Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971623489> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1971623489 abstract "CD14, the monocyte receptor for lipopolysaccharides (LPS), is an important mediator of inflammatory processes. As the T-159C exchange in the promotor of the CD14 gene was reported to lead to enhanced CD14 expression, this could be a new susceptibility gene for rheumatoid arthritis (RA). We investigated whether this single nucleotide polymorphism (SNP) serves as a risk factor for disease development or has any influence on serological activity parameters of RA or soluble CD14 (sCD14) levels.A total of 130 patients with RA, diagnosed according to the revised American College of Rheumatology (ACR) criteria, and 130 healthy subjects, all Caucasians, were genotyped using polymerase chain reaction (PCR). Genotype frequencies were compared by chi2 analysis.Forty (31%) patients vs. 39 (30%) controls were genotyped CC; 71 (55%) vs. 67 (52%) were heterozygous, and 19 (15%) vs. 24 (19%) showed the TT genotype (p = 0.7). Accordingly, the allele frequency was equally distributed (p = 0.8). There was also no significant difference in genotype distribution between subgroups of patients categorized according to serological activity parameters and sCD14 levels.We found no association between the CD14/C-159T polymorphism and increased risk for the development of RA or serological disease activity parameters or sCD14 levels." @default.
- W1971623489 created "2016-06-24" @default.
- W1971623489 creator A5009261802 @default.
- W1971623489 creator A5040608868 @default.
- W1971623489 creator A5060450395 @default.
- W1971623489 creator A5071626786 @default.
- W1971623489 creator A5076767125 @default.
- W1971623489 date "2006-01-01" @default.
- W1971623489 modified "2023-09-25" @default.
- W1971623489 title "Lack of association of the CD14/C–159T polymorphism with susceptibility and serological activity parameters of rheumatoid arthritis" @default.
- W1971623489 cites W1504603444 @default.
- W1971623489 cites W1982345842 @default.
- W1971623489 cites W1986430553 @default.
- W1971623489 cites W1998266250 @default.
- W1971623489 cites W2006053438 @default.
- W1971623489 cites W2012439992 @default.
- W1971623489 cites W2029157767 @default.
- W1971623489 cites W2057025584 @default.
- W1971623489 cites W2067394045 @default.
- W1971623489 cites W2092591554 @default.
- W1971623489 cites W2093120748 @default.
- W1971623489 cites W2102074039 @default.
- W1971623489 cites W2123333870 @default.
- W1971623489 cites W2152348310 @default.
- W1971623489 doi "https://doi.org/10.1080/03009740500395260" @default.
- W1971623489 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16467036" @default.
- W1971623489 hasPublicationYear "2006" @default.
- W1971623489 type Work @default.
- W1971623489 sameAs 1971623489 @default.
- W1971623489 citedByCount "7" @default.
- W1971623489 countsByYear W19716234892012 @default.
- W1971623489 countsByYear W19716234892013 @default.
- W1971623489 countsByYear W19716234892021 @default.
- W1971623489 crossrefType "journal-article" @default.
- W1971623489 hasAuthorship W1971623489A5009261802 @default.
- W1971623489 hasAuthorship W1971623489A5040608868 @default.
- W1971623489 hasAuthorship W1971623489A5060450395 @default.
- W1971623489 hasAuthorship W1971623489A5071626786 @default.
- W1971623489 hasAuthorship W1971623489A5076767125 @default.
- W1971623489 hasConcept C104317684 @default.
- W1971623489 hasConcept C126322002 @default.
- W1971623489 hasConcept C135763542 @default.
- W1971623489 hasConcept C139275648 @default.
- W1971623489 hasConcept C153209595 @default.
- W1971623489 hasConcept C159654299 @default.
- W1971623489 hasConcept C170493617 @default.
- W1971623489 hasConcept C180754005 @default.
- W1971623489 hasConcept C198451711 @default.
- W1971623489 hasConcept C203014093 @default.
- W1971623489 hasConcept C2776232647 @default.
- W1971623489 hasConcept C2777077863 @default.
- W1971623489 hasConcept C2777575956 @default.
- W1971623489 hasConcept C2778513237 @default.
- W1971623489 hasConcept C45189115 @default.
- W1971623489 hasConcept C54355233 @default.
- W1971623489 hasConcept C71924100 @default.
- W1971623489 hasConcept C86803240 @default.
- W1971623489 hasConcept C90924648 @default.
- W1971623489 hasConceptScore W1971623489C104317684 @default.
- W1971623489 hasConceptScore W1971623489C126322002 @default.
- W1971623489 hasConceptScore W1971623489C135763542 @default.
- W1971623489 hasConceptScore W1971623489C139275648 @default.
- W1971623489 hasConceptScore W1971623489C153209595 @default.
- W1971623489 hasConceptScore W1971623489C159654299 @default.
- W1971623489 hasConceptScore W1971623489C170493617 @default.
- W1971623489 hasConceptScore W1971623489C180754005 @default.
- W1971623489 hasConceptScore W1971623489C198451711 @default.
- W1971623489 hasConceptScore W1971623489C203014093 @default.
- W1971623489 hasConceptScore W1971623489C2776232647 @default.
- W1971623489 hasConceptScore W1971623489C2777077863 @default.
- W1971623489 hasConceptScore W1971623489C2777575956 @default.
- W1971623489 hasConceptScore W1971623489C2778513237 @default.
- W1971623489 hasConceptScore W1971623489C45189115 @default.
- W1971623489 hasConceptScore W1971623489C54355233 @default.
- W1971623489 hasConceptScore W1971623489C71924100 @default.
- W1971623489 hasConceptScore W1971623489C86803240 @default.
- W1971623489 hasConceptScore W1971623489C90924648 @default.
- W1971623489 hasLocation W19716234891 @default.
- W1971623489 hasLocation W19716234892 @default.
- W1971623489 hasOpenAccess W1971623489 @default.
- W1971623489 hasPrimaryLocation W19716234891 @default.
- W1971623489 hasRelatedWork W1853889937 @default.
- W1971623489 hasRelatedWork W2348076134 @default.
- W1971623489 hasRelatedWork W2355028327 @default.
- W1971623489 hasRelatedWork W2356468612 @default.
- W1971623489 hasRelatedWork W2358154819 @default.
- W1971623489 hasRelatedWork W2382289467 @default.
- W1971623489 hasRelatedWork W2591824353 @default.
- W1971623489 hasRelatedWork W2791073779 @default.
- W1971623489 hasRelatedWork W3017659492 @default.
- W1971623489 hasRelatedWork W3029259469 @default.
- W1971623489 isParatext "false" @default.
- W1971623489 isRetracted "false" @default.
- W1971623489 magId "1971623489" @default.
- W1971623489 workType "article" @default.