Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972331292> ?p ?o ?g. }
- W1972331292 endingPage "23" @default.
- W1972331292 startingPage "18" @default.
- W1972331292 abstract "ObjectivesThe purpose of this study was to explore the clinical and laboratory characteristics of children with refractory Mycoplasma pneumoniae pneumonia (RMPP).MethodsSeventy-six children with RMPP and 26 children with non-refractory M. pneumoniae pneumonia (NRMPP), confirmed by both serology and fluorescent quantitation PCR in bronchoalveolar lavage fluid (BALF), were evaluated retrospectively.ResultsCompared to those with NRMPP, children with RMPP were older (66.6 ± 39.0 vs. 48.4 ± 35.4 months, p = 0.038) and had a longer duration of fever (12.7 ± 2.6 vs. 7.5 ± 1.8 days) and hospital stay (12.1 ± 3.2 vs. 7.4 ± 2.9 days). Children with RMPP presented neutrophil infiltration both in serum and BALF, as well as severe pulmonary lesions with pleural effusion. Children with RMPP had a significantly higher M. pneumoniae DNA load in BALF compared to NRMPP patients, and the M. pneumoniae load in BALF was significantly correlated with neutrophils and inversely correlated with macrophages for both the NRMPP and RMPP groups. The serum concentrations of tumor necrosis factor alpha (median 114.5 pg/ml, range 49.1–897.9 pg/ml) and interferon gamma (median 376.9 pg/ml, range 221.4–1997.6 pg/ml) were significantly higher in children with RMPP compared to children with NRMPP.ConclusionsThis study indicates that a direct microbe effect and the subsequent induced excessive host immune response contribute in part to the progression of RMPP." @default.
- W1972331292 created "2016-06-24" @default.
- W1972331292 creator A5019495050 @default.
- W1972331292 creator A5022227891 @default.
- W1972331292 creator A5041692641 @default.
- W1972331292 creator A5051186597 @default.
- W1972331292 creator A5062319901 @default.
- W1972331292 creator A5062324262 @default.
- W1972331292 creator A5075994044 @default.
- W1972331292 creator A5080546495 @default.
- W1972331292 creator A5081347616 @default.
- W1972331292 creator A5088089023 @default.
- W1972331292 creator A5090655358 @default.
- W1972331292 date "2014-12-01" @default.
- W1972331292 modified "2023-10-16" @default.
- W1972331292 title "Clinical and laboratory profiles of refractory Mycoplasma pneumoniae pneumonia in children" @default.
- W1972331292 cites W1898153797 @default.
- W1972331292 cites W1966788140 @default.
- W1972331292 cites W1975774707 @default.
- W1972331292 cites W1976869651 @default.
- W1972331292 cites W1981474601 @default.
- W1972331292 cites W1985593540 @default.
- W1972331292 cites W1988428393 @default.
- W1972331292 cites W2005490754 @default.
- W1972331292 cites W2008534031 @default.
- W1972331292 cites W2025686381 @default.
- W1972331292 cites W2039460302 @default.
- W1972331292 cites W2042870216 @default.
- W1972331292 cites W2066161072 @default.
- W1972331292 cites W206754304 @default.
- W1972331292 cites W2070360754 @default.
- W1972331292 cites W2082847086 @default.
- W1972331292 cites W2091419814 @default.
- W1972331292 cites W2097386432 @default.
- W1972331292 cites W2097625763 @default.
- W1972331292 cites W2098561255 @default.
- W1972331292 cites W2100004085 @default.
- W1972331292 cites W2110677468 @default.
- W1972331292 cites W2114786387 @default.
- W1972331292 cites W2116177799 @default.
- W1972331292 cites W2116961142 @default.
- W1972331292 cites W2117224202 @default.
- W1972331292 cites W2122216329 @default.
- W1972331292 cites W2122794983 @default.
- W1972331292 cites W2136167339 @default.
- W1972331292 cites W2142659422 @default.
- W1972331292 cites W2146154762 @default.
- W1972331292 cites W2146204188 @default.
- W1972331292 cites W2164001835 @default.
- W1972331292 cites W2167191971 @default.
- W1972331292 doi "https://doi.org/10.1016/j.ijid.2014.07.020" @default.
- W1972331292 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25449230" @default.
- W1972331292 hasPublicationYear "2014" @default.
- W1972331292 type Work @default.
- W1972331292 sameAs 1972331292 @default.
- W1972331292 citedByCount "80" @default.
- W1972331292 countsByYear W19723312922016 @default.
- W1972331292 countsByYear W19723312922017 @default.
- W1972331292 countsByYear W19723312922018 @default.
- W1972331292 countsByYear W19723312922019 @default.
- W1972331292 countsByYear W19723312922020 @default.
- W1972331292 countsByYear W19723312922021 @default.
- W1972331292 countsByYear W19723312922022 @default.
- W1972331292 countsByYear W19723312922023 @default.
- W1972331292 crossrefType "journal-article" @default.
- W1972331292 hasAuthorship W1972331292A5019495050 @default.
- W1972331292 hasAuthorship W1972331292A5022227891 @default.
- W1972331292 hasAuthorship W1972331292A5041692641 @default.
- W1972331292 hasAuthorship W1972331292A5051186597 @default.
- W1972331292 hasAuthorship W1972331292A5062319901 @default.
- W1972331292 hasAuthorship W1972331292A5062324262 @default.
- W1972331292 hasAuthorship W1972331292A5075994044 @default.
- W1972331292 hasAuthorship W1972331292A5080546495 @default.
- W1972331292 hasAuthorship W1972331292A5081347616 @default.
- W1972331292 hasAuthorship W1972331292A5088089023 @default.
- W1972331292 hasAuthorship W1972331292A5090655358 @default.
- W1972331292 hasBestOaLocation W19723312921 @default.
- W1972331292 hasConcept C126322002 @default.
- W1972331292 hasConcept C142424586 @default.
- W1972331292 hasConcept C159654299 @default.
- W1972331292 hasConcept C203014093 @default.
- W1972331292 hasConcept C2777714996 @default.
- W1972331292 hasConcept C2777914695 @default.
- W1972331292 hasConcept C2777961210 @default.
- W1972331292 hasConcept C2779215961 @default.
- W1972331292 hasConcept C2779634585 @default.
- W1972331292 hasConcept C45189115 @default.
- W1972331292 hasConcept C71924100 @default.
- W1972331292 hasConcept C86803240 @default.
- W1972331292 hasConcept C87355193 @default.
- W1972331292 hasConcept C90924648 @default.
- W1972331292 hasConceptScore W1972331292C126322002 @default.
- W1972331292 hasConceptScore W1972331292C142424586 @default.
- W1972331292 hasConceptScore W1972331292C159654299 @default.
- W1972331292 hasConceptScore W1972331292C203014093 @default.
- W1972331292 hasConceptScore W1972331292C2777714996 @default.
- W1972331292 hasConceptScore W1972331292C2777914695 @default.
- W1972331292 hasConceptScore W1972331292C2777961210 @default.