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- W1971644211 abstract "We report a case of severe AVP three weeks following the administration of infliximab for the treatment of Crohn's disease (CD). Since the introduction of tumor necrosis factor-alpha (TNF-α) antagonists, various microbiologic agents have been reported to cause pneumonia following their administration. To our knowledge, AVP following therapy with TNF-α antagonists has not been reported in English literature. We present a brief review of the mechanism of action of TNF-α antagonists and their ability to predispose to various infections including viral pneumonia by interfering with the immune response. We report a case of severe AVP three weeks following the administration of infliximab for the treatment of Crohn's disease (CD). Since the introduction of tumor necrosis factor-alpha (TNF-α) antagonists, various microbiologic agents have been reported to cause pneumonia following their administration. To our knowledge, AVP following therapy with TNF-α antagonists has not been reported in English literature. We present a brief review of the mechanism of action of TNF-α antagonists and their ability to predispose to various infections including viral pneumonia by interfering with the immune response." @default.
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- W1971644211 date "2007-01-01" @default.
- W1971644211 modified "2023-10-16" @default.
- W1971644211 title "Severe adenovirus pneumonia (AVP) following infliximab infusion for the treatment of Crohn's disease" @default.
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- W1971644211 doi "https://doi.org/10.1016/j.jinf.2006.03.025" @default.
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