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- W1971815053 abstract "Summary Angiogenesis is a biological process by which new capillaries are formed and it occurs in many physiological and pathological conditions. It is controlled by the net balance between molecules that have positive and negative regulatory activity and this concept had led to the notion of the ‘angiogenic switch’, depending on an increased production of one or more of the positive regulators of angiogenesis. Numerous inducers of angiogenesis have been identified and this review offers a historical account of the relevant literature concerning the discovery of one of the best characterized angiogenic factors, namely vascular endothelial growth factor (VEGF)/vascular permeability factor. Moreover, different strategies, designed to stimulate and to inhibit VEGF production in the context of several potential therapeutical implications, are discussed." @default.
- W1971815053 created "2016-06-24" @default.
- W1971815053 creator A5054370212 @default.
- W1971815053 date "2005-01-24" @default.
- W1971815053 modified "2023-10-17" @default.
- W1971815053 title "The crucial role of vascular permeability factor/vascular endothelial growth factor in angiogenesis: a historical review" @default.
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- W1971815053 doi "https://doi.org/10.1111/j.1365-2141.2004.05291.x" @default.
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