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- W1971896866 abstract "Technectium (Tc99m) iminodiacetic acid (IDA) compounds have replaced 1131 Rose Bengal for hepatobiliary imaging. The primary usefulness in a pediatric population is to confirm patency of the biliary tract. Since June 1981 51 studies have been done on 39 patients; 36 were less than 20 weeks old at the time of first study. The infants were fasted 3 to 6 hours prior to IV Tc99m disIDA (0.1 mCi/K or 1 mCi total) given with the infant supine beneath a gamma camera. Continuous images of the abdomen were obtained for 1 hour, then anterior and posterior images at 2 to 4 hour intervals as necessary. Bilirubin levels and a clinical summary were available for each patient. Of 10 patients (7F, 3M) who proved to have biliary atresia (8) or hypoplasia (2) none excreted IDA into the gut. Of 17 (15M, 2F) with neonatal hepatitis 13 excreted IDA via the biliary tract. Of 9 infants with a variety of congenital defects only the three with cystic fibrosis failed to show excretion into gut. The level of direct bilirubinemia 1.0 to 13.7 (mean 4.8 mg%) was not different in the three groups. The mean CTT level was highest for biliary atresia patients; however, several infants in the other groups excreted IDA with GTT levels over 1000. Improved quality of images and lowered radiation exposure have made scintigraphy with Tc99m IDA compounds a sensitive test to assess hepatobiliary patency in infants and children with direct hyperbilirubinemia. Patients with resolving cholestasis due to a variety of causes including “neonatal hepatitis” can safely be studied." @default.
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- W1971896866 date "1984-09-01" @default.
- W1971896866 modified "2023-10-18" @default.
- W1971896866 title "HEPATOBILIARY SCINTIGRAPHY IN CHILDREN" @default.
- W1971896866 doi "https://doi.org/10.1097/00003072-198409001-00003" @default.
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