Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971970107> ?p ?o ?g. }
Showing items 1 to 54 of
54
with 100 items per page.
- W1971970107 abstract "New techniques and approaches to cellular analysis being developed at the Los Alamos National Flow Cytometry Resource can be divided into those that improve sensitivity and those that move the technology into new areas by refining existing approaches. An example of the first category is a flow cytometric system capable of measuring the phase shift of fluorescence emitted by fluorophors bound to cells is being assembled. This phase sensitive cytometer is be capable of quantifying fluorescence life time on a cell-by-cell basis as well as using the phase sensitive detection to separate fluorescence emissions that overlap spectrally but have different lifetimes. A Fourier transform flow cytometer capable of measuring the fluorescence emission spectrum of individual labeled cells at rates approaching several hundred per second is also in the new technology category. The current implementation is capable of resolving the visible region of the spectrum into 8 bands. With this instrument, it is possible to resolve the contributions of fluorophors with overlapping emission spectra and to determine the emission spectra of dyes such as calcium concentration indicators that are sensitive to the physiological environment. Flow cytometric techniques have been refined to the point that it is possible to detect individual fluorescentmore » molecules in solution as they flow past a laser beam. This capability has lead to a rapid DNA sequencing project. The goal of the project is to develop a technique that is capable of sequencing long strands of DNA (40,000 kb) at a rate of between 100 and 1,000 bases per second.« less" @default.
- W1971970107 created "2016-06-24" @default.
- W1971970107 creator A5003281170 @default.
- W1971970107 creator A5028187863 @default.
- W1971970107 creator A5036729951 @default.
- W1971970107 creator A5057583779 @default.
- W1971970107 creator A5081430818 @default.
- W1971970107 creator A5085135656 @default.
- W1971970107 creator A5089735473 @default.
- W1971970107 date "1993-06-24" @default.
- W1971970107 modified "2023-09-23" @default.
- W1971970107 title "<title>Ultrasensitive flow cytometric analyses</title>" @default.
- W1971970107 doi "https://doi.org/10.1117/12.146722" @default.
- W1971970107 hasPublicationYear "1993" @default.
- W1971970107 type Work @default.
- W1971970107 sameAs 1971970107 @default.
- W1971970107 citedByCount "0" @default.
- W1971970107 crossrefType "proceedings-article" @default.
- W1971970107 hasAuthorship W1971970107A5003281170 @default.
- W1971970107 hasAuthorship W1971970107A5028187863 @default.
- W1971970107 hasAuthorship W1971970107A5036729951 @default.
- W1971970107 hasAuthorship W1971970107A5057583779 @default.
- W1971970107 hasAuthorship W1971970107A5081430818 @default.
- W1971970107 hasAuthorship W1971970107A5085135656 @default.
- W1971970107 hasAuthorship W1971970107A5089735473 @default.
- W1971970107 hasBestOaLocation W19719701072 @default.
- W1971970107 hasConcept C121332964 @default.
- W1971970107 hasConcept C38349280 @default.
- W1971970107 hasConcept C41008148 @default.
- W1971970107 hasConcept C57879066 @default.
- W1971970107 hasConceptScore W1971970107C121332964 @default.
- W1971970107 hasConceptScore W1971970107C38349280 @default.
- W1971970107 hasConceptScore W1971970107C41008148 @default.
- W1971970107 hasConceptScore W1971970107C57879066 @default.
- W1971970107 hasLocation W19719701071 @default.
- W1971970107 hasLocation W19719701072 @default.
- W1971970107 hasLocation W19719701073 @default.
- W1971970107 hasLocation W19719701074 @default.
- W1971970107 hasOpenAccess W1971970107 @default.
- W1971970107 hasPrimaryLocation W19719701071 @default.
- W1971970107 hasRelatedWork W2049775471 @default.
- W1971970107 hasRelatedWork W2093578348 @default.
- W1971970107 hasRelatedWork W2350741829 @default.
- W1971970107 hasRelatedWork W2358668433 @default.
- W1971970107 hasRelatedWork W2376932109 @default.
- W1971970107 hasRelatedWork W2382290278 @default.
- W1971970107 hasRelatedWork W2390279801 @default.
- W1971970107 hasRelatedWork W2748952813 @default.
- W1971970107 hasRelatedWork W2899084033 @default.
- W1971970107 hasRelatedWork W2530322880 @default.
- W1971970107 isParatext "false" @default.
- W1971970107 isRetracted "false" @default.
- W1971970107 magId "1971970107" @default.
- W1971970107 workType "article" @default.