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- W1972371713 abstract "Antibacterial activities of novel organoarsenic compounds As(III)-containing Schiff bases on Escherichia coli (CCTCCAB91112) were investigated by microcalorimetry in this study. The experimental result showed that the arsenic(III)-containing Schiff bases at micromolar concentration exhibit strong inhibition on the E. coli. Specifically, the growth rate constant k decreased, and the generation time t G and the inhibitory ratio I (percentage) increased with the increased dose of the arsenicals as inhibitors. All of the arsenicals display the feature of considerable lag phase inhibition on the cell growth. The compound 4-(4-bromobenzaliminyl)phenylarsenoxide makes the lag phase of E. coli cell growth cycles to reach 650 min at 5 μmol/L. The compounds with donating electron groups at aromatic ring B have lower IC50 to present higher antibacterial activity. The compound 4-(4-hydroxyl-3-methoxylbenzaliminyl)phenylarsenoxide has the lowest IC50 (1.82 μmol/L) to show the strongest antibacterial activity among them." @default.
- W1972371713 created "2016-06-24" @default.
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- W1972371713 date "2013-04-20" @default.
- W1972371713 modified "2023-09-27" @default.
- W1972371713 title "Antibacterial Evaluation of Novel Organoarsenic Compounds by the Microcalorimetric Method" @default.
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- W1972371713 doi "https://doi.org/10.1007/s12011-013-9660-5" @default.
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