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- W1971982009 abstract "Ocular pursuit in monkeys, elicited by sinusoidal and triangular (constant velocity) stimuli, was studied before and after lesions of the nucleus of the optic tract (NOT). Before NOT lesions, pursuit gains (eye velocity/target velocity) were close to unity for sinusoidal and constant-velocity stimuli at frequencies up to 1 Hz. In this range, retinal slip was less than 2 degrees. Electrode tracks made to identify the location of NOT caused deficits in ipsilateral pursuit, which later recovered. Small electrolytic lesions of NOT reduced ipsilateral pursuit gains to below 0.5 in all tested conditions. Pursuit was better, however, when the eyes moved from the contralateral side toward the center (centripetal pursuit) than from the center ipsilaterally (centrifugal pursuit), although the eyes remained in close proximity to the target with saccadic tracking. Effects of lesions on ipsilateral pursuit were not permanent, and pursuit gains had generally recovered to 60-80% of baseline after about 2 weeks. One animal had bilateral NOT lesions and lost pursuit for 4 days. Thereafter, it had a centrifugal pursuit deficit that lasted for more than 2 months. Vertical pursuit and visually guided saccades were not affected by the bilateral NOT lesions in this animal. We also compared effects of these and similar NOT lesions on optokinetic nystagmus (OKN) and optokinetic after-nystagmus (OKAN). Correlation of functional deficits with NOT lesions from this and previous studies showed that rostral lesions of NOT in and around the pretectal olivary nucleus, which interrupted cortical input through the brachium of the superior colliculus (BSC), affected both smooth pursuit and OKN. In two animals in which it was tested, NOT lesions that caused a deficit in pursuit also decreased the rapid and slow components of OKN slow-phase velocity and affected OKAN. It was previously shown that slightly more caudal NOT lesions were more effective in altering gain adaptation of the angular vestibulo-ocular reflex (aVOR). The present findings suggest that cortical pathways through rostral NOT play an important role in maintenance of ipsilateral ocular pursuit. Since lesions that affected ocular pursuit had similar effects on ipsilateral OKN, processing for these two functions is probably closely linked in NOT, as it is elsewhere." @default.
- W1971982009 created "2016-06-24" @default.
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- W1971982009 date "2000-04-01" @default.
- W1971982009 modified "2023-10-10" @default.
- W1971982009 title "Functions of the nucleus of the optic tract (NOT)." @default.
- W1971982009 cites W139909623 @default.
- W1971982009 cites W140561089 @default.
- W1971982009 cites W1521483404 @default.
- W1971982009 cites W1538520695 @default.
- W1971982009 cites W1545365849 @default.
- W1971982009 cites W1824438194 @default.
- W1971982009 cites W1837967720 @default.
- W1971982009 cites W1864451846 @default.
- W1971982009 cites W191720258 @default.
- W1971982009 cites W1928111876 @default.
- W1971982009 cites W1972246417 @default.
- W1971982009 cites W1972313558 @default.
- W1971982009 cites W1977870546 @default.
- W1971982009 cites W1977957137 @default.
- W1971982009 cites W1979551625 @default.
- W1971982009 cites W1980214769 @default.
- W1971982009 cites W1987111578 @default.
- W1971982009 cites W1988448904 @default.
- W1971982009 cites W1991939593 @default.
- W1971982009 cites W1993122472 @default.
- W1971982009 cites W1997479315 @default.
- W1971982009 cites W2000475039 @default.
- W1971982009 cites W2003257084 @default.
- W1971982009 cites W2007778340 @default.
- W1971982009 cites W2009181467 @default.
- W1971982009 cites W2009544912 @default.
- W1971982009 cites W2010027630 @default.
- W1971982009 cites W2014575636 @default.
- W1971982009 cites W2015596037 @default.
- W1971982009 cites W2027051557 @default.
- W1971982009 cites W2027979299 @default.
- W1971982009 cites W2031223264 @default.
- W1971982009 cites W2031938836 @default.
- W1971982009 cites W2036158022 @default.
- W1971982009 cites W2036243221 @default.
- W1971982009 cites W2039665163 @default.
- W1971982009 cites W2047480119 @default.
- W1971982009 cites W2050630474 @default.
- W1971982009 cites W2052353625 @default.
- W1971982009 cites W2055091435 @default.
- W1971982009 cites W2055655708 @default.
- W1971982009 cites W2057926731 @default.
- W1971982009 cites W2060104917 @default.
- W1971982009 cites W2062321064 @default.
- W1971982009 cites W2075746035 @default.
- W1971982009 cites W2078104185 @default.
- W1971982009 cites W2081258618 @default.
- W1971982009 cites W2083185192 @default.
- W1971982009 cites W2083786068 @default.
- W1971982009 cites W2084064234 @default.
- W1971982009 cites W2088014595 @default.
- W1971982009 cites W2088242371 @default.
- W1971982009 cites W2091096566 @default.
- W1971982009 cites W2132346173 @default.
- W1971982009 cites W2134395659 @default.
- W1971982009 cites W2140768179 @default.
- W1971982009 cites W2212801949 @default.
- W1971982009 cites W2276275738 @default.
- W1971982009 cites W2281020433 @default.
- W1971982009 cites W2331843993 @default.
- W1971982009 cites W2338788501 @default.
- W1971982009 cites W2405468734 @default.
- W1971982009 cites W2406470292 @default.
- W1971982009 cites W2406544371 @default.
- W1971982009 cites W2408102716 @default.
- W1971982009 cites W2410080439 @default.
- W1971982009 cites W2410302463 @default.
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- W1971982009 doi "https://doi.org/10.1007/s002219900302" @default.
- W1971982009 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2002478" @default.
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