FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972508039> ?p ?o ?g. }

• W1972508039 endingPage "237" @default.
• W1972508039 startingPage "227" @default.
• W1972508039 abstract "Nitric oxide (NO) is an intra- and extracellular messenger that mediates diverse signaling pathways in target cells and is known to play an important role in many physiological processes including neuronal signaling, immune response, inflammatory response, modulation of ion channels, phagocytic defense mechanism, penile erection, and cardiovascular homeostasis and its decompensation in atherogenesis. Recent studies have also revealed a role for NO as signaling molecule in plant, as it activates various defense genes and acts as developmental regulator. In plants, NO can also be produced by nitrate reductase. NO can operate through posttranslational modification of proteins (nitrosylation). NO is also a causative agent in various pathophysiological abnormalities. One of the very important systems, the cardiovascular system, is affected by NO production, as this bioactive molecule is involved in the regulation of cardiovascular motor tone, modulation of myocardial contractivity, control of cell proliferation, and inhibition of platelet activation, aggregation, and adhesion. The prime source of NO in the cardiovascular system is endothelial NO synthase, which is tightly regulated with respect to activity and localization. The inhibition of chronic NO synthesis leads to neurogenic and arterial hypertensions, which later contribute to development of myocardial fibrosis. Overall, the modulation of NO synthesis is associated with hypertension. This review briefly describes the physiology of NO, its synthesis, catabolism, and targeting, the mechanism of NO action, and the pharmacological role of NO with special reference to its essential role in hypertension." @default.
• W1972508039 created "2016-06-24" @default.
• W1972508039 creator A5023350983 @default.
• W1972508039 creator A5026558664 @default.
• W1972508039 creator A5054711734 @default.
• W1972508039 creator A5065479414 @default.
• W1972508039 date "2004-01-01" @default.
• W1972508039 modified "2023-10-17" @default.
• W1972508039 title "Nitric Oxide as a Unique Bioactive Signaling Messenger in Physiology and Pathophysiology" @default.
• W1972508039 cites W1269597682 @default.
• W1972508039 cites W1434707050 @default.
• W1972508039 cites W1498251513 @default.
• W1972508039 cites W1522377176 @default.
• W1972508039 cites W1529433619 @default.
• W1972508039 cites W1973457181 @default.
• W1972508039 cites W1984776459 @default.
• W1972508039 cites W1986197498 @default.
• W1972508039 cites W1987165240 @default.
• W1972508039 cites W1990292989 @default.
• W1972508039 cites W1994595673 @default.
• W1972508039 cites W1998998834 @default.
• W1972508039 cites W2002337871 @default.
• W1972508039 cites W2007737411 @default.
• W1972508039 cites W2015230796 @default.
• W1972508039 cites W2018992923 @default.
• W1972508039 cites W2021073062 @default.
• W1972508039 cites W2024380450 @default.
• W1972508039 cites W2024839012 @default.
• W1972508039 cites W2026926934 @default.
• W1972508039 cites W2032010399 @default.
• W1972508039 cites W2032186330 @default.
• W1972508039 cites W2033430036 @default.
• W1972508039 cites W2037159578 @default.
• W1972508039 cites W2038603303 @default.
• W1972508039 cites W2043813681 @default.
• W1972508039 cites W2045079760 @default.
• W1972508039 cites W2045441583 @default.
• W1972508039 cites W2053019030 @default.
• W1972508039 cites W2061878037 @default.
• W1972508039 cites W2068403366 @default.
• W1972508039 cites W2070750080 @default.
• W1972508039 cites W2073132923 @default.
• W1972508039 cites W2073497750 @default.
• W1972508039 cites W2074834026 @default.
• W1972508039 cites W2077439135 @default.
• W1972508039 cites W2079740701 @default.
• W1972508039 cites W2079776507 @default.
• W1972508039 cites W2081519152 @default.
• W1972508039 cites W2084076508 @default.
• W1972508039 cites W2084110843 @default.
• W1972508039 cites W2084248258 @default.
• W1972508039 cites W2085126876 @default.
• W1972508039 cites W2091555940 @default.
• W1972508039 cites W2097791968 @default.
• W1972508039 cites W2100628831 @default.
• W1972508039 cites W2100836459 @default.
• W1972508039 cites W2101882973 @default.
• W1972508039 cites W2103462771 @default.
• W1972508039 cites W2106181213 @default.
• W1972508039 cites W2111730001 @default.
• W1972508039 cites W2115796098 @default.
• W1972508039 cites W2118023300 @default.
• W1972508039 cites W2123333793 @default.
• W1972508039 cites W2124131808 @default.
• W1972508039 cites W2125645851 @default.
• W1972508039 cites W2126009455 @default.
• W1972508039 cites W2126061278 @default.
• W1972508039 cites W2130345110 @default.
• W1972508039 cites W2133680979 @default.
• W1972508039 cites W2137838799 @default.
• W1972508039 cites W2141114070 @default.
• W1972508039 cites W2141719916 @default.
• W1972508039 cites W2145859001 @default.
• W1972508039 cites W2150994390 @default.
• W1972508039 cites W2168065352 @default.
• W1972508039 cites W2170181181 @default.
• W1972508039 cites W2254206576 @default.
• W1972508039 cites W2290538778 @default.
• W1972508039 cites W2341645956 @default.
• W1972508039 cites W2394744099 @default.
• W1972508039 cites W2403278268 @default.
• W1972508039 cites W2409131484 @default.
• W1972508039 cites W2417377668 @default.
• W1972508039 cites W2950369001 @default.
• W1972508039 cites W4231929280 @default.
• W1972508039 cites W2440049585 @default.
• W1972508039 doi "https://doi.org/10.1155/s1110724304402034" @default.
• W1972508039 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/555773" @default.
• W1972508039 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15467163" @default.
• W1972508039 hasPublicationYear "2004" @default.
• W1972508039 type Work @default.
• W1972508039 sameAs 1972508039 @default.
• W1972508039 citedByCount "178" @default.
• W1972508039 countsByYear W19725080392012 @default.
• W1972508039 countsByYear W19725080392013 @default.
• W1972508039 countsByYear W19725080392014 @default.
• W1972508039 countsByYear W19725080392015 @default.
• W1972508039 countsByYear W19725080392016 @default.

• next