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- W1972027457 abstract "Various aminoazo dyes were administered to rats and the amount of 4′-hydroxylated metabolites in the liver was estimated. For these dyes having an unsubstituted 4′-position the degree of 4′-hydroxylation did not correlate with their carcinogenic potency. On the other hand, 4′-substituted aminoazo dyes suffered replacement of the substituent by a hydroxyl group to an extent which was proportional to their carcinogenic activity. The results are interpreted as offering support for the proposal that the intermediate formation of arylhydroxylamines from aminoazo dyes has carcinogenic significance." @default.
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- W1972027457 date "1966-09-01" @default.
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- W1972027457 title "The hydroxylation and carcinogenicity in vivo of aminoazo dyes" @default.
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- W1972027457 doi "https://doi.org/10.1016/0006-2952(66)90050-5" @default.
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