FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972036562> ?p ?o ?g. }

• W1972036562 abstract "Identifying Plasmodium vivax antigen-specific antibodies associated with P. vivax infection and protective immunity is key to the development of serosurveillance tools and vaccines for malaria. Antibody targets of P. vivax can be identified by seroepidemiological studies of individuals living in P. vivax-endemic areas, and is an important strategy given the limited ability to culture P. vivax in vitro. There have been numerous studies investigating the association between P. vivax antibody responses and P. vivax infection, but there has been no standardization of results to enable comparisons across populations. We performed a systematic review with meta-analysis of population-based, cross-sectional, case-control, and cohort studies of individuals living in P. vivax-endemic areas. We searched 6 databases and identified 18 studies that met predefined inclusion and quality criteria, and examined the association between antibody responses to P. vivax antigens and P. vivax malaria. The majority of studies were published in South America (all from Brazil) and the rest from geographically diverse areas in the Asia-Pacific region. Considerable heterogeneity in estimates was observed, but IgG responses to PvCSP, PvMSP-119, PvMSP-9RIRII, and PvAMA1 were associated with increased odds of P. vivax infection in geographically diverse populations. Potential sources of heterogeneity included study design, different transmission intensities and transmigrant populations. Protective associations were observed for antibodies to PvMSP-119, PvMSP-1NT, PvMSP-3α and PvMSP-9NT antigens, but only in single geographical locations. This systematic review revealed several antigen-specific antibodies that were associated with active infection and protective immunity, which may be useful biomarkers. However, more studies are needed on additional antigens, particularly cohort studies to increase the body of evidence for protective immunity. More studies representing diverse geographical regions encompassing varying P. vivax endemicities are needed to validate the generalizability of the findings and to provide a solid evidence base for the use of P. vivax antigens in vaccines and serosurveillance tools." @default.
• W1972036562 created "2016-06-24" @default.
• W1972036562 creator A5007135659 @default.
• W1972036562 creator A5016683377 @default.
• W1972036562 creator A5050635434 @default.
• W1972036562 creator A5072563667 @default.
• W1972036562 creator A5077385105 @default.
• W1972036562 creator A5080489391 @default.
• W1972036562 date "2014-09-09" @default.
• W1972036562 modified "2023-10-06" @default.
• W1972036562 title "Immunological markers of Plasmodium vivaxexposure and immunity: a systematic review and meta-analysis" @default.
• W1972036562 cites W103823305 @default.
• W1972036562 cites W1527871699 @default.
• W1972036562 cites W1834650926 @default.
• W1972036562 cites W1839670086 @default.
• W1972036562 cites W1965267710 @default.
• W1972036562 cites W1966013767 @default.
• W1972036562 cites W1967015536 @default.
• W1972036562 cites W1971051257 @default.
• W1972036562 cites W1979423827 @default.
• W1972036562 cites W1984639393 @default.
• W1972036562 cites W1986159395 @default.
• W1972036562 cites W1992332433 @default.
• W1972036562 cites W1992816019 @default.
• W1972036562 cites W1994761559 @default.
• W1972036562 cites W1996494698 @default.
• W1972036562 cites W2000210592 @default.
• W1972036562 cites W2001707467 @default.
• W1972036562 cites W2005370556 @default.
• W1972036562 cites W2013287995 @default.
• W1972036562 cites W2016447317 @default.
• W1972036562 cites W2024734857 @default.
• W1972036562 cites W2025126181 @default.
• W1972036562 cites W2033761910 @default.
• W1972036562 cites W2036875255 @default.
• W1972036562 cites W2037964949 @default.
• W1972036562 cites W2050200376 @default.
• W1972036562 cites W2056140371 @default.
• W1972036562 cites W2056401826 @default.
• W1972036562 cites W2059439388 @default.
• W1972036562 cites W2062094955 @default.
• W1972036562 cites W2067620951 @default.
• W1972036562 cites W2073100171 @default.
• W1972036562 cites W2074905094 @default.
• W1972036562 cites W2082260480 @default.
• W1972036562 cites W2082400094 @default.
• W1972036562 cites W2089518061 @default.
• W1972036562 cites W2091899884 @default.
• W1972036562 cites W2092271748 @default.
• W1972036562 cites W2097432479 @default.
• W1972036562 cites W2099551104 @default.
• W1972036562 cites W2101246531 @default.
• W1972036562 cites W2102871981 @default.
• W1972036562 cites W2107328434 @default.
• W1972036562 cites W2107754088 @default.
• W1972036562 cites W2108476551 @default.
• W1972036562 cites W2112985118 @default.
• W1972036562 cites W2113442583 @default.
• W1972036562 cites W2119040598 @default.
• W1972036562 cites W2125435699 @default.
• W1972036562 cites W2126904900 @default.
• W1972036562 cites W2126930838 @default.
• W1972036562 cites W2132078046 @default.
• W1972036562 cites W2144112749 @default.
• W1972036562 cites W2146245884 @default.
• W1972036562 cites W2148310626 @default.
• W1972036562 cites W2152490244 @default.
• W1972036562 cites W2155612959 @default.
• W1972036562 cites W2156052556 @default.
• W1972036562 cites W2156921694 @default.
• W1972036562 cites W2157176215 @default.
• W1972036562 cites W2158823754 @default.
• W1972036562 cites W2159276995 @default.
• W1972036562 cites W2161601517 @default.
• W1972036562 cites W2163037807 @default.
• W1972036562 cites W2164192745 @default.
• W1972036562 cites W2168138163 @default.
• W1972036562 cites W2244674613 @default.
• W1972036562 cites W2411440147 @default.
• W1972036562 cites W2793593056 @default.
• W1972036562 cites W4294215472 @default.
• W1972036562 doi "https://doi.org/10.1186/s12916-014-0150-1" @default.
• W1972036562 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4172944" @default.
• W1972036562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25199532" @default.
• W1972036562 hasPublicationYear "2014" @default.
• W1972036562 type Work @default.
• W1972036562 sameAs 1972036562 @default.
• W1972036562 citedByCount "66" @default.
• W1972036562 countsByYear W19720365622015 @default.
• W1972036562 countsByYear W19720365622016 @default.
• W1972036562 countsByYear W19720365622017 @default.
• W1972036562 countsByYear W19720365622018 @default.
• W1972036562 countsByYear W19720365622019 @default.
• W1972036562 countsByYear W19720365622020 @default.
• W1972036562 countsByYear W19720365622021 @default.
• W1972036562 countsByYear W19720365622022 @default.
• W1972036562 countsByYear W19720365622023 @default.
• W1972036562 crossrefType "journal-article" @default.
• W1972036562 hasAuthorship W1972036562A5007135659 @default.
• W1972036562 hasAuthorship W1972036562A5016683377 @default.

• next