Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971628181> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W1971628181 endingPage "2438" @default.
- W1971628181 startingPage "2434" @default.
- W1971628181 abstract "Many tumors contain high amounts of the detoxification enzyme glutathione S-transferase P1-1 (GSTP1-1). Elevated levels of GSTP1-1 have also been detected in serum and plasma from patients with gastrointestinal, lung, or head and neck tumors. The authors of this report evaluated the role of GSTP1-1 as a plasma tumor marker in patients with head and neck squamous cell carcinoma (HNSCC) of the larynx, hypopharynx, or oropharnyx and in patients with benign head and neck lesions (BHNL).GSTP1-1 levels were measured in EDTA plasma combined with ethylenediaminetetraacetic acid using a recently developed sensitive and specific sandwich enzyme-linked immunoadsorbent assay. A normal reference level with an upper limit of 21.8 microg GSTP1-1 per liter of plasma was calculated from results obtained with samples from 230 blood donors.Median GSTP1-1 levels in samples from 53 patients with oral/oropharyngeal SCC (10.6 microg/L; range, 3.7-46.1 microg/L), 12 patients with hypopharyngeal SCC (11.9 microg/L; range, 5.2-146.6 microg/L), and 28 patients with laryngeal SCC (14.4 microg/L; range, 6.4-141.5 microg/L) were significantly elevated when compared with plasma GSTP1-1 levels in samples from 45 patients with BHNL (8.1 microg/L; range, 3.3-32.3 microg/L; P < 0.0001, P < 0.01, and P < 0.0001, respectively). However, only 6 of 53 patients (11%) with oral/oropharyngeal SCC, 1 of 12 patients (8%) with hypopharyngeal SCC, and 6 of 28 patients (21%) with laryngeal SCC had plasma GSTP1-1 levels above the upper limit of the normal reference level. Thus, only 13 of 93 patients (14%) with HNSCC had elevated plasma GSTP1-1 levels overall. No significant relation between plasma GSTP1-1 levels and TNM classification of the tumors was observed.GSTP1-1 is not a suitable plasma tumor marker for HNSCC." @default.
- W1971628181 created "2016-06-24" @default.
- W1971628181 creator A5035708680 @default.
- W1971628181 creator A5048880494 @default.
- W1971628181 creator A5053115428 @default.
- W1971628181 creator A5058095802 @default.
- W1971628181 date "1998-06-15" @default.
- W1971628181 modified "2023-10-14" @default.
- W1971628181 title "Plasma glutathioneS-transferase P1-1 levels in patients with head and neck squamous cell carcinoma" @default.
- W1971628181 cites W1973063537 @default.
- W1971628181 cites W1981367979 @default.
- W1971628181 cites W1984863026 @default.
- W1971628181 cites W1991158505 @default.
- W1971628181 cites W2028899869 @default.
- W1971628181 cites W2033580245 @default.
- W1971628181 cites W2047775096 @default.
- W1971628181 cites W2064035407 @default.
- W1971628181 cites W2150118236 @default.
- W1971628181 cites W2153124384 @default.
- W1971628181 cites W2183685355 @default.
- W1971628181 cites W33811216 @default.
- W1971628181 doi "https://doi.org/10.1002/(sici)1097-0142(19980615)82:12<2434::aid-cncr18>3.0.co;2-q" @default.
- W1971628181 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9635537" @default.
- W1971628181 hasPublicationYear "1998" @default.
- W1971628181 type Work @default.
- W1971628181 sameAs 1971628181 @default.
- W1971628181 citedByCount "14" @default.
- W1971628181 countsByYear W19716281812012 @default.
- W1971628181 countsByYear W19716281812014 @default.
- W1971628181 countsByYear W19716281812019 @default.
- W1971628181 crossrefType "journal-article" @default.
- W1971628181 hasAuthorship W1971628181A5035708680 @default.
- W1971628181 hasAuthorship W1971628181A5048880494 @default.
- W1971628181 hasAuthorship W1971628181A5053115428 @default.
- W1971628181 hasAuthorship W1971628181A5058095802 @default.
- W1971628181 hasBestOaLocation W19716281811 @default.
- W1971628181 hasConcept C121608353 @default.
- W1971628181 hasConcept C126322002 @default.
- W1971628181 hasConcept C141071460 @default.
- W1971628181 hasConcept C142724271 @default.
- W1971628181 hasConcept C176674119 @default.
- W1971628181 hasConcept C2776530083 @default.
- W1971628181 hasConcept C2776694085 @default.
- W1971628181 hasConcept C2776833033 @default.
- W1971628181 hasConcept C2777546739 @default.
- W1971628181 hasConcept C2778496288 @default.
- W1971628181 hasConcept C2780474809 @default.
- W1971628181 hasConcept C2994460389 @default.
- W1971628181 hasConcept C71924100 @default.
- W1971628181 hasConcept C90924648 @default.
- W1971628181 hasConceptScore W1971628181C121608353 @default.
- W1971628181 hasConceptScore W1971628181C126322002 @default.
- W1971628181 hasConceptScore W1971628181C141071460 @default.
- W1971628181 hasConceptScore W1971628181C142724271 @default.
- W1971628181 hasConceptScore W1971628181C176674119 @default.
- W1971628181 hasConceptScore W1971628181C2776530083 @default.
- W1971628181 hasConceptScore W1971628181C2776694085 @default.
- W1971628181 hasConceptScore W1971628181C2776833033 @default.
- W1971628181 hasConceptScore W1971628181C2777546739 @default.
- W1971628181 hasConceptScore W1971628181C2778496288 @default.
- W1971628181 hasConceptScore W1971628181C2780474809 @default.
- W1971628181 hasConceptScore W1971628181C2994460389 @default.
- W1971628181 hasConceptScore W1971628181C71924100 @default.
- W1971628181 hasConceptScore W1971628181C90924648 @default.
- W1971628181 hasIssue "12" @default.
- W1971628181 hasLocation W19716281811 @default.
- W1971628181 hasLocation W19716281812 @default.
- W1971628181 hasOpenAccess W1971628181 @default.
- W1971628181 hasPrimaryLocation W19716281811 @default.
- W1971628181 hasRelatedWork W1857129469 @default.
- W1971628181 hasRelatedWork W1968208170 @default.
- W1971628181 hasRelatedWork W1989155114 @default.
- W1971628181 hasRelatedWork W1994459365 @default.
- W1971628181 hasRelatedWork W2146329765 @default.
- W1971628181 hasRelatedWork W2335154415 @default.
- W1971628181 hasRelatedWork W2887381043 @default.
- W1971628181 hasRelatedWork W3013149092 @default.
- W1971628181 hasRelatedWork W3181900860 @default.
- W1971628181 hasRelatedWork W4306668428 @default.
- W1971628181 hasVolume "82" @default.
- W1971628181 isParatext "false" @default.
- W1971628181 isRetracted "false" @default.
- W1971628181 magId "1971628181" @default.
- W1971628181 workType "article" @default.