FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972269968> ?p ?o ?g. }

• W1972269968 endingPage "950" @default.
• W1972269968 startingPage "944" @default.
• W1972269968 abstract "Tenofovir disoproxil fumarate (tenofovir DF) is a bioavailable prodrug of tenofovir, a potent nucleotide analogue reverse-transcriptase inhibitor with activity against human immunodeficiency virus (HIV) and hepatitis B virus. It is administered as a single 300-mg tablet once daily. It was approved for the treatment of HIV infection on the basis of data from clinical trials demonstrating activity in treatment-experienced patients, and it was subsequently shown to be effective when used as a component of initial therapy. Tenofovir DF is active against some nucleoside-resistant strains of HIV. However, cross-resistance is associated with multiple thymidine analogue mutations that include 41L or 210W. The signature mutation is the K65R mutation, which causes variable loss in susceptibility to tenofovir DF, didanosine, and abacavir. Tenofovir DF has been well tolerated in clinical trials with durations of follow-up up to 96 weeks. It is associated with more-favorable lipid profiles than stavudine and has not been associated with the mitochondrial toxicity attributed to other nucleoside analogues." @default.
• W1972269968 created "2016-06-24" @default.
• W1972269968 creator A5048477426 @default.
• W1972269968 creator A5080503866 @default.
• W1972269968 date "2003-10-01" @default.
• W1972269968 modified "2023-09-27" @default.
• W1972269968 title "Tenofovir Disoproxil Fumarate" @default.
• W1972269968 cites W1979469335 @default.
• W1972269968 cites W1996313031 @default.
• W1972269968 cites W2042823706 @default.
• W1972269968 cites W2046348452 @default.
• W1972269968 cites W2111704741 @default.
• W1972269968 cites W2126327126 @default.
• W1972269968 cites W2130241957 @default.
• W1972269968 cites W2134575415 @default.
• W1972269968 cites W2142759829 @default.
• W1972269968 cites W2151425917 @default.
• W1972269968 cites W2161193921 @default.
• W1972269968 cites W2164903312 @default.
• W1972269968 cites W2313447461 @default.
• W1972269968 cites W2327827871 @default.
• W1972269968 doi "https://doi.org/10.1086/378068" @default.
• W1972269968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/13130407" @default.
• W1972269968 hasPublicationYear "2003" @default.
• W1972269968 type Work @default.
• W1972269968 sameAs 1972269968 @default.
• W1972269968 citedByCount "137" @default.
• W1972269968 countsByYear W19722699682012 @default.
• W1972269968 countsByYear W19722699682013 @default.
• W1972269968 countsByYear W19722699682014 @default.
• W1972269968 countsByYear W19722699682015 @default.
• W1972269968 countsByYear W19722699682016 @default.
• W1972269968 countsByYear W19722699682017 @default.
• W1972269968 countsByYear W19722699682018 @default.
• W1972269968 countsByYear W19722699682019 @default.
• W1972269968 countsByYear W19722699682020 @default.
• W1972269968 countsByYear W19722699682021 @default.
• W1972269968 countsByYear W19722699682022 @default.
• W1972269968 countsByYear W19722699682023 @default.
• W1972269968 crossrefType "journal-article" @default.
• W1972269968 hasAuthorship W1972269968A5048477426 @default.
• W1972269968 hasAuthorship W1972269968A5080503866 @default.
• W1972269968 hasBestOaLocation W19722699681 @default.
• W1972269968 hasConcept C104317684 @default.
• W1972269968 hasConcept C108215921 @default.
• W1972269968 hasConcept C156719811 @default.
• W1972269968 hasConcept C159047783 @default.
• W1972269968 hasConcept C2522874641 @default.
• W1972269968 hasConcept C2776452011 @default.
• W1972269968 hasConcept C2776543447 @default.
• W1972269968 hasConcept C2777071529 @default.
• W1972269968 hasConcept C2777333352 @default.
• W1972269968 hasConcept C2777351918 @default.
• W1972269968 hasConcept C2777447569 @default.
• W1972269968 hasConcept C2777869810 @default.
• W1972269968 hasConcept C2779344132 @default.
• W1972269968 hasConcept C2779465607 @default.
• W1972269968 hasConcept C2779889181 @default.
• W1972269968 hasConcept C2780593183 @default.
• W1972269968 hasConcept C2780727368 @default.
• W1972269968 hasConcept C3013748606 @default.
• W1972269968 hasConcept C55493867 @default.
• W1972269968 hasConcept C67705224 @default.
• W1972269968 hasConcept C71924100 @default.
• W1972269968 hasConcept C86803240 @default.
• W1972269968 hasConcept C98274493 @default.
• W1972269968 hasConceptScore W1972269968C104317684 @default.
• W1972269968 hasConceptScore W1972269968C108215921 @default.
• W1972269968 hasConceptScore W1972269968C156719811 @default.
• W1972269968 hasConceptScore W1972269968C159047783 @default.
• W1972269968 hasConceptScore W1972269968C2522874641 @default.
• W1972269968 hasConceptScore W1972269968C2776452011 @default.
• W1972269968 hasConceptScore W1972269968C2776543447 @default.
• W1972269968 hasConceptScore W1972269968C2777071529 @default.
• W1972269968 hasConceptScore W1972269968C2777333352 @default.
• W1972269968 hasConceptScore W1972269968C2777351918 @default.
• W1972269968 hasConceptScore W1972269968C2777447569 @default.
• W1972269968 hasConceptScore W1972269968C2777869810 @default.
• W1972269968 hasConceptScore W1972269968C2779344132 @default.
• W1972269968 hasConceptScore W1972269968C2779465607 @default.
• W1972269968 hasConceptScore W1972269968C2779889181 @default.
• W1972269968 hasConceptScore W1972269968C2780593183 @default.
• W1972269968 hasConceptScore W1972269968C2780727368 @default.
• W1972269968 hasConceptScore W1972269968C3013748606 @default.
• W1972269968 hasConceptScore W1972269968C55493867 @default.
• W1972269968 hasConceptScore W1972269968C67705224 @default.
• W1972269968 hasConceptScore W1972269968C71924100 @default.
• W1972269968 hasConceptScore W1972269968C86803240 @default.
• W1972269968 hasConceptScore W1972269968C98274493 @default.
• W1972269968 hasIssue "7" @default.
• W1972269968 hasLocation W19722699681 @default.
• W1972269968 hasLocation W19722699682 @default.
• W1972269968 hasOpenAccess W1972269968 @default.
• W1972269968 hasPrimaryLocation W19722699681 @default.
• W1972269968 hasRelatedWork W1972269968 @default.
• W1972269968 hasRelatedWork W1975492163 @default.
• W1972269968 hasRelatedWork W2001822825 @default.
• W1972269968 hasRelatedWork W2089353687 @default.

• next