Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972415545> ?p ?o ?g. }
- W1972415545 endingPage "279" @default.
- W1972415545 startingPage "270" @default.
- W1972415545 abstract "Tuberculosis (TB) remains a worldwide leading cause of death among infectious diseases. Development of safer and more efficacious vaccines requires a basic understanding of the protective mechanisms induced by BCG. Here we show that vaccination of cattle with BCG induces CD8+γ/δTCR−CD45RO+ T-cells that can produce IFN-γ, up-regulate transcription and expression of perforin, lyse BCG-infected monocyte-derived macrophages (MoMϕ) and contribute to a reduction in the number of intracellular mycobacteria. We also observed BCG-induced CD8+ responses in vivo. After infection of cattle with Mycobacterium bovis, CD8+γ/δTCR−CD45RO+ cells responded more strongly to M. bovis-infected MoMϕ than to BCG-infected MoMϕ. These results indicate that the antigen-specific CD8+ memory response resides in the CD8+γ/δTCR−CD45RO+ cell population." @default.
- W1972415545 created "2016-06-24" @default.
- W1972415545 creator A5005866571 @default.
- W1972415545 creator A5013672310 @default.
- W1972415545 creator A5034779320 @default.
- W1972415545 creator A5040650124 @default.
- W1972415545 creator A5042202065 @default.
- W1972415545 date "2009-01-01" @default.
- W1972415545 modified "2023-09-23" @default.
- W1972415545 title "The antigen-specific memory CD8+ T-cell response induced by BCG in cattle resides in the CD8+γ/δTCR−CD45RO+ T-cell population" @default.
- W1972415545 cites W1593220041 @default.
- W1972415545 cites W1877277475 @default.
- W1972415545 cites W1910115396 @default.
- W1972415545 cites W1915893748 @default.
- W1972415545 cites W1920701053 @default.
- W1972415545 cites W1965167105 @default.
- W1972415545 cites W1967203548 @default.
- W1972415545 cites W1967317248 @default.
- W1972415545 cites W1982727887 @default.
- W1972415545 cites W1989010022 @default.
- W1972415545 cites W1995096720 @default.
- W1972415545 cites W2000472705 @default.
- W1972415545 cites W2010353184 @default.
- W1972415545 cites W2016336432 @default.
- W1972415545 cites W2019205907 @default.
- W1972415545 cites W2021547823 @default.
- W1972415545 cites W2029697389 @default.
- W1972415545 cites W2035288424 @default.
- W1972415545 cites W2036218860 @default.
- W1972415545 cites W2036239318 @default.
- W1972415545 cites W2036474409 @default.
- W1972415545 cites W2045018004 @default.
- W1972415545 cites W2045188968 @default.
- W1972415545 cites W2047125790 @default.
- W1972415545 cites W2052791500 @default.
- W1972415545 cites W2055545187 @default.
- W1972415545 cites W2061142299 @default.
- W1972415545 cites W2063696360 @default.
- W1972415545 cites W2065992198 @default.
- W1972415545 cites W2066973840 @default.
- W1972415545 cites W2070241696 @default.
- W1972415545 cites W2070762058 @default.
- W1972415545 cites W2075773580 @default.
- W1972415545 cites W2084934744 @default.
- W1972415545 cites W2085197314 @default.
- W1972415545 cites W2093943879 @default.
- W1972415545 cites W2120249254 @default.
- W1972415545 cites W2127062586 @default.
- W1972415545 cites W2130873748 @default.
- W1972415545 cites W2134582553 @default.
- W1972415545 cites W2140202337 @default.
- W1972415545 cites W2141118380 @default.
- W1972415545 cites W2149349606 @default.
- W1972415545 cites W2150034287 @default.
- W1972415545 cites W2157559696 @default.
- W1972415545 cites W2157656284 @default.
- W1972415545 cites W2158035277 @default.
- W1972415545 cites W2159815477 @default.
- W1972415545 cites W2168466885 @default.
- W1972415545 cites W2208968527 @default.
- W1972415545 cites W2326027979 @default.
- W1972415545 cites W4253747742 @default.
- W1972415545 doi "https://doi.org/10.1016/j.vaccine.2008.10.053" @default.
- W1972415545 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18996428" @default.
- W1972415545 hasPublicationYear "2009" @default.
- W1972415545 type Work @default.
- W1972415545 sameAs 1972415545 @default.
- W1972415545 citedByCount "27" @default.
- W1972415545 countsByYear W19724155452012 @default.
- W1972415545 countsByYear W19724155452013 @default.
- W1972415545 countsByYear W19724155452014 @default.
- W1972415545 countsByYear W19724155452015 @default.
- W1972415545 countsByYear W19724155452017 @default.
- W1972415545 countsByYear W19724155452018 @default.
- W1972415545 countsByYear W19724155452019 @default.
- W1972415545 countsByYear W19724155452020 @default.
- W1972415545 countsByYear W19724155452021 @default.
- W1972415545 countsByYear W19724155452022 @default.
- W1972415545 crossrefType "journal-article" @default.
- W1972415545 hasAuthorship W1972415545A5005866571 @default.
- W1972415545 hasAuthorship W1972415545A5013672310 @default.
- W1972415545 hasAuthorship W1972415545A5034779320 @default.
- W1972415545 hasAuthorship W1972415545A5040650124 @default.
- W1972415545 hasAuthorship W1972415545A5042202065 @default.
- W1972415545 hasConcept C142724271 @default.
- W1972415545 hasConcept C147483822 @default.
- W1972415545 hasConcept C154317977 @default.
- W1972415545 hasConcept C159047783 @default.
- W1972415545 hasConcept C167672396 @default.
- W1972415545 hasConcept C19317047 @default.
- W1972415545 hasConcept C202751555 @default.
- W1972415545 hasConcept C203014093 @default.
- W1972415545 hasConcept C2776090121 @default.
- W1972415545 hasConcept C2777975735 @default.
- W1972415545 hasConcept C2778497218 @default.
- W1972415545 hasConcept C2781069245 @default.
- W1972415545 hasConcept C2908647359 @default.
- W1972415545 hasConcept C55493867 @default.