Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972195908> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W1972195908 abstract "To study the importance of the residual insulin secretion for the degree of diabetic control and for the development of microangiopathy 55 patients with non-insulin-dependent diabetes mellitus (NIDDM) were studied. A 1 hr oral glucose tolerance test was performed at diagnosis and 5-10 yr later. At diagnosis all patients were free of microangiopathy, at reassessment 24 patients had evidence of microangiopathy, i.e. retinopathy, neuropathy or nephropathy, alone or in combination. The glucose induced increments of insulin levels (delta IRI) at reassessment correlated inversely with the degree of diabetic control, measured by Haemoglobin A1 (r = -0.466, p less than 0.01), and with the mean fasting blood glucose throughout the follow up period (r = -0.491, p less than 0.01). delta IRI at diagnosis was similar in patients with and without microangiopathy, and at reassessment, although lower in the microangiopathy group (11.2 +/- 2.1 vs. 16.4 +/- 2.1 microunits/ml, p less than 0.1). The difference between the 2 groups did not reach statistical significance. When patients were separated into those treated with diet alone and those treated with oral antidiabetic agents, delta IRI at reassessment was significantly lower in patients on oral agents (10.5 +/- 1.9 vs. 17.2 +/- 2.2 microunits ml, p less than 0.01), but the prevalence of microangiopathy was not different between 2 groups (37% and 52%, respectively). These findings show that in patients with NIDDM the residual beta cell function is important for the degree of diabetic control, but a direct relationship between the degree of insulin deficiency and the presence of diabetic microangiopathy is not established." @default.
- W1972195908 created "2016-06-24" @default.
- W1972195908 creator A5006240624 @default.
- W1972195908 creator A5010525032 @default.
- W1972195908 creator A5071663333 @default.
- W1972195908 creator A5078428524 @default.
- W1972195908 date "1982-10-01" @default.
- W1972195908 modified "2023-10-16" @default.
- W1972195908 title "Insulin secretory response to oral glucose load, diabetic microangiopathy and diabetic control: A study in non-insulin dependent diabetics" @default.
- W1972195908 cites W1963676351 @default.
- W1972195908 cites W1966358947 @default.
- W1972195908 cites W1973114610 @default.
- W1972195908 cites W1973285756 @default.
- W1972195908 cites W1983586706 @default.
- W1972195908 cites W1989896488 @default.
- W1972195908 cites W2014271000 @default.
- W1972195908 cites W2029732561 @default.
- W1972195908 cites W2053863729 @default.
- W1972195908 cites W2056966934 @default.
- W1972195908 cites W2082912524 @default.
- W1972195908 cites W2083606604 @default.
- W1972195908 cites W2114541958 @default.
- W1972195908 cites W2132374778 @default.
- W1972195908 cites W2164252720 @default.
- W1972195908 cites W2169455254 @default.
- W1972195908 cites W2169558934 @default.
- W1972195908 cites W2313527545 @default.
- W1972195908 cites W2314684817 @default.
- W1972195908 cites W2314694370 @default.
- W1972195908 cites W2315326005 @default.
- W1972195908 cites W2321615924 @default.
- W1972195908 cites W2343306041 @default.
- W1972195908 cites W2401028121 @default.
- W1972195908 cites W2403905579 @default.
- W1972195908 cites W2414975866 @default.
- W1972195908 doi "https://doi.org/10.1016/0026-0495(82)90139-1" @default.
- W1972195908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6752636" @default.
- W1972195908 hasPublicationYear "1982" @default.
- W1972195908 type Work @default.
- W1972195908 sameAs 1972195908 @default.
- W1972195908 citedByCount "3" @default.
- W1972195908 countsByYear W19721959082016 @default.
- W1972195908 crossrefType "journal-article" @default.
- W1972195908 hasAuthorship W1972195908A5006240624 @default.
- W1972195908 hasAuthorship W1972195908A5010525032 @default.
- W1972195908 hasAuthorship W1972195908A5071663333 @default.
- W1972195908 hasAuthorship W1972195908A5078428524 @default.
- W1972195908 hasConcept C126322002 @default.
- W1972195908 hasConcept C134018914 @default.
- W1972195908 hasConcept C2776513394 @default.
- W1972195908 hasConcept C2778313320 @default.
- W1972195908 hasConcept C2779306644 @default.
- W1972195908 hasConcept C2779829184 @default.
- W1972195908 hasConcept C2779922275 @default.
- W1972195908 hasConcept C2781184683 @default.
- W1972195908 hasConcept C555293320 @default.
- W1972195908 hasConcept C70818257 @default.
- W1972195908 hasConcept C71924100 @default.
- W1972195908 hasConcept C90924648 @default.
- W1972195908 hasConceptScore W1972195908C126322002 @default.
- W1972195908 hasConceptScore W1972195908C134018914 @default.
- W1972195908 hasConceptScore W1972195908C2776513394 @default.
- W1972195908 hasConceptScore W1972195908C2778313320 @default.
- W1972195908 hasConceptScore W1972195908C2779306644 @default.
- W1972195908 hasConceptScore W1972195908C2779829184 @default.
- W1972195908 hasConceptScore W1972195908C2779922275 @default.
- W1972195908 hasConceptScore W1972195908C2781184683 @default.
- W1972195908 hasConceptScore W1972195908C555293320 @default.
- W1972195908 hasConceptScore W1972195908C70818257 @default.
- W1972195908 hasConceptScore W1972195908C71924100 @default.
- W1972195908 hasConceptScore W1972195908C90924648 @default.
- W1972195908 hasLocation W19721959081 @default.
- W1972195908 hasLocation W19721959082 @default.
- W1972195908 hasOpenAccess W1972195908 @default.
- W1972195908 hasPrimaryLocation W19721959081 @default.
- W1972195908 hasRelatedWork W132440217 @default.
- W1972195908 hasRelatedWork W1966780199 @default.
- W1972195908 hasRelatedWork W2024953843 @default.
- W1972195908 hasRelatedWork W2031292116 @default.
- W1972195908 hasRelatedWork W2072368805 @default.
- W1972195908 hasRelatedWork W2121704189 @default.
- W1972195908 hasRelatedWork W2162972075 @default.
- W1972195908 hasRelatedWork W2401111113 @default.
- W1972195908 hasRelatedWork W2424603456 @default.
- W1972195908 hasRelatedWork W2751573586 @default.
- W1972195908 isParatext "false" @default.
- W1972195908 isRetracted "false" @default.
- W1972195908 magId "1972195908" @default.
- W1972195908 workType "article" @default.