Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971674711> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1971674711 endingPage "92" @default.
- W1971674711 startingPage "87" @default.
- W1971674711 abstract "Ibogaine, an indolalkylamine, has been proposed for use in treating stimulant addiction. In the present study we sought to determine if ibogaine had any effects on the neurochemical and motor changes induced by D-amphetamine that would substantiate the anti-addictive claim. Ibogaine (40 mg/kg, i.p.) injected 19 h prior to a D-amphetamine challenge (1.25 mg/kg, i.p.) potentiated the expected rise in extracellular dopamine levels in the striatum and in the nucleus accumbens, as measured by microdialysis in freely moving rats. Using photocell activity cages, the same ibogaine pretreatment enhanced the stimulatory motor effects induced by a wide range of D-amphetamine doses (0.625, 1.25, 2.5 or 5 mg/kg, i.p.). These findings suggest that ibogaine might increase the reinforcing efficacy of D-amphetamine. However, since high doses of D-amphetamine can be aversive, the potentiation of D-amphetamine's effects by ibogaine might also lead to a decrease in the reinforcing efficacy of D-amphetamine." @default.
- W1971674711 created "2016-06-24" @default.
- W1971674711 creator A5034237660 @default.
- W1971674711 creator A5078434120 @default.
- W1971674711 creator A5089897405 @default.
- W1971674711 date "1992-05-01" @default.
- W1971674711 modified "2023-10-03" @default.
- W1971674711 title "Interaction of ibogaine and d-amphetamine: in vivo microdialysis and motor behavior in rats" @default.
- W1971674711 cites W1969904644 @default.
- W1971674711 cites W1977541944 @default.
- W1971674711 cites W1982641194 @default.
- W1971674711 cites W1990819039 @default.
- W1971674711 cites W2005327856 @default.
- W1971674711 cites W2005690521 @default.
- W1971674711 cites W2011658876 @default.
- W1971674711 cites W2020860451 @default.
- W1971674711 cites W2022395708 @default.
- W1971674711 cites W2023163510 @default.
- W1971674711 cites W2025495736 @default.
- W1971674711 cites W2034611322 @default.
- W1971674711 cites W2040542735 @default.
- W1971674711 cites W2041742732 @default.
- W1971674711 cites W2044892899 @default.
- W1971674711 cites W2047132391 @default.
- W1971674711 cites W2060996423 @default.
- W1971674711 cites W2069132032 @default.
- W1971674711 cites W2073069459 @default.
- W1971674711 cites W2077726925 @default.
- W1971674711 cites W2090229163 @default.
- W1971674711 cites W2122592499 @default.
- W1971674711 cites W2139256345 @default.
- W1971674711 cites W2146563642 @default.
- W1971674711 doi "https://doi.org/10.1016/0006-8993(92)90745-u" @default.
- W1971674711 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1623410" @default.
- W1971674711 hasPublicationYear "1992" @default.
- W1971674711 type Work @default.
- W1971674711 sameAs 1971674711 @default.
- W1971674711 citedByCount "51" @default.
- W1971674711 countsByYear W19716747112014 @default.
- W1971674711 countsByYear W19716747112016 @default.
- W1971674711 countsByYear W19716747112017 @default.
- W1971674711 countsByYear W19716747112021 @default.
- W1971674711 crossrefType "journal-article" @default.
- W1971674711 hasAuthorship W1971674711A5034237660 @default.
- W1971674711 hasAuthorship W1971674711A5078434120 @default.
- W1971674711 hasAuthorship W1971674711A5089897405 @default.
- W1971674711 hasConcept C15744967 @default.
- W1971674711 hasConcept C169760540 @default.
- W1971674711 hasConcept C185592680 @default.
- W1971674711 hasConcept C25876315 @default.
- W1971674711 hasConcept C2776552330 @default.
- W1971674711 hasConcept C2777193897 @default.
- W1971674711 hasConcept C2780062018 @default.
- W1971674711 hasConcept C2780557958 @default.
- W1971674711 hasConcept C50156730 @default.
- W1971674711 hasConcept C513476851 @default.
- W1971674711 hasConcept C71924100 @default.
- W1971674711 hasConcept C98274493 @default.
- W1971674711 hasConceptScore W1971674711C15744967 @default.
- W1971674711 hasConceptScore W1971674711C169760540 @default.
- W1971674711 hasConceptScore W1971674711C185592680 @default.
- W1971674711 hasConceptScore W1971674711C25876315 @default.
- W1971674711 hasConceptScore W1971674711C2776552330 @default.
- W1971674711 hasConceptScore W1971674711C2777193897 @default.
- W1971674711 hasConceptScore W1971674711C2780062018 @default.
- W1971674711 hasConceptScore W1971674711C2780557958 @default.
- W1971674711 hasConceptScore W1971674711C50156730 @default.
- W1971674711 hasConceptScore W1971674711C513476851 @default.
- W1971674711 hasConceptScore W1971674711C71924100 @default.
- W1971674711 hasConceptScore W1971674711C98274493 @default.
- W1971674711 hasIssue "1" @default.
- W1971674711 hasLocation W19716747111 @default.
- W1971674711 hasLocation W19716747112 @default.
- W1971674711 hasOpenAccess W1971674711 @default.
- W1971674711 hasPrimaryLocation W19716747111 @default.
- W1971674711 hasRelatedWork W1201812235 @default.
- W1971674711 hasRelatedWork W1970211188 @default.
- W1971674711 hasRelatedWork W1972873401 @default.
- W1971674711 hasRelatedWork W1982383406 @default.
- W1971674711 hasRelatedWork W2011351971 @default.
- W1971674711 hasRelatedWork W2055207238 @default.
- W1971674711 hasRelatedWork W2093185137 @default.
- W1971674711 hasRelatedWork W2095849459 @default.
- W1971674711 hasRelatedWork W2967611747 @default.
- W1971674711 hasRelatedWork W3034142565 @default.
- W1971674711 hasVolume "579" @default.
- W1971674711 isParatext "false" @default.
- W1971674711 isRetracted "false" @default.
- W1971674711 magId "1971674711" @default.
- W1971674711 workType "article" @default.