W1971562495 creator A5009199118 @default.
• W1971562495 creator A5032371242 @default.
• W1971562495 creator A5050528770 @default.
• W1971562495 creator A5054757298 @default.
• W1971562495 creator A5061892063 @default.
• W1971562495 creator A5082828758 @default.
• W1971562495 date "2011-07-02" @default.
• W1971562495 modified "2023-10-03" @default.
• W1971562495 title "Neoadjuvant Chemotherapy Is Associated with Improved Survival Compared with Adjuvant Chemotherapy in Patients with Triple-Negative Breast Cancer Only after Complete Pathologic Response" @default.
• W1971562495 cites W1861588860 @default.
• W1971562495 cites W1989663680 @default.
• W1971562495 cites W2057084727 @default.
• W1971562495 cites W2058154531 @default.
• W1971562495 cites W2087179076 @default.
• W1971562495 cites W2101995865 @default.
• W1971562495 cites W2105376289 @default.
• W1971562495 cites W2107931058 @default.
• W1971562495 cites W2118605519 @default.
• W1971562495 cites W2122289625 @default.
• W1971562495 cites W2139464284 @default.
• W1971562495 cites W2142486051 @default.
• W1971562495 cites W2151859419 @default.
• W1971562495 cites W2154142993 @default.
• W1971562495 cites W2157285286 @default.
• W1971562495 cites W2162760540 @default.
• W1971562495 cites W2164774797 @default.
• W1971562495 cites W2171972386 @default.
• W1971562495 cites W2183688299 @default.
• W1971562495 cites W3093265161 @default.
• W1971562495 doi "https://doi.org/10.1245/s10434-011-1877-y" @default.
• W1971562495 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3892697" @default.
• W1971562495 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21725686" @default.
• W1971562495 hasPublicationYear "2011" @default.
• W1971562495 type Work @default.
• W1971562495 sameAs 1971562495 @default.
• W1971562495 citedByCount "54" @default.
• W1971562495 countsByYear W19715624952012 @default.
• W1971562495 countsByYear W19715624952013 @default.
• W1971562495 countsByYear W19715624952014 @default.
• W1971562495 countsByYear W19715624952015 @default.
• W1971562495 countsByYear W19715624952016 @default.
• W1971562495 countsByYear W19715624952017 @default.
• W1971562495 countsByYear W19715624952018 @default.
• W1971562495 countsByYear W19715624952019 @default.
• W1971562495 countsByYear W19715624952020 @default.
• W1971562495 countsByYear W19715624952021 @default.
• W1971562495 countsByYear W19715624952022 @default.
• W1971562495 countsByYear W19715624952023 @default.
• W1971562495 crossrefType "journal-article" @default.
• W1971562495 hasAuthorship W1971562495A5008654358 @default.
• W1971562495 hasAuthorship W1971562495A5009199118 @default.
• W1971562495 hasAuthorship W1971562495A5032371242 @default.
• W1971562495 hasAuthorship W1971562495A5050528770 @default.
• W1971562495 hasAuthorship W1971562495A5054757298 @default.
• W1971562495 hasAuthorship W1971562495A5061892063 @default.
• W1971562495 hasAuthorship W1971562495A5082828758 @default.
• W1971562495 hasBestOaLocation W19715624952 @default.
• W1971562495 hasConcept C121608353 @default.
• W1971562495 hasConcept C126322002 @default.
• W1971562495 hasConcept C143998085 @default.
• W1971562495 hasConcept C146357865 @default.
• W1971562495 hasConcept C151730666 @default.
• W1971562495 hasConcept C207103383 @default.
• W1971562495 hasConcept C2776694085 @default.
• W1971562495 hasConcept C2778292576 @default.
• W1971562495 hasConcept C2780110267 @default.
• W1971562495 hasConcept C2780140570 @default.
• W1971562495 hasConcept C44249647 @default.
• W1971562495 hasConcept C530470458 @default.
• W1971562495 hasConcept C71924100 @default.
• W1971562495 hasConcept C86803240 @default.
• W1971562495 hasConceptScore W1971562495C121608353 @default.
• W1971562495 hasConceptScore W1971562495C126322002 @default.
• W1971562495 hasConceptScore W1971562495C143998085 @default.
• W1971562495 hasConceptScore W1971562495C146357865 @default.
• W1971562495 hasConceptScore W1971562495C151730666 @default.
• W1971562495 hasConceptScore W1971562495C207103383 @default.
• W1971562495 hasConceptScore W1971562495C2776694085 @default.
• W1971562495 hasConceptScore W1971562495C2778292576 @default.
• W1971562495 hasConceptScore W1971562495C2780110267 @default.
• W1971562495 hasConceptScore W1971562495C2780140570 @default.
• W1971562495 hasConceptScore W1971562495C44249647 @default.
• W1971562495 hasConceptScore W1971562495C530470458 @default.
• W1971562495 hasConceptScore W1971562495C71924100 @default.
• W1971562495 hasConceptScore W1971562495C86803240 @default.
• W1971562495 hasIssue "1" @default.
• W1971562495 hasLocation W19715624951 @default.
• W1971562495 hasLocation W19715624952 @default.
• W1971562495 hasLocation W19715624953 @default.
• W1971562495 hasLocation W19715624954 @default.
• W1971562495 hasOpenAccess W1971562495 @default.
• W1971562495 hasPrimaryLocation W19715624951 @default.
• W1971562495 hasRelatedWork W1255356622 @default.
• W1971562495 hasRelatedWork W2013809648 @default.
• W1971562495 hasRelatedWork W2358701816 @default.

• next