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- W1972345262 abstract "A carbapenem-resistant clinical isolate of Escherichia coli, which lacked OmpF and OmpC porins, carried a marR mutation and expressed a functional yedS, a normally nontranslated gene. MarR and YedS are described here as having effects on the ability of this strain to resist carbapenems. Additionally, expression of YedS was regulated by the small RNA MicF in a MarA-dependent way. These findings illustrate how broadly bacteria can mutate within a selective clinical setting, in this case, resistance to carbapenems, by altering three porin genes and one regulatory gene." @default.
- W1972345262 created "2016-06-24" @default.
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- W1972345262 date "2013-04-01" @default.
- W1972345262 modified "2023-10-15" @default.
- W1972345262 title "Involvement of MarR and YedS in Carbapenem Resistance in a Clinical Isolate of Escherichia coli from China" @default.
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- W1972345262 doi "https://doi.org/10.1128/aac.02445-12" @default.
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