FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972156987> ?p ?o ?g. }

• W1972156987 endingPage "749" @default.
• W1972156987 startingPage "733" @default.
• W1972156987 abstract "Several features of activation of mouse peritoneal macrophages were elicited by 1-2-d exposure to submicrogram concentrations of anti-Mac-1 (M1/70), a rat monoclonal antibody that reacts with the alpha chain of complement receptor type 3 (Mac-1). The changes induced included enhanced capacity to secrete H2O2 when triggered with PMA, decreased secretion of proteins, increased expression of Ia antigen and decreased phagocytosis of particles. These changes closely resembled those induced by rIFN-gamma in type, extent, and time course. The concentration of M1/70 IgG resulting in 50% of the maximal activation of macrophage H2O2-releasing capacity averaged 0.18 +/- 0.03 micrograms/ml. This activation was not blocked by anti-FcR mAb, and could be reproduced with M18/2, a mAb against beta chain of Mac-1, suggesting that a direct ligation of Mac-1 with mAb was responsible for the activation. Neither depletion of T cells nor addition of neutralizing Abs to IFN-gamma or TNF-alpha prevented M1/70-mediated macrophage activation. Moreover, F(ab')2 of M1/70, or plating of macrophages on C3bi-coated surfaces, inhibited the activation of macrophages by rIFN-gamma. These findings suggest that Mac-1 (CR3) may play an important role in macrophage activation." @default.
• W1972156987 created "2016-06-24" @default.
• W1972156987 creator A5000793262 @default.
• W1972156987 creator A5076210539 @default.
• W1972156987 creator A5077276012 @default.
• W1972156987 date "1987-03-01" @default.
• W1972156987 modified "2023-09-26" @default.
• W1972156987 title "Activation of mouse peritoneal macrophages by monoclonal antibodies to Mac-1 (complement receptor type 3)." @default.
• W1972156987 cites W1505010441 @default.
• W1972156987 cites W1505476215 @default.
• W1972156987 cites W1536018543 @default.
• W1972156987 cites W1544345395 @default.
• W1972156987 cites W1564309137 @default.
• W1972156987 cites W1588364673 @default.
• W1972156987 cites W1591899727 @default.
• W1972156987 cites W1599436637 @default.
• W1972156987 cites W1609249008 @default.
• W1972156987 cites W1668274701 @default.
• W1972156987 cites W1775749144 @default.
• W1972156987 cites W1825331915 @default.
• W1972156987 cites W1855820603 @default.
• W1972156987 cites W1976773412 @default.
• W1972156987 cites W1994805857 @default.
• W1972156987 cites W1997297528 @default.
• W1972156987 cites W2002475242 @default.
• W1972156987 cites W2005905661 @default.
• W1972156987 cites W2016450225 @default.
• W1972156987 cites W2017596457 @default.
• W1972156987 cites W2020089973 @default.
• W1972156987 cites W2023094887 @default.
• W1972156987 cites W2027562868 @default.
• W1972156987 cites W2027972898 @default.
• W1972156987 cites W2038398469 @default.
• W1972156987 cites W2039148627 @default.
• W1972156987 cites W2048325240 @default.
• W1972156987 cites W2055092075 @default.
• W1972156987 cites W2065871536 @default.
• W1972156987 cites W2071615710 @default.
• W1972156987 cites W2077702220 @default.
• W1972156987 cites W2080580789 @default.
• W1972156987 cites W2081070214 @default.
• W1972156987 cites W2083119829 @default.
• W1972156987 cites W2089967575 @default.
• W1972156987 cites W2091535618 @default.
• W1972156987 cites W2094151171 @default.
• W1972156987 cites W2104030642 @default.
• W1972156987 cites W2105074038 @default.
• W1972156987 cites W2116996002 @default.
• W1972156987 cites W2117206496 @default.
• W1972156987 cites W2117279773 @default.
• W1972156987 cites W2127061414 @default.
• W1972156987 cites W2141715517 @default.
• W1972156987 cites W2142812822 @default.
• W1972156987 cites W2144382102 @default.
• W1972156987 cites W2159069239 @default.
• W1972156987 cites W2164001459 @default.
• W1972156987 cites W2165835604 @default.
• W1972156987 cites W2171070360 @default.
• W1972156987 cites W2172982769 @default.
• W1972156987 cites W2218403526 @default.
• W1972156987 cites W2310464721 @default.
• W1972156987 cites W2340679956 @default.
• W1972156987 cites W2418470223 @default.
• W1972156987 cites W2463880119 @default.
• W1972156987 doi "https://doi.org/10.1084/jem.165.3.733" @default.
• W1972156987 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2188277" @default.
• W1972156987 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3102677" @default.
• W1972156987 hasPublicationYear "1987" @default.
• W1972156987 type Work @default.
• W1972156987 sameAs 1972156987 @default.
• W1972156987 citedByCount "61" @default.
• W1972156987 countsByYear W19721569872014 @default.
• W1972156987 countsByYear W19721569872017 @default.
• W1972156987 countsByYear W19721569872018 @default.
• W1972156987 countsByYear W19721569872020 @default.
• W1972156987 countsByYear W19721569872021 @default.
• W1972156987 countsByYear W19721569872022 @default.
• W1972156987 crossrefType "journal-article" @default.
• W1972156987 hasAuthorship W1972156987A5000793262 @default.
• W1972156987 hasAuthorship W1972156987A5076210539 @default.
• W1972156987 hasAuthorship W1972156987A5077276012 @default.
• W1972156987 hasBestOaLocation W19721569871 @default.
• W1972156987 hasConcept C111684460 @default.
• W1972156987 hasConcept C147483822 @default.
• W1972156987 hasConcept C153911025 @default.
• W1972156987 hasConcept C159654299 @default.
• W1972156987 hasConcept C160448771 @default.
• W1972156987 hasConcept C170493617 @default.
• W1972156987 hasConcept C175773311 @default.
• W1972156987 hasConcept C185592680 @default.
• W1972156987 hasConcept C202751555 @default.
• W1972156987 hasConcept C203014093 @default.
• W1972156987 hasConcept C2779244956 @default.
• W1972156987 hasConcept C2779931124 @default.
• W1972156987 hasConcept C49039625 @default.
• W1972156987 hasConcept C542903549 @default.
• W1972156987 hasConcept C55493867 @default.
• W1972156987 hasConcept C86803240 @default.

• next