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- W1972308081 abstract "A history of prolonged diphenylhydantoin (Dilantin) therapy was reported by 8 of 516 patients (1.6%) with Hodgkin's disease or non-Hodgkin's lymphoma, as compared with 3 of 516 patients (0.6%) with other cancers, and 2 of 516 (0.4%) tumor-free individuals. The findings, together with other published data, suggest a small excess risk of malignant lymphomas in patients receiving long-term treatment with this drug. The immunosuppressive effects of chronic diphenylhydantoin therapy may be involved in the pathogenesis of these neoplasms." @default.
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- W1972308081 date "1975-10-01" @default.
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- W1972308081 title "Malignant lymphoma after diphenylhydantoin (dilantin) therapy" @default.
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- W1972308081 doi "https://doi.org/10.1002/1097-0142(197510)36:4<1359::aid-cncr2820360426>3.0.co;2-l" @default.
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