FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971647531> ?p ?o ?g. }

• W1971647531 endingPage "109" @default.
• W1971647531 startingPage "102" @default.
• W1971647531 abstract "We demonstrated that p53-deficiency is sufficient for immortalization of fetal uterine cells. In the present study, we further extended our previous observations to prostate tissues from a young p53-deficient adult mouse.Cell lines were established from the ventral prostate of a p53-deficient male mouse and maintained in medium containing 10% heat-inactivated fetal calf serum supplemented with insulin (10 microg/ml), transferrin (10 microg/ml), cholera toxin (10 ng/ml), and selenium (10(-8) M).Pro9ad, one of the lines established, exhibits a typical epithelial morphology in culture. Despite the possession of androgen receptors, the growth of Pro9ad was not stimulated by 5alpha-dihydrotestosterone. Hepatocyte growth factor (HGF) slightly stimulated proliferation, whereas fibroblast growth factor-1 (FGF-1), keratinocyte growth factor (KGF), and platelet-derived growth factor AB (PDGF-AB) had no stimulating effect on growth. However, FGF-2, epidermal growth factor (EGF), and insulin-like growth factor-1 (IGF-1) accelerated proliferation in a dose-dependent manner. EGF and IGF-1 additively stimulated growth.These results suggest that Pro9ad shares characteristics in common with primary prostatic epithelial cells despite p53-deficiency, and that p53-deficiency alone allows establishment of clonal cell lines of the prostate epithelium. Furthermore, the prostates of p53-deficient mice are useful sources for obtaining cell lines." @default.
• W1971647531 created "2016-06-24" @default.
• W1971647531 creator A5010103072 @default.
• W1971647531 creator A5022819913 @default.
• W1971647531 creator A5059219079 @default.
• W1971647531 creator A5085974439 @default.
• W1971647531 date "1998-07-01" @default.
• W1971647531 modified "2023-09-23" @default.
• W1971647531 title "Establishment of prostatic cell line “Pro9ad” from a p53-deficient mouse" @default.
• W1971647531 cites W1930373062 @default.
• W1971647531 cites W1964533970 @default.
• W1971647531 cites W1965768875 @default.
• W1971647531 cites W1974667009 @default.
• W1971647531 cites W1978603267 @default.
• W1971647531 cites W1978701193 @default.
• W1971647531 cites W1982997994 @default.
• W1971647531 cites W1983360399 @default.
• W1971647531 cites W1984440848 @default.
• W1971647531 cites W1986179131 @default.
• W1971647531 cites W1987609643 @default.
• W1971647531 cites W1989924636 @default.
• W1971647531 cites W2004794055 @default.
• W1971647531 cites W2006199359 @default.
• W1971647531 cites W2007905997 @default.
• W1971647531 cites W2021890356 @default.
• W1971647531 cites W2032196515 @default.
• W1971647531 cites W2036246146 @default.
• W1971647531 cites W2040914101 @default.
• W1971647531 cites W2061686178 @default.
• W1971647531 cites W2066570340 @default.
• W1971647531 cites W2067847877 @default.
• W1971647531 cites W2068776422 @default.
• W1971647531 cites W2070769230 @default.
• W1971647531 cites W2070885297 @default.
• W1971647531 cites W2073292917 @default.
• W1971647531 cites W2084595135 @default.
• W1971647531 cites W2085698470 @default.
• W1971647531 cites W2088775512 @default.
• W1971647531 cites W2089730410 @default.
• W1971647531 cites W2092871290 @default.
• W1971647531 cites W2094912241 @default.
• W1971647531 cites W2095378062 @default.
• W1971647531 cites W2100843929 @default.
• W1971647531 cites W2151477904 @default.
• W1971647531 cites W4253480793 @default.
• W1971647531 cites W90893581 @default.
• W1971647531 doi "https://doi.org/10.1002/(sici)1097-0045(19980701)36:2<102::aid-pros5>3.0.co;2-k" @default.
• W1971647531 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9655262" @default.
• W1971647531 hasPublicationYear "1998" @default.
• W1971647531 type Work @default.
• W1971647531 sameAs 1971647531 @default.
• W1971647531 citedByCount "17" @default.
• W1971647531 crossrefType "journal-article" @default.
• W1971647531 hasAuthorship W1971647531A5010103072 @default.
• W1971647531 hasAuthorship W1971647531A5022819913 @default.
• W1971647531 hasAuthorship W1971647531A5059219079 @default.
• W1971647531 hasAuthorship W1971647531A5085974439 @default.
• W1971647531 hasConcept C121608353 @default.
• W1971647531 hasConcept C126322002 @default.
• W1971647531 hasConcept C134018914 @default.
• W1971647531 hasConcept C170493617 @default.
• W1971647531 hasConcept C2775960820 @default.
• W1971647531 hasConcept C2776235491 @default.
• W1971647531 hasConcept C2776362946 @default.
• W1971647531 hasConcept C2776996007 @default.
• W1971647531 hasConcept C2777911890 @default.
• W1971647531 hasConcept C2778615670 @default.
• W1971647531 hasConcept C2779881493 @default.
• W1971647531 hasConcept C502942594 @default.
• W1971647531 hasConcept C529295009 @default.
• W1971647531 hasConcept C54355233 @default.
• W1971647531 hasConcept C6045943 @default.
• W1971647531 hasConcept C62112901 @default.
• W1971647531 hasConcept C71315377 @default.
• W1971647531 hasConcept C71924100 @default.
• W1971647531 hasConcept C74373430 @default.
• W1971647531 hasConcept C81885089 @default.
• W1971647531 hasConcept C86803240 @default.
• W1971647531 hasConceptScore W1971647531C121608353 @default.
• W1971647531 hasConceptScore W1971647531C126322002 @default.
• W1971647531 hasConceptScore W1971647531C134018914 @default.
• W1971647531 hasConceptScore W1971647531C170493617 @default.
• W1971647531 hasConceptScore W1971647531C2775960820 @default.
• W1971647531 hasConceptScore W1971647531C2776235491 @default.
• W1971647531 hasConceptScore W1971647531C2776362946 @default.
• W1971647531 hasConceptScore W1971647531C2776996007 @default.
• W1971647531 hasConceptScore W1971647531C2777911890 @default.
• W1971647531 hasConceptScore W1971647531C2778615670 @default.
• W1971647531 hasConceptScore W1971647531C2779881493 @default.
• W1971647531 hasConceptScore W1971647531C502942594 @default.
• W1971647531 hasConceptScore W1971647531C529295009 @default.
• W1971647531 hasConceptScore W1971647531C54355233 @default.
• W1971647531 hasConceptScore W1971647531C6045943 @default.
• W1971647531 hasConceptScore W1971647531C62112901 @default.
• W1971647531 hasConceptScore W1971647531C71315377 @default.
• W1971647531 hasConceptScore W1971647531C71924100 @default.
• W1971647531 hasConceptScore W1971647531C74373430 @default.
• W1971647531 hasConceptScore W1971647531C81885089 @default.

• next