FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972155449> ?p ?o ?g. }

• W1972155449 endingPage "59" @default.
• W1972155449 startingPage "53" @default.
• W1972155449 abstract "Pterodontic acid (PA) has been isolated from Laggera pterodonta, a Chinese herbal medicine, and shown to possess antibacterial activity in vitro. To facilitate its preclinical development, the interaction between PA and bovine serum albumin (BSA) was studied using a fluorescence quenching technique, ultraviolet–visible spectrophotometry and dynamic light scattering (DLS). At temperatures of 297 K and 310 K and an excitation wavelength of 282 nm, the fluorescence intensity of BSA decreased significantly with increasing concentration of PA attributed to the formation of a PA–BSA complex. The apparent binding constant, number of binding sites and corresponding thermodynamic parameters were calculated and the main intermolecular attraction shown to result from hydrogen bonding and van der Waals forces. Synchronous fluorescence spectrometry revealed that the binding site in the complex approached the microenvironment of Trp and three-dimensional fluorescence spectroscopy showed the binding induced conformational changes in BSA. Using DLS, increasing PA concentration was shown to cause a gradual increase in hydrodynamic diameter and significant aggregation of the complex." @default.
• W1972155449 created "2016-06-24" @default.
• W1972155449 creator A5005239588 @default.
• W1972155449 creator A5038633996 @default.
• W1972155449 creator A5071907234 @default.
• W1972155449 date "2012-02-01" @default.
• W1972155449 modified "2023-09-29" @default.
• W1972155449 title "Spectroscopic and dynamic light scattering studies of the interaction between pterodontic acid and bovine serum albumin" @default.
• W1972155449 cites W1504792186 @default.
• W1972155449 cites W1973238993 @default.
• W1972155449 cites W1978787427 @default.
• W1972155449 cites W1989339135 @default.
• W1972155449 cites W1991395401 @default.
• W1972155449 cites W1992768908 @default.
• W1972155449 cites W1994521301 @default.
• W1972155449 cites W1995556873 @default.
• W1972155449 cites W1996536752 @default.
• W1972155449 cites W2013089335 @default.
• W1972155449 cites W2014262451 @default.
• W1972155449 cites W2037128898 @default.
• W1972155449 cites W2039999116 @default.
• W1972155449 cites W2040184556 @default.
• W1972155449 cites W2044008108 @default.
• W1972155449 cites W2050639822 @default.
• W1972155449 cites W2065944438 @default.
• W1972155449 cites W2071834260 @default.
• W1972155449 cites W2075705506 @default.
• W1972155449 cites W2083142355 @default.
• W1972155449 cites W4238539670 @default.
• W1972155449 cites W87190817 @default.
• W1972155449 doi "https://doi.org/10.1016/j.apsb.2011.12.001" @default.
• W1972155449 hasPublicationYear "2012" @default.
• W1972155449 type Work @default.
• W1972155449 sameAs 1972155449 @default.
• W1972155449 citedByCount "47" @default.
• W1972155449 countsByYear W19721554492013 @default.
• W1972155449 countsByYear W19721554492014 @default.
• W1972155449 countsByYear W19721554492015 @default.
• W1972155449 countsByYear W19721554492016 @default.
• W1972155449 countsByYear W19721554492017 @default.
• W1972155449 countsByYear W19721554492018 @default.
• W1972155449 countsByYear W19721554492019 @default.
• W1972155449 countsByYear W19721554492020 @default.
• W1972155449 countsByYear W19721554492021 @default.
• W1972155449 countsByYear W19721554492022 @default.
• W1972155449 countsByYear W19721554492023 @default.
• W1972155449 crossrefType "journal-article" @default.
• W1972155449 hasAuthorship W1972155449A5005239588 @default.
• W1972155449 hasAuthorship W1972155449A5038633996 @default.
• W1972155449 hasAuthorship W1972155449A5071907234 @default.
• W1972155449 hasBestOaLocation W19721554491 @default.
• W1972155449 hasConcept C107824862 @default.
• W1972155449 hasConcept C112887158 @default.
• W1972155449 hasConcept C113196181 @default.
• W1972155449 hasConcept C121332964 @default.
• W1972155449 hasConcept C121745418 @default.
• W1972155449 hasConcept C126061179 @default.
• W1972155449 hasConcept C14631669 @default.
• W1972155449 hasConcept C155672457 @default.
• W1972155449 hasConcept C158711907 @default.
• W1972155449 hasConcept C165616093 @default.
• W1972155449 hasConcept C166950319 @default.
• W1972155449 hasConcept C171250308 @default.
• W1972155449 hasConcept C178790620 @default.
• W1972155449 hasConcept C185592680 @default.
• W1972155449 hasConcept C192562407 @default.
• W1972155449 hasConcept C32786932 @default.
• W1972155449 hasConcept C32909587 @default.
• W1972155449 hasConcept C43617362 @default.
• W1972155449 hasConcept C55493867 @default.
• W1972155449 hasConcept C62520636 @default.
• W1972155449 hasConcept C75473681 @default.
• W1972155449 hasConcept C8010536 @default.
• W1972155449 hasConcept C86807702 @default.
• W1972155449 hasConcept C90260826 @default.
• W1972155449 hasConcept C91881484 @default.
• W1972155449 hasConceptScore W1972155449C107824862 @default.
• W1972155449 hasConceptScore W1972155449C112887158 @default.
• W1972155449 hasConceptScore W1972155449C113196181 @default.
• W1972155449 hasConceptScore W1972155449C121332964 @default.
• W1972155449 hasConceptScore W1972155449C121745418 @default.
• W1972155449 hasConceptScore W1972155449C126061179 @default.
• W1972155449 hasConceptScore W1972155449C14631669 @default.
• W1972155449 hasConceptScore W1972155449C155672457 @default.
• W1972155449 hasConceptScore W1972155449C158711907 @default.
• W1972155449 hasConceptScore W1972155449C165616093 @default.
• W1972155449 hasConceptScore W1972155449C166950319 @default.
• W1972155449 hasConceptScore W1972155449C171250308 @default.
• W1972155449 hasConceptScore W1972155449C178790620 @default.
• W1972155449 hasConceptScore W1972155449C185592680 @default.
• W1972155449 hasConceptScore W1972155449C192562407 @default.
• W1972155449 hasConceptScore W1972155449C32786932 @default.
• W1972155449 hasConceptScore W1972155449C32909587 @default.
• W1972155449 hasConceptScore W1972155449C43617362 @default.
• W1972155449 hasConceptScore W1972155449C55493867 @default.
• W1972155449 hasConceptScore W1972155449C62520636 @default.
• W1972155449 hasConceptScore W1972155449C75473681 @default.
• W1972155449 hasConceptScore W1972155449C8010536 @default.

• next