FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972247402> ?p ?o ?g. }

• W1972247402 endingPage "52" @default.
• W1972247402 startingPage "42" @default.
• W1972247402 abstract "Tobacco usage typically precedes illicit drug use in adolescent and young adult populations. Several animal studies suggest nicotine increases the risk for subsequent cocaine abuse, and may be a negative prognostic factor for treatment of cocaine addiction; i.e., a gateway drug. Neurotensin (NT) is a 13-amino acid neuropeptide that modulates dopamine, acetylcholine, glutamate, and GABA neurotransmission in brain reward pathways. NT69L, a NT(8-13) analog, blocks behavioral sensitization (an animal model for psychostimulant addiction) to nicotine, and nicotine self-administration in rats. The present study tested the effect of NT69L on the potentiating effects of nicotine on cocaine-induced locomotor sensitization. Male Wistar rats were injected daily for seven days with nicotine or saline (control) followed by four daily injections of cocaine. NT69L was administered 30 min prior to the last cocaine injection. Behavior was recorded with the use of activity chambers. Subchronic administration of nicotine enhanced cocaine-induced behavioral sensitization in Wistar rats, consistent with an hypothesized gateway effect. These behavioral effects of cocaine were attenuated by pretreatment with NT69L. The effect of the neurotensin agonist on cocaine sensitization in the nicotine treated group indicated a possible therapeutic effect for cocaine addiction, even in the presence of enhanced behavioral sensitization induced by nicotine." @default.
• W1972247402 created "2016-06-24" @default.
• W1972247402 creator A5002305452 @default.
• W1972247402 creator A5012485525 @default.
• W1972247402 creator A5022491022 @default.
• W1972247402 creator A5070646800 @default.
• W1972247402 date "2014-01-22" @default.
• W1972247402 modified "2023-10-16" @default.
• W1972247402 title "Neurotensin Agonist Attenuates Nicotine Potentiation to Cocaine Sensitization" @default.
• W1972247402 cites W1590331644 @default.
• W1972247402 cites W1820118415 @default.
• W1972247402 cites W1902584234 @default.
• W1972247402 cites W1963894788 @default.
• W1972247402 cites W1964953424 @default.
• W1972247402 cites W1971609010 @default.
• W1972247402 cites W1974207046 @default.
• W1972247402 cites W1981574077 @default.
• W1972247402 cites W1983869923 @default.
• W1972247402 cites W1984756007 @default.
• W1972247402 cites W1991608344 @default.
• W1972247402 cites W1994905576 @default.
• W1972247402 cites W2002859186 @default.
• W1972247402 cites W2007754730 @default.
• W1972247402 cites W2017614775 @default.
• W1972247402 cites W2022406556 @default.
• W1972247402 cites W2023670208 @default.
• W1972247402 cites W2027445806 @default.
• W1972247402 cites W2028424000 @default.
• W1972247402 cites W2030809600 @default.
• W1972247402 cites W2041092224 @default.
• W1972247402 cites W2050139121 @default.
• W1972247402 cites W2064419479 @default.
• W1972247402 cites W2075240784 @default.
• W1972247402 cites W2076456657 @default.
• W1972247402 cites W2078602453 @default.
• W1972247402 cites W2080074611 @default.
• W1972247402 cites W2081090190 @default.
• W1972247402 cites W2082958285 @default.
• W1972247402 cites W2084313998 @default.
• W1972247402 cites W2086911956 @default.
• W1972247402 cites W2091380181 @default.
• W1972247402 cites W2093716510 @default.
• W1972247402 cites W2102742834 @default.
• W1972247402 cites W2103610088 @default.
• W1972247402 cites W2105607151 @default.
• W1972247402 cites W2106459972 @default.
• W1972247402 cites W2106862702 @default.
• W1972247402 cites W2113753902 @default.
• W1972247402 cites W2123390413 @default.
• W1972247402 cites W2157372789 @default.
• W1972247402 cites W2167374867 @default.
• W1972247402 cites W2265262946 @default.
• W1972247402 cites W2289733791 @default.
• W1972247402 cites W4213265599 @default.
• W1972247402 doi "https://doi.org/10.3390/bs4010042" @default.
• W1972247402 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4219249" @default.
• W1972247402 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25379267" @default.
• W1972247402 hasPublicationYear "2014" @default.
• W1972247402 type Work @default.
• W1972247402 sameAs 1972247402 @default.
• W1972247402 citedByCount "4" @default.
• W1972247402 countsByYear W19722474022016 @default.
• W1972247402 countsByYear W19722474022017 @default.
• W1972247402 countsByYear W19722474022020 @default.
• W1972247402 crossrefType "journal-article" @default.
• W1972247402 hasAuthorship W1972247402A5002305452 @default.
• W1972247402 hasAuthorship W1972247402A5012485525 @default.
• W1972247402 hasAuthorship W1972247402A5022491022 @default.
• W1972247402 hasAuthorship W1972247402A5070646800 @default.
• W1972247402 hasBestOaLocation W19722474021 @default.
• W1972247402 hasConcept C118303440 @default.
• W1972247402 hasConcept C126322002 @default.
• W1972247402 hasConcept C134018914 @default.
• W1972247402 hasConcept C15744967 @default.
• W1972247402 hasConcept C169760540 @default.
• W1972247402 hasConcept C170493617 @default.
• W1972247402 hasConcept C185592680 @default.
• W1972247402 hasConcept C25274449 @default.
• W1972247402 hasConcept C2776217527 @default.
• W1972247402 hasConcept C2777667214 @default.
• W1972247402 hasConcept C2778938600 @default.
• W1972247402 hasConcept C2778976297 @default.
• W1972247402 hasConcept C2779547902 @default.
• W1972247402 hasConcept C48856860 @default.
• W1972247402 hasConcept C513476851 @default.
• W1972247402 hasConcept C71240020 @default.
• W1972247402 hasConcept C71924100 @default.
• W1972247402 hasConcept C98274493 @default.
• W1972247402 hasConceptScore W1972247402C118303440 @default.
• W1972247402 hasConceptScore W1972247402C126322002 @default.
• W1972247402 hasConceptScore W1972247402C134018914 @default.
• W1972247402 hasConceptScore W1972247402C15744967 @default.
• W1972247402 hasConceptScore W1972247402C169760540 @default.
• W1972247402 hasConceptScore W1972247402C170493617 @default.
• W1972247402 hasConceptScore W1972247402C185592680 @default.
• W1972247402 hasConceptScore W1972247402C25274449 @default.
• W1972247402 hasConceptScore W1972247402C2776217527 @default.
• W1972247402 hasConceptScore W1972247402C2777667214 @default.

• next