Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972451806> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W1972451806 abstract "Purpose: To investigate the variations in bone volume calculations in mice involved in aging research when changing cone beam micro-CT x-ray and reconstruction parameters. Methods: Mouse spines were placed on an indexed turn table that rotated 0.5° per projection and imaged by a self-built micro CT machine containing a CCD-based high-resolution x-ray detector. After the full 360° rotation data set of object images was obtained, a standard filtered back-projection cone beam reconstruction was performed. Four different kVp's between 40–70 kVp in 10kVp increments were selected. For each kVp two mAs settings were used. Each acquisition was reconstructed using two voxel sizes (12 and 25μm) and two step angles, 0.5° and 1°, respectively. A LabView program was written to determine the total bone volume contained in the mouse's total spine volume (bone plus gaps) as a measure of spine health. First, the user selected the desired 512×512 reconstruction to view the whole spine volume which was then used to select a gray-level threshold that allowed for viewing of the bone structure, then another threshold to include gaps. The program returned bone volume, bone × gap volume, and their ratio, BVF. Results: The calculated bone volume fractions were compared as a functionmore » of tube potential. Cases with 25μm slice thickness showed trials with lower kVp's had greater image contrast, which resulted in higher calculated bone volume fractions. Cases with 12μm reconstructed slice thickness were significantly noisier, and showed no clear maximum BVF. Conclusion: Using the projection images and reconstructions acquired from the micro CT, it can be shown that the micro-CT x-ray and reconstruction parameters significantly affect the total bone volume calculations. When comparing mice cohorts treated with different therapies researchers need to be aware of such details and use volumes which were acquired and processed in identical conditions.« less" @default.
- W1972451806 created "2016-06-24" @default.
- W1972451806 creator A5011614552 @default.
- W1972451806 creator A5014822894 @default.
- W1972451806 creator A5071814775 @default.
- W1972451806 creator A5075363370 @default.
- W1972451806 creator A5088541982 @default.
- W1972451806 date "2014-05-29" @default.
- W1972451806 modified "2023-09-27" @default.
- W1972451806 title "SU-E-T-143: Effect of X-Ray and Cone Beam CT Reconstruction Parameters On Estimation of Bone Volume of Mice Used in Aging Research" @default.
- W1972451806 doi "https://doi.org/10.1118/1.4888473" @default.
- W1972451806 hasPublicationYear "2014" @default.
- W1972451806 type Work @default.
- W1972451806 sameAs 1972451806 @default.
- W1972451806 citedByCount "0" @default.
- W1972451806 crossrefType "journal-article" @default.
- W1972451806 hasAuthorship W1972451806A5011614552 @default.
- W1972451806 hasAuthorship W1972451806A5014822894 @default.
- W1972451806 hasAuthorship W1972451806A5071814775 @default.
- W1972451806 hasAuthorship W1972451806A5075363370 @default.
- W1972451806 hasAuthorship W1972451806A5088541982 @default.
- W1972451806 hasConcept C11413529 @default.
- W1972451806 hasConcept C120665830 @default.
- W1972451806 hasConcept C121332964 @default.
- W1972451806 hasConcept C126838900 @default.
- W1972451806 hasConcept C136229726 @default.
- W1972451806 hasConcept C141379421 @default.
- W1972451806 hasConcept C163716698 @default.
- W1972451806 hasConcept C192562407 @default.
- W1972451806 hasConcept C20556612 @default.
- W1972451806 hasConcept C2779813781 @default.
- W1972451806 hasConcept C2989005 @default.
- W1972451806 hasConcept C33923547 @default.
- W1972451806 hasConcept C54170458 @default.
- W1972451806 hasConcept C544519230 @default.
- W1972451806 hasConcept C57493831 @default.
- W1972451806 hasConcept C62520636 @default.
- W1972451806 hasConcept C71924100 @default.
- W1972451806 hasConceptScore W1972451806C11413529 @default.
- W1972451806 hasConceptScore W1972451806C120665830 @default.
- W1972451806 hasConceptScore W1972451806C121332964 @default.
- W1972451806 hasConceptScore W1972451806C126838900 @default.
- W1972451806 hasConceptScore W1972451806C136229726 @default.
- W1972451806 hasConceptScore W1972451806C141379421 @default.
- W1972451806 hasConceptScore W1972451806C163716698 @default.
- W1972451806 hasConceptScore W1972451806C192562407 @default.
- W1972451806 hasConceptScore W1972451806C20556612 @default.
- W1972451806 hasConceptScore W1972451806C2779813781 @default.
- W1972451806 hasConceptScore W1972451806C2989005 @default.
- W1972451806 hasConceptScore W1972451806C33923547 @default.
- W1972451806 hasConceptScore W1972451806C54170458 @default.
- W1972451806 hasConceptScore W1972451806C544519230 @default.
- W1972451806 hasConceptScore W1972451806C57493831 @default.
- W1972451806 hasConceptScore W1972451806C62520636 @default.
- W1972451806 hasConceptScore W1972451806C71924100 @default.
- W1972451806 hasLocation W19724518061 @default.
- W1972451806 hasOpenAccess W1972451806 @default.
- W1972451806 hasPrimaryLocation W19724518061 @default.
- W1972451806 hasRelatedWork W1586985454 @default.
- W1972451806 hasRelatedWork W1909162429 @default.
- W1972451806 hasRelatedWork W1965461273 @default.
- W1972451806 hasRelatedWork W1969900083 @default.
- W1972451806 hasRelatedWork W1977590277 @default.
- W1972451806 hasRelatedWork W1987035613 @default.
- W1972451806 hasRelatedWork W1995256602 @default.
- W1972451806 hasRelatedWork W1999577837 @default.
- W1972451806 hasRelatedWork W2000277753 @default.
- W1972451806 hasRelatedWork W2142288207 @default.
- W1972451806 hasRelatedWork W2166708571 @default.
- W1972451806 hasRelatedWork W2372812474 @default.
- W1972451806 hasRelatedWork W2466299396 @default.
- W1972451806 hasRelatedWork W2476119202 @default.
- W1972451806 hasRelatedWork W2511283247 @default.
- W1972451806 hasRelatedWork W2521108168 @default.
- W1972451806 hasRelatedWork W2554782258 @default.
- W1972451806 hasRelatedWork W2620602984 @default.
- W1972451806 hasRelatedWork W3030574564 @default.
- W1972451806 hasRelatedWork W3206889331 @default.
- W1972451806 isParatext "false" @default.
- W1972451806 isRetracted "false" @default.
- W1972451806 magId "1972451806" @default.
- W1972451806 workType "article" @default.