Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972502981> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1972502981 abstract "Purpose: With the increasing use of conformal radiation therapy methods for lungcancer, it is a necessity to accurately determine respiratory induced tumor motion. The purpose of this study is to analyze the motion characteristics of early stage lungtumors in a large population, and correlate tumor motion with position and other clinical factors. Method and Materials: 113 patients with 119 early stage non‐small cell lungtumors were analyzed. Each patient received a 4DCT scan. To determine tumor motion, a soft‐tissue based rigid registration algorithm was used to track the tumor position in ten respiratory phases. Tumor positions were standardized to correlate with their motion characteristics and other clinical factors, which included the lobe location, TMN staging information and etc. Diaphragm motion was calculated by subtracting the diaphragm position between the expiration and the inspiration phase. Tumor volumes were determined based on the GTV drawn by physicians on the expiration phase. Results: Average tumor motion in the AP, SI, and RL directions were 3.1±2.2mm, 6.3±6mm, and 1.5±1.4mm respectively. Lower lobe tumors showed an average vector motion (±1SD) of 11.6±7mm while upper/mid lobe tumors only averaged 5.3±4mm. To fully cover 95% of the tumors, a margin of 6.8mm, 18.3mm, and 3.9mm was needed in the AP, SI, and RL directions. From two‐tailed Spearman's rho correlations, tumor SI motion was strongly correlated with AP and SI positions of the tumor in the thorax, with correlation coefficients of −0.418 and 0.584 respectively. Diaphragm motion and tumor volume were not correlated with tumor motion. Conclusion: Respiratory induced lungtumor motion is primarily in the SI direction. Tumors in the lower lobe on average double the motion range of upper/mid tumors. Because the magnitude of tumor motion is different in each direction, it is beneficial to use an asymmetrical CTV margin for radiotherapy planning." @default.
- W1972502981 created "2016-06-24" @default.
- W1972502981 creator A5010762574 @default.
- W1972502981 creator A5025660683 @default.
- W1972502981 creator A5041943880 @default.
- W1972502981 creator A5044401242 @default.
- W1972502981 creator A5051391435 @default.
- W1972502981 creator A5057641050 @default.
- W1972502981 creator A5058839299 @default.
- W1972502981 creator A5079524412 @default.
- W1972502981 creator A5088144406 @default.
- W1972502981 date "2008-06-01" @default.
- W1972502981 modified "2023-09-25" @default.
- W1972502981 title "SU-GG-J-132: Motion Characterization for Early Stage Non-Small Cell Lung Cancer" @default.
- W1972502981 doi "https://doi.org/10.1118/1.2961681" @default.
- W1972502981 hasPublicationYear "2008" @default.
- W1972502981 type Work @default.
- W1972502981 sameAs 1972502981 @default.
- W1972502981 citedByCount "0" @default.
- W1972502981 crossrefType "journal-article" @default.
- W1972502981 hasAuthorship W1972502981A5010762574 @default.
- W1972502981 hasAuthorship W1972502981A5025660683 @default.
- W1972502981 hasAuthorship W1972502981A5041943880 @default.
- W1972502981 hasAuthorship W1972502981A5044401242 @default.
- W1972502981 hasAuthorship W1972502981A5051391435 @default.
- W1972502981 hasAuthorship W1972502981A5057641050 @default.
- W1972502981 hasAuthorship W1972502981A5058839299 @default.
- W1972502981 hasAuthorship W1972502981A5079524412 @default.
- W1972502981 hasAuthorship W1972502981A5088144406 @default.
- W1972502981 hasConcept C104114177 @default.
- W1972502981 hasConcept C121332964 @default.
- W1972502981 hasConcept C126322002 @default.
- W1972502981 hasConcept C126838900 @default.
- W1972502981 hasConcept C142724271 @default.
- W1972502981 hasConcept C146357865 @default.
- W1972502981 hasConcept C151730666 @default.
- W1972502981 hasConcept C157138929 @default.
- W1972502981 hasConcept C164292776 @default.
- W1972502981 hasConcept C24890656 @default.
- W1972502981 hasConcept C2776164194 @default.
- W1972502981 hasConcept C2776256026 @default.
- W1972502981 hasConcept C2908647359 @default.
- W1972502981 hasConcept C2989005 @default.
- W1972502981 hasConcept C509974204 @default.
- W1972502981 hasConcept C534529494 @default.
- W1972502981 hasConcept C71924100 @default.
- W1972502981 hasConcept C74650414 @default.
- W1972502981 hasConcept C86803240 @default.
- W1972502981 hasConcept C99454951 @default.
- W1972502981 hasConceptScore W1972502981C104114177 @default.
- W1972502981 hasConceptScore W1972502981C121332964 @default.
- W1972502981 hasConceptScore W1972502981C126322002 @default.
- W1972502981 hasConceptScore W1972502981C126838900 @default.
- W1972502981 hasConceptScore W1972502981C142724271 @default.
- W1972502981 hasConceptScore W1972502981C146357865 @default.
- W1972502981 hasConceptScore W1972502981C151730666 @default.
- W1972502981 hasConceptScore W1972502981C157138929 @default.
- W1972502981 hasConceptScore W1972502981C164292776 @default.
- W1972502981 hasConceptScore W1972502981C24890656 @default.
- W1972502981 hasConceptScore W1972502981C2776164194 @default.
- W1972502981 hasConceptScore W1972502981C2776256026 @default.
- W1972502981 hasConceptScore W1972502981C2908647359 @default.
- W1972502981 hasConceptScore W1972502981C2989005 @default.
- W1972502981 hasConceptScore W1972502981C509974204 @default.
- W1972502981 hasConceptScore W1972502981C534529494 @default.
- W1972502981 hasConceptScore W1972502981C71924100 @default.
- W1972502981 hasConceptScore W1972502981C74650414 @default.
- W1972502981 hasConceptScore W1972502981C86803240 @default.
- W1972502981 hasConceptScore W1972502981C99454951 @default.
- W1972502981 hasLocation W19725029811 @default.
- W1972502981 hasOpenAccess W1972502981 @default.
- W1972502981 hasPrimaryLocation W19725029811 @default.
- W1972502981 hasRelatedWork W1472930157 @default.
- W1972502981 hasRelatedWork W1538712324 @default.
- W1972502981 hasRelatedWork W1970053171 @default.
- W1972502981 hasRelatedWork W1983427194 @default.
- W1972502981 hasRelatedWork W1992406409 @default.
- W1972502981 hasRelatedWork W2003994065 @default.
- W1972502981 hasRelatedWork W2006114609 @default.
- W1972502981 hasRelatedWork W2006818915 @default.
- W1972502981 hasRelatedWork W2040291884 @default.
- W1972502981 hasRelatedWork W2042261159 @default.
- W1972502981 hasRelatedWork W2053071059 @default.
- W1972502981 hasRelatedWork W2058185386 @default.
- W1972502981 hasRelatedWork W2085976270 @default.
- W1972502981 hasRelatedWork W2089209044 @default.
- W1972502981 hasRelatedWork W2483108985 @default.
- W1972502981 hasRelatedWork W2552681962 @default.
- W1972502981 hasRelatedWork W2789725284 @default.
- W1972502981 hasRelatedWork W2993929872 @default.
- W1972502981 hasRelatedWork W3041533135 @default.
- W1972502981 hasRelatedWork W3203874075 @default.
- W1972502981 isParatext "false" @default.
- W1972502981 isRetracted "false" @default.
- W1972502981 magId "1972502981" @default.
- W1972502981 workType "article" @default.