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- W1972487125 abstract "Abstract Purpose To compare the effectiveness and reproducibility of a new black‐blood sequence vs. a conventional bright‐blood gradient‐echo T2* sequence for myocardial iron overload measurement in thalassemia. Materials and Methods Twenty thalassemia patients were studied. Black‐blood sequence images were acquired in diastole after a double inversion recovery (DIR) preparation pulse. Bright‐blood sequence images were acquired in both early systole and late diastole. The data were randomized and the T2* analysis was performed blindly by two independent observers. Results The T2* values from the black‐blood sequence were comparable to those of the conventional bright‐blood sequence (25.7 ± 12.9 msec vs. 26.4 ± 14.2 msec in early systole, P = 0.44; and 25.2 ± 13.1 msec in late diastole, P = 0.41). The coefficient of variation (CV) for black‐blood image T2* analysis was 4.1% compared with 8.9% (early systole P = 0.03) and 7.8% (late diastole P = 0.05) for bright‐blood image analysis. Conclusion The black‐blood T2* technique yields high‐contrast myocardial images, provides clearly depicted myocardial borders, and avoids blood signal contamination of the myocardium while yielding improvements in interobserver variability. J. Magn. Reson. Imaging 2007;25:1205–1209. © 2007 Wiley‐Liss, Inc." @default.
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- W1972487125 date "2007-05-22" @default.
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- W1972487125 title "Black-blood T2* technique for myocardial iron measurement in thalassemia" @default.
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- W1972487125 doi "https://doi.org/10.1002/jmri.20929" @default.
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