Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972505501> ?p ?o ?g. }
- W1972505501 endingPage "543" @default.
- W1972505501 startingPage "535" @default.
- W1972505501 abstract "This experiment investigated the influence of age on prefrontal acetylcholine (ACh) release and Fos response in the hypothalamic paraventricular nucleus and the nucleus tractus solitarius (NTS) of rats following isoflurane anesthesia. It is known that isoflurane decreases acetylcholine release in most brain regions. In the present study, we found that the level of prefrontal acetylcholine was significantly lower in 28-month-old rats (14% of baseline) than in 3-month-old rats (38% of baseline) during 2 h of isoflurane anesthesia (P < 0.05). The old rat group showed significantly greater Fos induction in the paraventricular nucleus compared to the young adult rat group (P < 0.05), indicating that the old rats were subjected to stress. No difference in Fos response was noted in the nucleus tractus solitarius. The old rats displayed a significant increase in feeding behavior during the 3-h recovery period (P < 0.05), but there was no difference in overall acetylcholine levels. Taken together, these findings suggest that isoflurane anesthesia influences old rats more profoundly than young adult rats with regard to reductions in acetylcholine release and stress responses. This may have implications for understanding the development of postoperative delirium in aged patients." @default.
- W1972505501 created "2016-06-24" @default.
- W1972505501 creator A5020981755 @default.
- W1972505501 creator A5051342938 @default.
- W1972505501 creator A5063173227 @default.
- W1972505501 creator A5071998693 @default.
- W1972505501 creator A5077560958 @default.
- W1972505501 creator A5082356752 @default.
- W1972505501 creator A5086473480 @default.
- W1972505501 date "2004-12-01" @default.
- W1972505501 modified "2023-10-14" @default.
- W1972505501 title "Effects of isoflurane on prefrontal acetylcholine release and hypothalamic Fos response in young adult and aged rats" @default.
- W1972505501 cites W1529067373 @default.
- W1972505501 cites W1971524231 @default.
- W1972505501 cites W1971959365 @default.
- W1972505501 cites W1973548253 @default.
- W1972505501 cites W1983485985 @default.
- W1972505501 cites W1985754062 @default.
- W1972505501 cites W198865633 @default.
- W1972505501 cites W1990010166 @default.
- W1972505501 cites W1994301293 @default.
- W1972505501 cites W1996150740 @default.
- W1972505501 cites W1997596092 @default.
- W1972505501 cites W1999038258 @default.
- W1972505501 cites W2000027727 @default.
- W1972505501 cites W2001931352 @default.
- W1972505501 cites W2005730675 @default.
- W1972505501 cites W2011370181 @default.
- W1972505501 cites W2012613337 @default.
- W1972505501 cites W2014948578 @default.
- W1972505501 cites W2015224461 @default.
- W1972505501 cites W2027006706 @default.
- W1972505501 cites W2027595176 @default.
- W1972505501 cites W2032698400 @default.
- W1972505501 cites W2044466219 @default.
- W1972505501 cites W2045532288 @default.
- W1972505501 cites W2047132238 @default.
- W1972505501 cites W2048904260 @default.
- W1972505501 cites W2050331585 @default.
- W1972505501 cites W2053382418 @default.
- W1972505501 cites W2055924014 @default.
- W1972505501 cites W2056357915 @default.
- W1972505501 cites W2062636920 @default.
- W1972505501 cites W2067923733 @default.
- W1972505501 cites W2068165155 @default.
- W1972505501 cites W2078526156 @default.
- W1972505501 cites W2078786698 @default.
- W1972505501 cites W2082274553 @default.
- W1972505501 cites W2089382742 @default.
- W1972505501 cites W2089399968 @default.
- W1972505501 cites W2089935186 @default.
- W1972505501 cites W2090567774 @default.
- W1972505501 cites W2094233698 @default.
- W1972505501 cites W2098864001 @default.
- W1972505501 cites W2106688439 @default.
- W1972505501 cites W2107970169 @default.
- W1972505501 cites W2116127583 @default.
- W1972505501 cites W2117164638 @default.
- W1972505501 cites W2124209030 @default.
- W1972505501 cites W2131651771 @default.
- W1972505501 cites W2134563387 @default.
- W1972505501 cites W2141304520 @default.
- W1972505501 cites W2143031359 @default.
- W1972505501 cites W2147265361 @default.
- W1972505501 cites W2155444988 @default.
- W1972505501 cites W2162055755 @default.
- W1972505501 cites W4232209704 @default.
- W1972505501 cites W4239494301 @default.
- W1972505501 cites W4243412513 @default.
- W1972505501 cites W4256278325 @default.
- W1972505501 cites W63517249 @default.
- W1972505501 doi "https://doi.org/10.1016/j.expneurol.2004.08.027" @default.
- W1972505501 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15530892" @default.
- W1972505501 hasPublicationYear "2004" @default.
- W1972505501 type Work @default.
- W1972505501 sameAs 1972505501 @default.
- W1972505501 citedByCount "33" @default.
- W1972505501 countsByYear W19725055012012 @default.
- W1972505501 countsByYear W19725055012013 @default.
- W1972505501 countsByYear W19725055012014 @default.
- W1972505501 countsByYear W19725055012016 @default.
- W1972505501 countsByYear W19725055012018 @default.
- W1972505501 countsByYear W19725055012019 @default.
- W1972505501 countsByYear W19725055012020 @default.
- W1972505501 countsByYear W19725055012021 @default.
- W1972505501 crossrefType "journal-article" @default.
- W1972505501 hasAuthorship W1972505501A5020981755 @default.
- W1972505501 hasAuthorship W1972505501A5051342938 @default.
- W1972505501 hasAuthorship W1972505501A5063173227 @default.
- W1972505501 hasAuthorship W1972505501A5071998693 @default.
- W1972505501 hasAuthorship W1972505501A5077560958 @default.
- W1972505501 hasAuthorship W1972505501A5082356752 @default.
- W1972505501 hasAuthorship W1972505501A5086473480 @default.
- W1972505501 hasConcept C126322002 @default.
- W1972505501 hasConcept C134018914 @default.
- W1972505501 hasConcept C15744967 @default.
- W1972505501 hasConcept C169760540 @default.
- W1972505501 hasConcept C169900460 @default.