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- W1972033559 abstract "SUMMARY Human mononuclcar leucocytes (MNL) or the adherent fraction (monocytes) produced tumour necrosis factor-alpha (TNF-α) (by EL1SA) in culture when stimulated with killed Staphylococcus aureus. The bisbenzylisoquinoline alkaloid, tetrandrine inhibited the capacity of MNL and monocytes to produce TNF-α at a concentration range of 0·1 to 5 μg/ml. Tetrandrine may be potentially useful in the treatment of inflammatory diseases in which TNF-α plays a major role." @default.
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- W1972033559 date "1990-05-01" @default.
- W1972033559 modified "2023-10-12" @default.
- W1972033559 title "Tetrandrine, a plant alkaloid, inhibits the production of tumour necrosis factor-alpha (cachectin) hy human monocytes" @default.
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- W1972033559 doi "https://doi.org/10.1111/j.1365-2249.1990.tb05239.x" @default.
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