FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972376589> ?p ?o ?g. }

• W1972376589 endingPage "239" @default.
• W1972376589 startingPage "228" @default.
• W1972376589 abstract "Eukaryotic cells respond to cellular stresses by the inhibition of translation and the accumulation of mRNAs in cytoplasmic RNA-protein (ribonucleoprotein) granules termed stress granules and P-bodies. An unresolved issue is how different stresses affect formation of messenger RNP (mRNP) granules. In the present study, we examine how sodium azide (NaN(3)), which inhibits mitochondrial respiration, affects formation of mRNP granules as compared with glucose deprivation in budding yeast. We observed that NaN(3) treatment inhibits translation and triggers formation of P-bodies and stress granules. The composition of stress granules induced by NaN(3) differs from that of glucose-deprived cells by containing eukaryotic initiation factor (eIF)3, eIF4A/B, eIF5B and eIF1A proteins, and by lacking the heterogeneous nuclear RNP (hnRNP) protein Hrp1. Moreover, in contrast with glucose-deprived stress granules, NaN(3)-triggered stress granules show different assembly rules, form faster and independently from P-bodies and dock or merge with P-bodies over time. Strikingly, addition of NaN(3) and glucose deprivation in combination, regardless of the order, always results in stress granules of a glucose deprivation nature, suggesting that both granules share an mRNP remodeling pathway. These results indicate that stress granule assembly, kinetics and composition in yeast can vary in a stress-specific manner, which we suggest reflects different rate-limiting steps in a common mRNP remodeling pathway." @default.
• W1972376589 created "2016-06-24" @default.
• W1972376589 creator A5013145287 @default.
• W1972376589 creator A5014796446 @default.
• W1972376589 creator A5021452315 @default.
• W1972376589 date "2011-01-15" @default.
• W1972376589 modified "2023-10-05" @default.
• W1972376589 title "Stress-specific composition, assembly and kinetics of stress granules in <i>Saccharomyces cerevisiae</i>" @default.
• W1972376589 cites W1562248446 @default.
• W1972376589 cites W1964628768 @default.
• W1972376589 cites W1965424624 @default.
• W1972376589 cites W1968727721 @default.
• W1972376589 cites W1977809239 @default.
• W1972376589 cites W1992725525 @default.
• W1972376589 cites W1994186363 @default.
• W1972376589 cites W2003911773 @default.
• W1972376589 cites W2014241716 @default.
• W1972376589 cites W2031215995 @default.
• W1972376589 cites W2037313242 @default.
• W1972376589 cites W2038049104 @default.
• W1972376589 cites W2044821390 @default.
• W1972376589 cites W2062351682 @default.
• W1972376589 cites W2076495609 @default.
• W1972376589 cites W2077829198 @default.
• W1972376589 cites W2084119410 @default.
• W1972376589 cites W2093367919 @default.
• W1972376589 cites W2100277907 @default.
• W1972376589 cites W2101765148 @default.
• W1972376589 cites W2102953537 @default.
• W1972376589 cites W2108185386 @default.
• W1972376589 cites W2114717251 @default.
• W1972376589 cites W2116592258 @default.
• W1972376589 cites W2120156360 @default.
• W1972376589 cites W2120434672 @default.
• W1972376589 cites W2130349346 @default.
• W1972376589 cites W2134530067 @default.
• W1972376589 cites W2139297731 @default.
• W1972376589 cites W2141195616 @default.
• W1972376589 cites W2141325721 @default.
• W1972376589 cites W2143069387 @default.
• W1972376589 cites W2146865209 @default.
• W1972376589 cites W2148892576 @default.
• W1972376589 cites W2152758802 @default.
• W1972376589 cites W3006925957 @default.
• W1972376589 cites W4235035553 @default.
• W1972376589 doi "https://doi.org/10.1242/jcs.078444" @default.
• W1972376589 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3010191" @default.
• W1972376589 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21172806" @default.
• W1972376589 hasPublicationYear "2011" @default.
• W1972376589 type Work @default.
• W1972376589 sameAs 1972376589 @default.
• W1972376589 citedByCount "209" @default.
• W1972376589 countsByYear W19723765892012 @default.
• W1972376589 countsByYear W19723765892013 @default.
• W1972376589 countsByYear W19723765892014 @default.
• W1972376589 countsByYear W19723765892015 @default.
• W1972376589 countsByYear W19723765892016 @default.
• W1972376589 countsByYear W19723765892017 @default.
• W1972376589 countsByYear W19723765892018 @default.
• W1972376589 countsByYear W19723765892019 @default.
• W1972376589 countsByYear W19723765892020 @default.
• W1972376589 countsByYear W19723765892021 @default.
• W1972376589 countsByYear W19723765892022 @default.
• W1972376589 countsByYear W19723765892023 @default.
• W1972376589 crossrefType "journal-article" @default.
• W1972376589 hasAuthorship W1972376589A5013145287 @default.
• W1972376589 hasAuthorship W1972376589A5014796446 @default.
• W1972376589 hasAuthorship W1972376589A5021452315 @default.
• W1972376589 hasBestOaLocation W19723765891 @default.
• W1972376589 hasConcept C104317684 @default.
• W1972376589 hasConcept C105580179 @default.
• W1972376589 hasConcept C117838200 @default.
• W1972376589 hasConcept C128943096 @default.
• W1972376589 hasConcept C149364088 @default.
• W1972376589 hasConcept C151730666 @default.
• W1972376589 hasConcept C162419368 @default.
• W1972376589 hasConcept C2777576037 @default.
• W1972376589 hasConcept C2779222958 @default.
• W1972376589 hasConcept C2781452922 @default.
• W1972376589 hasConcept C3675279 @default.
• W1972376589 hasConcept C49760210 @default.
• W1972376589 hasConcept C55493867 @default.
• W1972376589 hasConcept C67705224 @default.
• W1972376589 hasConcept C75934600 @default.
• W1972376589 hasConcept C86803240 @default.
• W1972376589 hasConcept C95444343 @default.
• W1972376589 hasConceptScore W1972376589C104317684 @default.
• W1972376589 hasConceptScore W1972376589C105580179 @default.
• W1972376589 hasConceptScore W1972376589C117838200 @default.
• W1972376589 hasConceptScore W1972376589C128943096 @default.
• W1972376589 hasConceptScore W1972376589C149364088 @default.
• W1972376589 hasConceptScore W1972376589C151730666 @default.
• W1972376589 hasConceptScore W1972376589C162419368 @default.
• W1972376589 hasConceptScore W1972376589C2777576037 @default.
• W1972376589 hasConceptScore W1972376589C2779222958 @default.
• W1972376589 hasConceptScore W1972376589C2781452922 @default.
• W1972376589 hasConceptScore W1972376589C3675279 @default.
• W1972376589 hasConceptScore W1972376589C49760210 @default.

• next