FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971828356> ?p ?o ?g. }

• W1971828356 endingPage "528" @default.
• W1971828356 startingPage "519" @default.
• W1971828356 abstract "Medial temporal epilepsy (MTLE) is associated with extrahippocampal brain atrophy. The mechanisms underlying brain damage in MTLE are unknown. Seizures may lead to neuronal damage, but another possible explanation is deafferentation from loss of hippocampal connections. This study aimed to investigate the relationship between hippocampal deafferentation and brain atrophy in MTLE.Three different MRI studies were performed involving 23 patients with unilateral MTLE (8 left and 15 right) and 34 healthy controls: (1) voxel-based morphometry (VBM), (2) diffusion tensor imaging (DTI) and (3) probabilistic tractography (PT). VBM was employed to define differences in regional gray matter volume (GMV) between controls and patients. Voxel-wise analyses of DTI evaluated differences in fractional anisotropy (FA), mean diffusivity (MD) and hippocampal PT. Z-scores were computed for regions-of-interest (ROI) GMV and peri-hippocampal FA and MD (to quantify hippocampal fiber integrity). The relationship between hippocampal deafferentation and regional GMV was investigated through the association between ROI Z scores and hippocampal fiber integrity.Patients with MTLE exhibited a significant reduction in GMV and FA in perihippocampal and limbic areas. There was a decrease in hippocampal PT in patients with MTLE in limbic areas. A significant relationship between loss of hippocampal connections and regional GMV atrophy was found involving the putamen, pallidum, middle and inferior temporal areas, amygdala and ceberellar hemisphere.There is a relationship between hippocampal disconnection and regional brain atrophy in MTLE. These results indicate that hippocampal deafferentation plays a contributory role in extrahippocampal brain damage in MTLE." @default.
• W1971828356 created "2016-06-24" @default.
• W1971828356 creator A5004519450 @default.
• W1971828356 creator A5015398638 @default.
• W1971828356 creator A5021099852 @default.
• W1971828356 creator A5044113537 @default.
• W1971828356 creator A5051033644 @default.
• W1971828356 creator A5051697835 @default.
• W1971828356 creator A5077230679 @default.
• W1971828356 creator A5079405130 @default.
• W1971828356 creator A5081481515 @default.
• W1971828356 creator A5081925220 @default.
• W1971828356 date "2010-04-01" @default.
• W1971828356 modified "2023-09-23" @default.
• W1971828356 title "Extrahippocampal gray matter loss and hippocampal deafferentation in patients with temporal lobe epilepsy" @default.
• W1971828356 cites W1968962031 @default.
• W1971828356 cites W1978331472 @default.
• W1971828356 cites W1981898270 @default.
• W1971828356 cites W1984106334 @default.
• W1971828356 cites W1984486655 @default.
• W1971828356 cites W1994572404 @default.
• W1971828356 cites W1997211315 @default.
• W1971828356 cites W2000036923 @default.
• W1971828356 cites W2032152886 @default.
• W1971828356 cites W2038479991 @default.
• W1971828356 cites W2041216092 @default.
• W1971828356 cites W2053384222 @default.
• W1971828356 cites W2058046532 @default.
• W1971828356 cites W2061124379 @default.
• W1971828356 cites W2070066223 @default.
• W1971828356 cites W2071928207 @default.
• W1971828356 cites W2078690270 @default.
• W1971828356 cites W2090966823 @default.
• W1971828356 cites W2090991191 @default.
• W1971828356 cites W2106485269 @default.
• W1971828356 cites W2127623225 @default.
• W1971828356 cites W2134273344 @default.
• W1971828356 cites W2147146794 @default.
• W1971828356 cites W2167527477 @default.
• W1971828356 cites W2173317214 @default.
• W1971828356 cites W4230920194 @default.
• W1971828356 cites W4242041782 @default.
• W1971828356 doi "https://doi.org/10.1111/j.1528-1167.2009.02506.x" @default.
• W1971828356 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2855766" @default.
• W1971828356 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20163442" @default.
• W1971828356 hasPublicationYear "2010" @default.
• W1971828356 type Work @default.
• W1971828356 sameAs 1971828356 @default.
• W1971828356 citedByCount "120" @default.
• W1971828356 countsByYear W19718283562012 @default.
• W1971828356 countsByYear W19718283562013 @default.
• W1971828356 countsByYear W19718283562014 @default.
• W1971828356 countsByYear W19718283562015 @default.
• W1971828356 countsByYear W19718283562016 @default.
• W1971828356 countsByYear W19718283562017 @default.
• W1971828356 countsByYear W19718283562018 @default.
• W1971828356 countsByYear W19718283562019 @default.
• W1971828356 countsByYear W19718283562020 @default.
• W1971828356 countsByYear W19718283562021 @default.
• W1971828356 countsByYear W19718283562022 @default.
• W1971828356 countsByYear W19718283562023 @default.
• W1971828356 crossrefType "journal-article" @default.
• W1971828356 hasAuthorship W1971828356A5004519450 @default.
• W1971828356 hasAuthorship W1971828356A5015398638 @default.
• W1971828356 hasAuthorship W1971828356A5021099852 @default.
• W1971828356 hasAuthorship W1971828356A5044113537 @default.
• W1971828356 hasAuthorship W1971828356A5051033644 @default.
• W1971828356 hasAuthorship W1971828356A5051697835 @default.
• W1971828356 hasAuthorship W1971828356A5077230679 @default.
• W1971828356 hasAuthorship W1971828356A5079405130 @default.
• W1971828356 hasAuthorship W1971828356A5081481515 @default.
• W1971828356 hasAuthorship W1971828356A5081925220 @default.
• W1971828356 hasBestOaLocation W19718283561 @default.
• W1971828356 hasConcept C126838900 @default.
• W1971828356 hasConcept C142724271 @default.
• W1971828356 hasConcept C143409427 @default.
• W1971828356 hasConcept C148762608 @default.
• W1971828356 hasConcept C149550507 @default.
• W1971828356 hasConcept C15744967 @default.
• W1971828356 hasConcept C169760540 @default.
• W1971828356 hasConcept C200134340 @default.
• W1971828356 hasConcept C2776464000 @default.
• W1971828356 hasConcept C2777597344 @default.
• W1971828356 hasConcept C2778186239 @default.
• W1971828356 hasConcept C2778499278 @default.
• W1971828356 hasConcept C2779714222 @default.
• W1971828356 hasConcept C2781099131 @default.
• W1971828356 hasConcept C2781161787 @default.
• W1971828356 hasConcept C2781172350 @default.
• W1971828356 hasConcept C2781192897 @default.
• W1971828356 hasConcept C71924100 @default.
• W1971828356 hasConcept C89916169 @default.
• W1971828356 hasConceptScore W1971828356C126838900 @default.
• W1971828356 hasConceptScore W1971828356C142724271 @default.
• W1971828356 hasConceptScore W1971828356C143409427 @default.
• W1971828356 hasConceptScore W1971828356C148762608 @default.
• W1971828356 hasConceptScore W1971828356C149550507 @default.
• W1971828356 hasConceptScore W1971828356C15744967 @default.

• next