FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972171082> ?p ?o ?g. }

• W1972171082 abstract "To determine the relationship among the DNA ploidy, histopathologic features, and clinical syndrome in adrenal cortical adenomas, because the cells often show variability in nuclear size and configuration.Our study included 44 adenomas associated with primary aldosteronism and 23 adenomas associated with Cushing syndrome. Normal adrenal glands from patients with renal carcinoma served as the controls. Paraffin-embedded tissues were examined for DNA content by flow cytometry. The mean percentage of G(2)/M (4C%) of the control samples was 3.8%. Tetraploid was represented by a histogram with both a 4C peak greater than 9% (mean + 2.4 SD of control samples) and a small 8C peak.Flow cytometric analysis revealed diploidy in 30, tetraploidy in 27, and aneuploidy in 8 of the 67 adenomas; 2 adenomas could not be classified. All 17 normal adrenal glands showed diploidy. A significant relationship was noted between DNA ploidy and the clinical syndrome (ie, a larger proportion of adenomas with primary aldosteronism had a tetraploid DNA histogram compared with adenomas with Cushing syndrome, P <0. 0001). Adenomas with primary aldosteronism had a significantly higher nuclear grade (III or IV) than did tumors with Cushing syndrome (P = 0.033). A significant relationship was also observed between DNA ploidy and nuclear grade in 57 euploid tumors, with tetraploid tumors often showing the highest nuclear grade (P = 0. 037).Our results have demonstrated that adrenal cortical adenomas associated with primary aldosteronism often reveal severe nuclear pleomorphism, indicating that nuclear pleomorphism might be due to a tetraploid stemline." @default.
• W1972171082 created "2016-06-24" @default.
• W1972171082 creator A5013724819 @default.
• W1972171082 creator A5043058133 @default.
• W1972171082 creator A5044112315 @default.
• W1972171082 creator A5046786824 @default.
• W1972171082 creator A5079627883 @default.
• W1972171082 creator A5088279051 @default.
• W1972171082 date "2000-08-01" @default.
• W1972171082 modified "2023-09-23" @default.
• W1972171082 title "Relationship between flow cytometric DNA ploidy and nuclear grade with endocrine dysfunction in adrenal cortical adenomas" @default.
• W1972171082 cites W102525666 @default.
• W1972171082 cites W152175249 @default.
• W1972171082 cites W1536690700 @default.
• W1972171082 cites W1972686052 @default.
• W1972171082 cites W1977783785 @default.
• W1972171082 cites W1988623266 @default.
• W1972171082 cites W1996659056 @default.
• W1972171082 cites W2018708063 @default.
• W1972171082 cites W2032587761 @default.
• W1972171082 cites W2039545078 @default.
• W1972171082 cites W2039836243 @default.
• W1972171082 cites W2072921325 @default.
• W1972171082 cites W2091317335 @default.
• W1972171082 cites W2091512576 @default.
• W1972171082 cites W2113103626 @default.
• W1972171082 cites W2315321516 @default.
• W1972171082 cites W2321504557 @default.
• W1972171082 cites W2414027368 @default.
• W1972171082 cites W2416355654 @default.
• W1972171082 cites W2426122711 @default.
• W1972171082 cites W2435909319 @default.
• W1972171082 cites W2479518716 @default.
• W1972171082 cites W573536579 @default.
• W1972171082 cites W64582691 @default.
• W1972171082 cites W2430595106 @default.
• W1972171082 doi "https://doi.org/10.1016/s0090-4295(00)00568-9" @default.
• W1972171082 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10925119" @default.
• W1972171082 hasPublicationYear "2000" @default.
• W1972171082 type Work @default.
• W1972171082 sameAs 1972171082 @default.
• W1972171082 citedByCount "5" @default.
• W1972171082 countsByYear W19721710822013 @default.
• W1972171082 countsByYear W19721710822015 @default.
• W1972171082 crossrefType "journal-article" @default.
• W1972171082 hasAuthorship W1972171082A5013724819 @default.
• W1972171082 hasAuthorship W1972171082A5043058133 @default.
• W1972171082 hasAuthorship W1972171082A5044112315 @default.
• W1972171082 hasAuthorship W1972171082A5046786824 @default.
• W1972171082 hasAuthorship W1972171082A5079627883 @default.
• W1972171082 hasAuthorship W1972171082A5088279051 @default.
• W1972171082 hasConcept C104317684 @default.
• W1972171082 hasConcept C115960442 @default.
• W1972171082 hasConcept C126322002 @default.
• W1972171082 hasConcept C142724271 @default.
• W1972171082 hasConcept C143191323 @default.
• W1972171082 hasConcept C24586158 @default.
• W1972171082 hasConcept C2777428134 @default.
• W1972171082 hasConcept C2778525890 @default.
• W1972171082 hasConcept C2779672484 @default.
• W1972171082 hasConcept C2780233176 @default.
• W1972171082 hasConcept C30481170 @default.
• W1972171082 hasConcept C55493867 @default.
• W1972171082 hasConcept C71924100 @default.
• W1972171082 hasConcept C86803240 @default.
• W1972171082 hasConceptScore W1972171082C104317684 @default.
• W1972171082 hasConceptScore W1972171082C115960442 @default.
• W1972171082 hasConceptScore W1972171082C126322002 @default.
• W1972171082 hasConceptScore W1972171082C142724271 @default.
• W1972171082 hasConceptScore W1972171082C143191323 @default.
• W1972171082 hasConceptScore W1972171082C24586158 @default.
• W1972171082 hasConceptScore W1972171082C2777428134 @default.
• W1972171082 hasConceptScore W1972171082C2778525890 @default.
• W1972171082 hasConceptScore W1972171082C2779672484 @default.
• W1972171082 hasConceptScore W1972171082C2780233176 @default.
• W1972171082 hasConceptScore W1972171082C30481170 @default.
• W1972171082 hasConceptScore W1972171082C55493867 @default.
• W1972171082 hasConceptScore W1972171082C71924100 @default.
• W1972171082 hasConceptScore W1972171082C86803240 @default.
• W1972171082 hasLocation W19721710821 @default.
• W1972171082 hasLocation W19721710822 @default.
• W1972171082 hasOpenAccess W1972171082 @default.
• W1972171082 hasPrimaryLocation W19721710821 @default.
• W1972171082 hasRelatedWork W135345367 @default.
• W1972171082 hasRelatedWork W1845348005 @default.
• W1972171082 hasRelatedWork W1987834893 @default.
• W1972171082 hasRelatedWork W1996659056 @default.
• W1972171082 hasRelatedWork W2008489856 @default.
• W1972171082 hasRelatedWork W2009022446 @default.
• W1972171082 hasRelatedWork W2037370980 @default.
• W1972171082 hasRelatedWork W2039764143 @default.
• W1972171082 hasRelatedWork W2045967515 @default.
• W1972171082 hasRelatedWork W2048532689 @default.
• W1972171082 hasRelatedWork W2050217402 @default.
• W1972171082 hasRelatedWork W2064583010 @default.
• W1972171082 hasRelatedWork W2082902019 @default.
• W1972171082 hasRelatedWork W2113103626 @default.
• W1972171082 hasRelatedWork W2320651327 @default.
• W1972171082 hasRelatedWork W2338914998 @default.
• W1972171082 hasRelatedWork W2409488274 @default.

• next