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- W1972110218 abstract "Caenorhabditis elegans (C.elegans) has great potential as a model organism because of its genetic homology with human. So various studies on human neural network in organism level have been studied with C.elegans. Furthermore, C.elegans respond clearly on a various stimuli including chemical gradient, temperature, electric field, light, and other chemical/physical stimuli. C. elegans live under the environment with complex combination of these stimuli but previous studies only have focused on the single stimulus conditions. Here, we developed a microfluidic system for analyzing the behavioral response of C.elegans to physical complex stimuli; temperature gradient and electric field. Also, we compared the responses of wild type (N2) and mutant worms (PR678, IK589, BC347, and CB78) with this device to show that the specific gene affects on the behavior of C. elegans. The developed device has a potential to be a tool for the behavior of C. elegans and to be applied for studying of human nerve system." @default.
- W1972110218 created "2016-06-24" @default.
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- W1972110218 date "2015-01-01" @default.
- W1972110218 modified "2023-09-29" @default.
- W1972110218 title "Behavior Response of Caenorhabditis Elegans to Physical Complex Stimuli in a Controlled Microfluidic System" @default.
- W1972110218 doi "https://doi.org/10.1016/j.bpj.2014.11.955" @default.
- W1972110218 hasPublicationYear "2015" @default.
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