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• W1971794055 abstract "The activity of the noradrenergic marker enzyme dopamine-beta-hydroxylase was measured in brains removed postmortem from control patients and patients with Alzheimer's disease. Enzyme activity was decreased in the frontal and temporal cortices and hippocampus in patients with Alzheimer's disease, but was within the normal range in patients with depression, multiinfarct dementia, and terminal coma. The decrease in enzyme activity in Alzheimer's disease may reflect an abnormality of cortical noradrenergic fibres in some patients with the disease." @default.
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• W1971794055 date "1981-01-10" @default.
• W1971794055 modified "2023-09-26" @default.
• W1971794055 title "Reduced dopamine-beta-hydroxylase activity in Alzheimer's disease" @default.
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• W1971794055 doi "https://doi.org/10.1136/bmj.282.6258.93" @default.
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