FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971815482> ?p ?o ?g. }

• W1971815482 endingPage "37" @default.
• W1971815482 startingPage "29" @default.
• W1971815482 abstract "This study was designed to determine the effect of Mangifera indica flowers decoction, on the acute and subacute models of induced ulcer in mice and rats. A single oral administration of the aqueous decoction (AD) from M. indica up to a dose of 5 g/kg, p.o. did not produce any signs or symptom of toxicity in the treated animals. The oral pre-treatment with AD (250, 500 and 1000 mg/kg) in rats with gastric lesions induced by ethanol, decreased the gastric lesions from 89.0 ± 6.71 (control group) to 9.25 ± 2.75, 4.50 ± 3.30 and 0, respectively. Pretreatment with AD (250, 500 and 1000 mg/kg) to mice with HCl/ethanol- or stress-induced gastric lesions resulted in a dose-dependent significant decrease of lesion index. In the piroxicam-induced gastric lesions, the gastroprotective effect of AD was reducing with the increase of the AD dose. In the pylorus-ligature, AD (p.o.) significantly decreased the acid output indicating the antisecretory property involved in the gastroprotective effect of M. indica. Treatment with AD during 14 consecutive days significantly accelerated the healing process in subacute gastric ulcer induced by acetic acid in rats. Pretreatment with N-nitro-l-arginine methyl ester (l-NAME), an inhibitor of NO-synthase, did not abolish the gastroprotective effects (99% with saline versus 80% with l-NAME) of AD against ethanol-induced gastric lesions. Pretreatment with N-ethylmaleimide (NEM), a blocker of endogenous sulphydryl group, significantly abolished the protective effects of AD against ethanol-induced gastric ulcers (95% with saline versus 47% with NEM). Phytochemical screening showed the presence of steroids, triterpenes, phenolic compounds and flavonoids. Estimation of the global polyphenol content in the AD was performed by Folin–Ciocalteu method and showed approximately 53% of total phenolic on this extract. These findings indicate the potential gastroprotective and ulcer-healing properties of aqueous decoction of M. indica flowers and further support its popular use in gastrointestinal disorders in Caribbean." @default.
• W1971815482 created "2016-06-24" @default.
• W1971815482 creator A5001869462 @default.
• W1971815482 creator A5008227794 @default.
• W1971815482 creator A5019982779 @default.
• W1971815482 creator A5022870772 @default.
• W1971815482 creator A5033216377 @default.
• W1971815482 creator A5055645047 @default.
• W1971815482 creator A5061814345 @default.
• W1971815482 creator A5064319654 @default.
• W1971815482 creator A5091776752 @default.
• W1971815482 date "2006-06-01" @default.
• W1971815482 modified "2023-10-06" @default.
• W1971815482 title "Can the aqueous decoction of mango flowers be used as an antiulcer agent?" @default.
• W1971815482 cites W156921158 @default.
• W1971815482 cites W1614427627 @default.
• W1971815482 cites W1966038976 @default.
• W1971815482 cites W1968609884 @default.
• W1971815482 cites W1969029931 @default.
• W1971815482 cites W1969552356 @default.
• W1971815482 cites W1973131192 @default.
• W1971815482 cites W1976773412 @default.
• W1971815482 cites W1976822147 @default.
• W1971815482 cites W1983012176 @default.
• W1971815482 cites W1989377628 @default.
• W1971815482 cites W1996772650 @default.
• W1971815482 cites W2003177525 @default.
• W1971815482 cites W2004310698 @default.
• W1971815482 cites W2006813311 @default.
• W1971815482 cites W2008633703 @default.
• W1971815482 cites W2020371828 @default.
• W1971815482 cites W2022925425 @default.
• W1971815482 cites W2033135953 @default.
• W1971815482 cites W2034448197 @default.
• W1971815482 cites W2046132421 @default.
• W1971815482 cites W2047712894 @default.
• W1971815482 cites W2048999544 @default.
• W1971815482 cites W2067123786 @default.
• W1971815482 cites W2072133635 @default.
• W1971815482 cites W2095839624 @default.
• W1971815482 cites W2143702981 @default.
• W1971815482 cites W2147417552 @default.
• W1971815482 cites W2163095815 @default.
• W1971815482 cites W2320086384 @default.
• W1971815482 cites W2328338 @default.
• W1971815482 cites W2406105148 @default.
• W1971815482 doi "https://doi.org/10.1016/j.jep.2005.11.032" @default.
• W1971815482 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16500058" @default.
• W1971815482 hasPublicationYear "2006" @default.
• W1971815482 type Work @default.
• W1971815482 sameAs 1971815482 @default.
• W1971815482 citedByCount "70" @default.
• W1971815482 countsByYear W19718154822012 @default.
• W1971815482 countsByYear W19718154822013 @default.
• W1971815482 countsByYear W19718154822014 @default.
• W1971815482 countsByYear W19718154822015 @default.
• W1971815482 countsByYear W19718154822016 @default.
• W1971815482 countsByYear W19718154822017 @default.
• W1971815482 countsByYear W19718154822018 @default.
• W1971815482 countsByYear W19718154822019 @default.
• W1971815482 countsByYear W19718154822020 @default.
• W1971815482 countsByYear W19718154822021 @default.
• W1971815482 countsByYear W19718154822022 @default.
• W1971815482 countsByYear W19718154822023 @default.
• W1971815482 crossrefType "journal-article" @default.
• W1971815482 hasAuthorship W1971815482A5001869462 @default.
• W1971815482 hasAuthorship W1971815482A5008227794 @default.
• W1971815482 hasAuthorship W1971815482A5019982779 @default.
• W1971815482 hasAuthorship W1971815482A5022870772 @default.
• W1971815482 hasAuthorship W1971815482A5033216377 @default.
• W1971815482 hasAuthorship W1971815482A5055645047 @default.
• W1971815482 hasAuthorship W1971815482A5061814345 @default.
• W1971815482 hasAuthorship W1971815482A5064319654 @default.
• W1971815482 hasAuthorship W1971815482A5091776752 @default.
• W1971815482 hasConcept C126322002 @default.
• W1971815482 hasConcept C142724271 @default.
• W1971815482 hasConcept C144027150 @default.
• W1971815482 hasConcept C185592680 @default.
• W1971815482 hasConcept C190409667 @default.
• W1971815482 hasConcept C204787440 @default.
• W1971815482 hasConcept C2777056448 @default.
• W1971815482 hasConcept C2777397205 @default.
• W1971815482 hasConcept C2777498785 @default.
• W1971815482 hasConcept C2778139025 @default.
• W1971815482 hasConcept C2779422922 @default.
• W1971815482 hasConcept C2779969877 @default.
• W1971815482 hasConcept C2780073392 @default.
• W1971815482 hasConcept C2780161600 @default.
• W1971815482 hasConcept C2781429666 @default.
• W1971815482 hasConcept C2781443798 @default.
• W1971815482 hasConcept C55493867 @default.
• W1971815482 hasConcept C556039675 @default.
• W1971815482 hasConcept C71924100 @default.
• W1971815482 hasConcept C86803240 @default.
• W1971815482 hasConcept C98274493 @default.
• W1971815482 hasConceptScore W1971815482C126322002 @default.
• W1971815482 hasConceptScore W1971815482C142724271 @default.
• W1971815482 hasConceptScore W1971815482C144027150 @default.

• next