Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972376577> ?p ?o ?g. }
- W1972376577 endingPage "151" @default.
- W1972376577 startingPage "141" @default.
- W1972376577 abstract "HIV-1 infection is often complicated by the dysfunction of central nervous system (CNS). Degenerative neuronal changes as well as neuronal loss have been documented in individuals with acquired immunodeficiency syndrome. Feline immunodeficiency virus (FIV) causes similar CNS manifestation and FIV infected cats provide an animal model for human immunodeficiency virus infection in humans. In this study, we examined the brain of FIV-infected cats and controls with immunohistochemical techniques using antibodies to microtubule-associated protein 2 (MAP-2) and glutamic acid decarboxylase (GAD). We found a significant decrease in expression of MAP-2 and GAD in neurons of infected animals compared to controls. In contrast, the expression of neurofilaments and glial fibrillary acidic protein was rather increased. The changes observed in the brain were similar to those seen in humans undergoing the normal aging process as well as those suffering from neurological diseases like Alzheimer's disease and other dementing disorders. These changes in the feline brain give insight into the deleterious effects of FIV on the CNS." @default.
- W1972376577 created "2016-06-24" @default.
- W1972376577 creator A5007167124 @default.
- W1972376577 creator A5009665821 @default.
- W1972376577 creator A5040549961 @default.
- W1972376577 creator A5048301116 @default.
- W1972376577 creator A5062976099 @default.
- W1972376577 creator A5087818472 @default.
- W1972376577 date "2001-01-01" @default.
- W1972376577 modified "2023-09-26" @default.
- W1972376577 title "Decreased Expression of MAP-2 and GAD in the Brain of Cats Infected with Feline Immunodeficiency Virus." @default.
- W1972376577 cites W144457579 @default.
- W1972376577 cites W1525259648 @default.
- W1972376577 cites W1593508376 @default.
- W1972376577 cites W1614954929 @default.
- W1972376577 cites W1970832843 @default.
- W1972376577 cites W1974165467 @default.
- W1972376577 cites W1975878673 @default.
- W1972376577 cites W1978460268 @default.
- W1972376577 cites W1983507869 @default.
- W1972376577 cites W1989483418 @default.
- W1972376577 cites W1991743392 @default.
- W1972376577 cites W1991840006 @default.
- W1972376577 cites W2003313975 @default.
- W1972376577 cites W2004403066 @default.
- W1972376577 cites W2005760793 @default.
- W1972376577 cites W2008339325 @default.
- W1972376577 cites W2010145371 @default.
- W1972376577 cites W2018135585 @default.
- W1972376577 cites W2021492630 @default.
- W1972376577 cites W2023206952 @default.
- W1972376577 cites W2034754449 @default.
- W1972376577 cites W2037183676 @default.
- W1972376577 cites W2044088430 @default.
- W1972376577 cites W2044590601 @default.
- W1972376577 cites W2047126558 @default.
- W1972376577 cites W2052487038 @default.
- W1972376577 cites W2054266998 @default.
- W1972376577 cites W2068477037 @default.
- W1972376577 cites W2068875641 @default.
- W1972376577 cites W2070841721 @default.
- W1972376577 cites W2071341341 @default.
- W1972376577 cites W2072480165 @default.
- W1972376577 cites W2073680886 @default.
- W1972376577 cites W2082361721 @default.
- W1972376577 cites W2086500520 @default.
- W1972376577 cites W2088087006 @default.
- W1972376577 cites W2090588483 @default.
- W1972376577 cites W2093681749 @default.
- W1972376577 cites W2096918711 @default.
- W1972376577 cites W2115584408 @default.
- W1972376577 cites W2130379332 @default.
- W1972376577 cites W2143637094 @default.
- W1972376577 cites W2152611825 @default.
- W1972376577 cites W2214984711 @default.
- W1972376577 cites W2415936841 @default.
- W1972376577 cites W4317563449 @default.
- W1972376577 doi "https://doi.org/10.1620/tjem.195.141" @default.
- W1972376577 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11874247" @default.
- W1972376577 hasPublicationYear "2001" @default.
- W1972376577 type Work @default.
- W1972376577 sameAs 1972376577 @default.
- W1972376577 citedByCount "7" @default.
- W1972376577 countsByYear W19723765772014 @default.
- W1972376577 countsByYear W19723765772017 @default.
- W1972376577 countsByYear W19723765772020 @default.
- W1972376577 countsByYear W19723765772021 @default.
- W1972376577 countsByYear W19723765772023 @default.
- W1972376577 crossrefType "journal-article" @default.
- W1972376577 hasAuthorship W1972376577A5007167124 @default.
- W1972376577 hasAuthorship W1972376577A5009665821 @default.
- W1972376577 hasAuthorship W1972376577A5040549961 @default.
- W1972376577 hasAuthorship W1972376577A5048301116 @default.
- W1972376577 hasAuthorship W1972376577A5062976099 @default.
- W1972376577 hasAuthorship W1972376577A5087818472 @default.
- W1972376577 hasBestOaLocation W19723765771 @default.
- W1972376577 hasConcept C126322002 @default.
- W1972376577 hasConcept C142724271 @default.
- W1972376577 hasConcept C157207234 @default.
- W1972376577 hasConcept C159047783 @default.
- W1972376577 hasConcept C159654299 @default.
- W1972376577 hasConcept C169760540 @default.
- W1972376577 hasConcept C181199279 @default.
- W1972376577 hasConcept C203014093 @default.
- W1972376577 hasConcept C204232928 @default.
- W1972376577 hasConcept C2522874641 @default.
- W1972376577 hasConcept C2776040883 @default.
- W1972376577 hasConcept C2777607303 @default.
- W1972376577 hasConcept C2777841672 @default.
- W1972376577 hasConcept C2779690655 @default.
- W1972376577 hasConcept C2779904517 @default.
- W1972376577 hasConcept C2780495277 @default.
- W1972376577 hasConcept C2780727368 @default.
- W1972376577 hasConcept C529278444 @default.
- W1972376577 hasConcept C55493867 @default.
- W1972376577 hasConcept C71924100 @default.
- W1972376577 hasConcept C86803240 @default.
- W1972376577 hasConcept C8891405 @default.