Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972425498> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W1972425498 endingPage "458" @default.
- W1972425498 startingPage "454" @default.
- W1972425498 abstract "Proton nuclear magnetic resonance (NMR) titration shifts are a very sensitive indication of proton dissociation from carboxyl groups and of hydrogen-bond formation between carboxylate groups and backbone amide protons. As a model protein, we selected bromelain inhibitor VI (BI-VI), which is a unique double-chain molecule (M r = 5888), and characterized almost all the proton resonances in the pH range of 1.5-9.9 by two-dimensional NMR. In this study, we first examined the ionization effects of Asp13H(β-CO2H) and Glu24H(γ-CO 2H) (superscript letters H and L indicate heavy and light chains, respectively). It was found that their ionization affected the chemical shifts of the surrounding protons through a maximum of seven consecutive covalent bonds, but scarcely through non-covalent bonds. Furthermore, it was revealed that the formation of two hydrogen bonds of Ser4L(NH)-Asp9H(β-CO 2H) and Lys19H(NH)-Asp32H(β-CO2H) influenced not only the chemical shifts of the amide protons of Ser4L and Lys19H but also those of the alpha protons of Asp9H and Asp32H. (Communicated by Masanori OTSUKA, M.J.A.)" @default.
- W1972425498 created "2016-06-24" @default.
- W1972425498 creator A5039444335 @default.
- W1972425498 creator A5049920381 @default.
- W1972425498 creator A5055220053 @default.
- W1972425498 date "2005-01-01" @default.
- W1972425498 modified "2023-10-16" @default.
- W1972425498 title "Effects of ionization on chemical shifts of the surrounding protons of bromelain inhibitor VI" @default.
- W1972425498 cites W1969564472 @default.
- W1972425498 cites W2000986554 @default.
- W1972425498 cites W2002484456 @default.
- W1972425498 cites W2020351375 @default.
- W1972425498 cites W2021534482 @default.
- W1972425498 cites W2029217032 @default.
- W1972425498 cites W2030901966 @default.
- W1972425498 cites W2032222792 @default.
- W1972425498 cites W2040351161 @default.
- W1972425498 cites W2082040139 @default.
- W1972425498 cites W2083179397 @default.
- W1972425498 doi "https://doi.org/10.2183/pjab.81.454" @default.
- W1972425498 hasPublicationYear "2005" @default.
- W1972425498 type Work @default.
- W1972425498 sameAs 1972425498 @default.
- W1972425498 citedByCount "0" @default.
- W1972425498 crossrefType "journal-article" @default.
- W1972425498 hasAuthorship W1972425498A5039444335 @default.
- W1972425498 hasAuthorship W1972425498A5049920381 @default.
- W1972425498 hasAuthorship W1972425498A5055220053 @default.
- W1972425498 hasBestOaLocation W19724254981 @default.
- W1972425498 hasConcept C102931765 @default.
- W1972425498 hasConcept C103319777 @default.
- W1972425498 hasConcept C111429119 @default.
- W1972425498 hasConcept C112887158 @default.
- W1972425498 hasConcept C121332964 @default.
- W1972425498 hasConcept C145148216 @default.
- W1972425498 hasConcept C147789679 @default.
- W1972425498 hasConcept C178790620 @default.
- W1972425498 hasConcept C180577832 @default.
- W1972425498 hasConcept C184866935 @default.
- W1972425498 hasConcept C185592680 @default.
- W1972425498 hasConcept C198291218 @default.
- W1972425498 hasConcept C2778074193 @default.
- W1972425498 hasConcept C2778439535 @default.
- W1972425498 hasConcept C32909587 @default.
- W1972425498 hasConcept C54516573 @default.
- W1972425498 hasConcept C62520636 @default.
- W1972425498 hasConcept C71240020 @default.
- W1972425498 hasConcept C8010536 @default.
- W1972425498 hasConceptScore W1972425498C102931765 @default.
- W1972425498 hasConceptScore W1972425498C103319777 @default.
- W1972425498 hasConceptScore W1972425498C111429119 @default.
- W1972425498 hasConceptScore W1972425498C112887158 @default.
- W1972425498 hasConceptScore W1972425498C121332964 @default.
- W1972425498 hasConceptScore W1972425498C145148216 @default.
- W1972425498 hasConceptScore W1972425498C147789679 @default.
- W1972425498 hasConceptScore W1972425498C178790620 @default.
- W1972425498 hasConceptScore W1972425498C180577832 @default.
- W1972425498 hasConceptScore W1972425498C184866935 @default.
- W1972425498 hasConceptScore W1972425498C185592680 @default.
- W1972425498 hasConceptScore W1972425498C198291218 @default.
- W1972425498 hasConceptScore W1972425498C2778074193 @default.
- W1972425498 hasConceptScore W1972425498C2778439535 @default.
- W1972425498 hasConceptScore W1972425498C32909587 @default.
- W1972425498 hasConceptScore W1972425498C54516573 @default.
- W1972425498 hasConceptScore W1972425498C62520636 @default.
- W1972425498 hasConceptScore W1972425498C71240020 @default.
- W1972425498 hasConceptScore W1972425498C8010536 @default.
- W1972425498 hasIssue "10" @default.
- W1972425498 hasLocation W19724254981 @default.
- W1972425498 hasOpenAccess W1972425498 @default.
- W1972425498 hasPrimaryLocation W19724254981 @default.
- W1972425498 hasRelatedWork W107688216 @default.
- W1972425498 hasRelatedWork W1607344735 @default.
- W1972425498 hasRelatedWork W1986913362 @default.
- W1972425498 hasRelatedWork W1993197092 @default.
- W1972425498 hasRelatedWork W2047487329 @default.
- W1972425498 hasRelatedWork W2398492406 @default.
- W1972425498 hasRelatedWork W2463632264 @default.
- W1972425498 hasRelatedWork W2509864854 @default.
- W1972425498 hasRelatedWork W2797259985 @default.
- W1972425498 hasRelatedWork W3094816455 @default.
- W1972425498 hasVolume "81" @default.
- W1972425498 isParatext "false" @default.
- W1972425498 isRetracted "false" @default.
- W1972425498 magId "1972425498" @default.
- W1972425498 workType "article" @default.