Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972507165> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1972507165 endingPage "194" @default.
- W1972507165 startingPage "188" @default.
- W1972507165 abstract "Positive end-expiratory pressure (PEEP) improves oxygenation but, at moderate levels, limits portal blood flow (PBF) and may cause relative splanchnic ischemia. Under these conditions, methods of supporting gut physiology may prevent the sequelae of gut ischemic damage. Enteral feeding is known to cause splanchnic hyperemia in uninjured animals. In order to study the effects of continuous enteral feeding on gut hemodynamics in a flow-limited environment, six dogs underwent the insertion of arterial, pulmonary artery, and portal and hepatic vein catheters. Splenectomy and duodenostomy were performed, and the hepatic artery and portal vein were encircled with flow probes. Lung injury (LI) was undertaken with intravenous oleic acid (0.08 mL/kg), followed by incremental additions of PEEP totaling 10 cm H2O to correct shunt. Continuous elemental feeding (1 kcal/mL, 3 mL/kg/hr) was started through the duodenostomy. Cardiac index (CI), PBF, and gut oxygen delivery and consumption (GO2D, GO2C) were measured at baseline (T0), 1 hour after LI and PEEP (T1), and 1 hour after drip feeding was begun (T2). Lung injury and PEEP significantly decreased CI, PBF, and GO2D without changing GO2C. Feeding returned PBF and GO2D to baseline levels without changing CI. GO2C increased significantly compared with baseline levels. Based on prior studies, these changes do not represent recovery of the injured model. Continuous enteral feeding, therefore, redistributed CI to the portal circulation. The improved gut hemodynamics documented in this model may preserve splanchnic integrity and prevent gut-derived complications." @default.
- W1972507165 created "2016-06-24" @default.
- W1972507165 creator A5021868505 @default.
- W1972507165 creator A5038627086 @default.
- W1972507165 creator A5064656041 @default.
- W1972507165 creator A5074764752 @default.
- W1972507165 date "1993-01-01" @default.
- W1972507165 modified "2023-09-25" @default.
- W1972507165 title "Continuous duodenal feeding restores gut blood flow and increases gut oxygen utilization during PEEP ventilation for lung injury" @default.
- W1972507165 cites W1687707398 @default.
- W1972507165 cites W1827131848 @default.
- W1972507165 cites W1984542908 @default.
- W1972507165 cites W2003912121 @default.
- W1972507165 cites W2024333236 @default.
- W1972507165 cites W2027959152 @default.
- W1972507165 cites W2039765689 @default.
- W1972507165 cites W2041537171 @default.
- W1972507165 cites W2043367722 @default.
- W1972507165 cites W2050490554 @default.
- W1972507165 cites W2069487536 @default.
- W1972507165 cites W2072499050 @default.
- W1972507165 cites W2094616149 @default.
- W1972507165 cites W2120874741 @default.
- W1972507165 cites W2123268542 @default.
- W1972507165 cites W2149898470 @default.
- W1972507165 cites W4298977879 @default.
- W1972507165 doi "https://doi.org/10.1016/s0002-9610(05)80424-6" @default.
- W1972507165 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8418696" @default.
- W1972507165 hasPublicationYear "1993" @default.
- W1972507165 type Work @default.
- W1972507165 sameAs 1972507165 @default.
- W1972507165 citedByCount "54" @default.
- W1972507165 countsByYear W19725071652014 @default.
- W1972507165 countsByYear W19725071652015 @default.
- W1972507165 countsByYear W19725071652016 @default.
- W1972507165 countsByYear W19725071652018 @default.
- W1972507165 countsByYear W19725071652019 @default.
- W1972507165 countsByYear W19725071652020 @default.
- W1972507165 countsByYear W19725071652021 @default.
- W1972507165 crossrefType "journal-article" @default.
- W1972507165 hasAuthorship W1972507165A5021868505 @default.
- W1972507165 hasAuthorship W1972507165A5038627086 @default.
- W1972507165 hasAuthorship W1972507165A5064656041 @default.
- W1972507165 hasAuthorship W1972507165A5074764752 @default.
- W1972507165 hasConcept C126322002 @default.
- W1972507165 hasConcept C127413603 @default.
- W1972507165 hasConcept C164705383 @default.
- W1972507165 hasConcept C178853913 @default.
- W1972507165 hasConcept C200457457 @default.
- W1972507165 hasConcept C2775849017 @default.
- W1972507165 hasConcept C2777080012 @default.
- W1972507165 hasConcept C2777714996 @default.
- W1972507165 hasConcept C2781046184 @default.
- W1972507165 hasConcept C42219234 @default.
- W1972507165 hasConcept C44315111 @default.
- W1972507165 hasConcept C70289976 @default.
- W1972507165 hasConcept C71924100 @default.
- W1972507165 hasConcept C78519656 @default.
- W1972507165 hasConcept C78722104 @default.
- W1972507165 hasConceptScore W1972507165C126322002 @default.
- W1972507165 hasConceptScore W1972507165C127413603 @default.
- W1972507165 hasConceptScore W1972507165C164705383 @default.
- W1972507165 hasConceptScore W1972507165C178853913 @default.
- W1972507165 hasConceptScore W1972507165C200457457 @default.
- W1972507165 hasConceptScore W1972507165C2775849017 @default.
- W1972507165 hasConceptScore W1972507165C2777080012 @default.
- W1972507165 hasConceptScore W1972507165C2777714996 @default.
- W1972507165 hasConceptScore W1972507165C2781046184 @default.
- W1972507165 hasConceptScore W1972507165C42219234 @default.
- W1972507165 hasConceptScore W1972507165C44315111 @default.
- W1972507165 hasConceptScore W1972507165C70289976 @default.
- W1972507165 hasConceptScore W1972507165C71924100 @default.
- W1972507165 hasConceptScore W1972507165C78519656 @default.
- W1972507165 hasConceptScore W1972507165C78722104 @default.
- W1972507165 hasIssue "1" @default.
- W1972507165 hasLocation W19725071651 @default.
- W1972507165 hasLocation W19725071652 @default.
- W1972507165 hasOpenAccess W1972507165 @default.
- W1972507165 hasPrimaryLocation W19725071651 @default.
- W1972507165 hasRelatedWork W1977913864 @default.
- W1972507165 hasRelatedWork W2026766109 @default.
- W1972507165 hasRelatedWork W2053635821 @default.
- W1972507165 hasRelatedWork W2220929940 @default.
- W1972507165 hasRelatedWork W2326711960 @default.
- W1972507165 hasRelatedWork W2333090060 @default.
- W1972507165 hasRelatedWork W2403281239 @default.
- W1972507165 hasRelatedWork W2464780846 @default.
- W1972507165 hasRelatedWork W2949785284 @default.
- W1972507165 hasRelatedWork W3085997565 @default.
- W1972507165 hasVolume "165" @default.
- W1972507165 isParatext "false" @default.
- W1972507165 isRetracted "false" @default.
- W1972507165 magId "1972507165" @default.
- W1972507165 workType "article" @default.